8CU7
 
 | | Crystal structure of A2AAR-StaR2-bRIL in complex with a novel A2a antagonist, LJ-4517 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3R,4R)-2-[(8P)-6-amino-2-(hex-1-yn-1-yl)-8-(thiophen-2-yl)-9H-purin-9-yl]oxolane-3,4-diol, Adenosine receptor A2a,Soluble cytochrome b562, ... | | 著者 | Shiriaeva, A, Park, D.-J, Kim, G, Lee, Y, Hou, X, Jarhad, D.B, Kim, G, Yu, J, Hyun, Y.E, Kim, W, Gao, Z.-G, Jacobson, K.A, Han, G.W, Stevens, R.C, Jeong, L.S, Choi, S, Cherezov, V. | | 登録日 | 2022-05-16 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A 2A Adenosine Receptor.
J.Med.Chem., 65, 2022
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8Q3W
 | | ATP-bound IstB in complex to duplex DNA | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (48-MER) Target DNA FW, DNA (48-MER) Traget DNA Rv, ... | | 著者 | de la Gandara, A, Spinola-Amilibia, M, Araujo-Bazan, L, Nunez-Ramirez, R, Berger, J.M, Arias-Palomo, E. | | 登録日 | 2023-08-04 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Molecular basis for transposase activation by a dedicated AAA+ ATPase.
Nature, 630, 2024
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6SXS
 | | GH54 a-l-arabinofuranosidase soaked with cyclic sulfate inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | McGregor, N.G.S, Davies, G.J, Nin-Hill, A, Rovira, C. | | 登録日 | 2019-09-26 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.859 Å) | | 主引用文献 | Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining alpha-l-Arabinofuranosidases.
J.Am.Chem.Soc., 142, 2020
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8U4K
 | | Structure of the HER2/HER4/BTC Heterodimer Extracellular Domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betacellulin, ... | | 著者 | Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. | | 登録日 | 2023-09-10 | | 公開日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | Structure of the HER2/HER4/BTC Heterodimer Extracellular Domain
To Be Published
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6FJO
 | | Adenovirus species 26 knob protein, very high resolution | | 分子名称: | Fiber, GLUTAMIC ACID, GLYCEROL, ... | | 著者 | Rizkallah, P.J, Parker, A.L, Baker, A.T. | | 登録日 | 2018-01-22 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor.
Sci Adv, 5, 2019
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8CZI
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6F8H
 | | antitoxin GraA | | 分子名称: | XRE family transcriptional regulator | | 著者 | Talavera, A, Loris, R. | | 登録日 | 2017-12-13 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.
Nat Commun, 10, 2019
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8A22
 | | Structure of the mitochondrial ribosome from Polytomella magna | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Tobiasson, V, Berzina, I, Amunts, A. | | 登録日 | 2022-06-02 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Structure of a mitochondrial ribosome with fragmented rRNA in complex with membrane-targeting elements.
Nat Commun, 13, 2022
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7ZTB
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7BRU
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7BS6
 | | Bovine Pancreatic Trypsin with 2-Methyltryptamine (Cryo) | | 分子名称: | 2-(2-methyl-1H-indol-3-yl)ethanamine, CALCIUM ION, Cationic trypsin, ... | | 著者 | Maeki, M, Ito, S, Takeda, R, Funakubo, T, Ueno, G, Ishida, A, Tani, H, Yamamoto, M, Tokeshi, M. | | 登録日 | 2020-03-30 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis.
Chem Sci, 11, 2020
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6PLE
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6C0W
 | | Cryo-EM structure of human kinetochore protein CENP-N with the centromeric nucleosome containing CENP-A | | 分子名称: | 147 mer DNA, Centromere protein N, Histone H2A, ... | | 著者 | Zhou, K, Pentakota, S, Vetter, I.R, Morgan, G.P, Petrovic, A, Musacchio, A, Luger, K. | | 登録日 | 2018-01-02 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Decoding the centromeric nucleosome through CENP-N.
Elife, 6, 2017
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8DEL
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7Q9L
 | | Transthyretin complexed with (E)-4-(2-(naphthalen-1-yl)vinyl)benzene-1,2-diol | | 分子名称: | 4-[(~{E})-2-naphthalen-1-ylethenyl]benzene-1,2-diol, GLYCEROL, SODIUM ION, ... | | 著者 | Derbyshire, D.J, Hammarstrom, P, von Castelmur, E, Begum, A. | | 登録日 | 2021-11-12 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Transthyretin Binding Mode Dichotomy of Fluorescent trans -Stilbene Ligands.
Acs Chem Neurosci, 14, 2023
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7TG5
 | | Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK in the Presence of Fe Ion from Yersinia pestis | | 分子名称: | CHLORIDE ION, FE (III) ION, Pirin family protein | | 著者 | Kim, Y, Chhor, G, Endres, M, Babnigg, G, Schneewind, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-01-07 | | 公開日 | 2022-01-19 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK in the presence of Fe ion from Yersinia pestis
To Be Published
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6SF7
 | | Atomic resolution structure of SplF protease from Staphylococcus aureus | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | | 著者 | Golik, P, Stach, N, Karim, A, Dubin, G. | | 登録日 | 2019-08-01 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Determinants of Substrate Specificity of SplF Protease from Staphylococcus aureus .
Int J Mol Sci, 22, 2021
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6VJF
 | | The P-Loop K to A mutation of C. therm Vps1 GTPase-BSE | | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Putative sorting protein Vps1 | | 著者 | Tornabene, B.A, Varlakhanova, N.V, Chappie, J.S, Ford, M.G.J. | | 登録日 | 2020-01-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.472 Å) | | 主引用文献 | Structural and functional characterization of the dominant negative P-loop lysine mutation in the dynamin superfamily protein Vps1.
Protein Sci., 29, 2020
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8D7F
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6PNQ
 | | Crystal structure of the SS2A splice insert-containing neurexin-1 LNS2 domain in complex with neurexophilin-1 | | 分子名称: | Neurexin-1, Neurexophilin-1 | | 著者 | Wilson, S.C, White, K.I, Zhou, Q, Brunger, A.T. | | 登録日 | 2019-07-02 | | 公開日 | 2019-10-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.947 Å) | | 主引用文献 | Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing.
Embo J., 38, 2019
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8FMD
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8DF7
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8U4L
 | | Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... | | 著者 | Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. | | 登録日 | 2023-09-10 | | 公開日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | | 主引用文献 | Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain
To Be Published
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6MHO
 | | Structure of the human TRPV3 channel in the apo conformation | | 分子名称: | Transient receptor potential cation channel subfamily V member 3 | | 著者 | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | | 登録日 | 2018-09-18 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
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5J4C
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S. | | 登録日 | 2016-03-31 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
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