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PDB: 89346 件

8OFP
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Human adenovirus type 24 fiber-knob protein
分子名称: Fiber
著者Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T.
登録日2023-03-16
公開日2023-09-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Broad sialic acid usage amongst species D human adenovirus.
Npj Viruses, 1, 2023
8OFV
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Human adenovirus type 53 fiber-knob protein complexed with sialic acid
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, DI(HYDROXYETHYL)ETHER, ...
著者Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T.
登録日2023-03-16
公開日2023-09-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Broad sialic acid usage amongst species D human adenovirus.
Npj Viruses, 1, 2023
8OME
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Crystal structure of hKHK-A in complex with compound-4
分子名称: Ketohexokinase, compound
著者Ebenhoch, R, Pautsch, A.
登録日2023-03-31
公開日2023-09-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design.
Acta Crystallogr D Struct Biol, 79, 2023
6TCH
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Binary complex of 14-3-3 sigma and a high-affinity non-canonical 9-mer peptide binder
分子名称: 14-3-3 protein sigma, CHLORIDE ION, DLY-NVA-PPN-KCJ-SEP-PPN-B3S-BAL-PPN-LYS, ...
著者Somsen, B.A, Ottmann, C.
登録日2019-11-06
公開日2020-07-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Ultra-large chemical libraries for the discovery of high-affinity peptide binders.
Nat Commun, 11, 2020
8P5Z
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Artificial transfer hydrogenase with a Mn-5 cofactor and Streptavidin S112Y-K121M mutant
分子名称: 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[2-[(5-methylpyridin-2-yl)methylamino]ethyl]pentanamide, BROMIDE ION, GLYCEROL, ...
著者Lau, K, Wang, W, Pojer, F, Larabi, A.
登録日2023-05-24
公開日2023-09-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Manganese Transfer Hydrogenases Based on the Biotin-Streptavidin Technology.
Angew.Chem.Int.Ed.Engl., 62, 2023
5K9Q
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Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.a.26 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin
分子名称: 16.a.26 Heavy chain, 16.a.26 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D.
登録日2016-06-01
公開日2016-11-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell(Cambridge,Mass.), 166, 2016
4S2E
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Phosphate ion bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5
分子名称: PHOSPHATE ION, Thymidylate kinase
著者Biswas, A, Jeyakanthan, J, Sekar, K.
登録日2015-01-20
公開日2016-01-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate.
Febs J., 284, 2017
8P5Y
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Artificial transfer hydrogenase with a Mn-12 cofactor and Streptavidin S112Y-K121M mutant
分子名称: 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[2-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)ethyl]pentanamide, BROMIDE ION, CHLORIDE ION, ...
著者Lau, K, Wang, W, Pojer, F, Larabi, A.
登録日2023-05-24
公開日2023-09-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Manganese Transfer Hydrogenases Based on the Biotin-Streptavidin Technology.
Angew.Chem.Int.Ed.Engl., 62, 2023
8OMD
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Crystal structure of mKHK in complex with compound-4
分子名称: Ketohexokinase, compound
著者Ebenhoch, R, Pautsch, A.
登録日2023-03-31
公開日2023-09-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design.
Acta Crystallogr D Struct Biol, 79, 2023
4S3N
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Crystal structure of human OAS3 domain I in complex with dsRNA
分子名称: 2'-5'-oligoadenylate synthase 3, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3')
著者Donovan, J, Whitney, G, Rath, S, Korennykh, A.
登録日2015-02-26
公開日2015-03-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3.
Proc.Natl.Acad.Sci.USA, 112, 2015
6N2X
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Anti-HIV-1 Fab 2G12 + Man9 re-refinement
分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-11-14
公開日2018-11-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science, 300, 2003
8OK6
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Variant Surface Glycoprotein VSG11 two monomers
分子名称: SULFATE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ...
著者Gkeka, A, Vlachou, E.P, Zeelen, J.P, Stebbins, C.E.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8OMF
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Crystal structure of hKHK-C in complex with compound-4
分子名称: Ketohexokinase, SULFATE ION, compound
著者Ebenhoch, R, Pautsch, A.
登録日2023-03-31
公開日2023-09-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design.
Acta Crystallogr D Struct Biol, 79, 2023
3LZP
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BU of 3lzp by Molmil
Crystal Structure Analysis of the 'as-isolated' P19 protein from Campylobacter jejuni at 1.65 A at pH 9.0
分子名称: COPPER (II) ION, P19 protein, SULFATE ION
著者Doukov, T.I, Chan, A.C.K, Scofield, M, Ramin, A.B, Tom-Yew, S.A.L, Murphy, M.E.P.
登録日2010-03-01
公開日2010-07-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni.
J.Mol.Biol., 401, 2010
4TRM
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BU of 4trm by Molmil
Structure of the apo form of InhA from Mycobacterium tuberculosis
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Enoyl-[acyl-carrier-protein] reductase [NADH]
著者Chollet, A, Julien, S, Mourey, L, Maveyraud, L.
登録日2014-06-17
公開日2015-04-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach.
J.Struct.Biol., 190, 2015
7MWQ
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BU of 7mwq by Molmil
Structure of De Novo designed beta sheet heterodimer LHD29A53/B53
分子名称: LHD29A53, LHD29B53
著者Bera, A.K, Sahtoe, D.D, Kang, A, Praetorius, F, Baker, D.
登録日2021-05-17
公開日2022-01-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Reconfigurable asymmetric protein assemblies through implicit negative design.
Science, 375, 2022
6PTT
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BU of 6ptt by Molmil
Soluble model of Arabidopsis thaliana CuA (Tt3LAt)
分子名称: Cytochrome c oxidase subunit 2, DINUCLEAR COPPER ION
著者Lisa, M.N, Giannini, E, Llases, M.E, Alzari, P.M, Vila, A.J.
登録日2019-07-16
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Unexpected electron spin density on the axial methionine ligand in CuAsuggests its involvement in electron pathways.
Chem.Commun.(Camb.), 56, 2020
5N4Z
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Crystal structure of human Pim-1 kinase in complex with a consensus peptide and fragment like molecule (E)-4-(4-hydroxyphenyl)but-3-en-2-one
分子名称: (~{E})-4-(4-hydroxyphenyl)but-3-en-2-one, Pimtide, Serine/threonine-protein kinase pim-1
著者Siefker, C, Heine, A, Klebe, G.
登録日2017-02-11
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.257 Å)
主引用文献A crystallographic fragment study with human Pim-1 kinase
to be published
8SF6
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Promiscuous amino acid gamma synthase from Caldicellulosiruptor hydrothermalis in closed conformation
分子名称: 2-(2-ETHOXYETHOXY)ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
著者Buller, A.R, Zmich, A.P, Bingman, C.A.
登録日2023-04-10
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Multiplexed Assessment of Promiscuous Non-Canonical Amino Acid Synthase Activity in a Pyridoxal Phosphate-Dependent Protein Family.
Acs Catalysis, 13, 2023
5FYX
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Crystal structure of Drosophila NCS-1 bound to penothiazine FD16
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, FREQUENIN 2, ...
著者Martinez-Gonzalez, L, Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J.
登録日2016-03-10
公開日2017-01-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8R79
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The D2 domain of human DTX3L
分子名称: E3 ubiquitin-protein ligase DTX3L, SULFATE ION
著者Vela-Rodriguez, C, Lehtio, L, Maksimainen, M, Duman, R, Wagner, A, Glumoff, T.
登録日2023-11-24
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Oligomerisation mediated by the D2 domain of DTX3L is critical for DTX3L-PARP9 reading function of mono-ADP-ribosylated androgen receptor.
Biorxiv, 2023
4TTJ
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BU of 4ttj by Molmil
Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 6 FMC molecules
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ...
著者Stefanic, Z, Bzowska, A.
登録日2014-06-21
公開日2015-07-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.874 Å)
主引用文献Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis.
Sci Rep, 8, 2018
8P1H
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Crystal structure of the chimera of human 14-3-3 zeta and phosphorylated cytoplasmic loop fragment of the alpha7 acetylcholine receptor
分子名称: 1,2-ETHANEDIOL, AZIDE ION, BENZOIC ACID, ...
著者Boyko, K.M, Kapitonova, A.A, Tugaeva, K.V, Varfolomeeva, L.A, Lyukmanova, E.N, Sluchanko, N.N.
登録日2023-05-12
公開日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure reveals canonical recognition of the phosphorylated cytoplasmic loop of human alpha7 nicotinic acetylcholine receptor by 14-3-3 protein.
Biochem.Biophys.Res.Commun., 682, 2023
8CCN
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BU of 8ccn by Molmil
Filamentous actin II from Plasmodium falciparum
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-2, MAGNESIUM ION
著者Kursula, I, Lopez, A.J.
登録日2023-01-27
公開日2023-02-22
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and function of Plasmodium actin II in the parasite mosquito stages.
Plos Pathog., 19, 2023
7MWR
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BU of 7mwr by Molmil
Structure of De Novo designed beta sheet heterodimer LHD101A53/B4
分子名称: LHD101A54, LHD101B4, MALONATE ION
著者Bera, A.K, Sahtoe, D.D, Kang, A, Praetorius, F, Baker, D.
登録日2021-05-17
公開日2022-01-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Reconfigurable asymmetric protein assemblies through implicit negative design.
Science, 375, 2022

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