4S2E

Phosphate ion bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

Summary for 4S2E

Related2PBR
DescriptorThymidylate kinase, PHOSPHATE ION (3 entities in total)
Functional Keywordstransferase, atp binding, tmp binding
Biological sourceAquifex aeolicus
Total number of polymer chains2
Total molecular weight44995.86
Authors
Biswas, A.,Jeyakanthan, J.,Sekar, K. (deposition date: 2015-01-20, release date: 2016-01-20, Last modification date: 2017-06-28)
Primary citation
Biswas, A.,Jeyakanthan, J.,Sekar, K.
Structural studies of a hyperthermophilic Thymidylate Kinase enzyme reveal conformational sub-states along the reaction coordinate
Febs J., 2017
Experimental method
X-RAY DIFFRACTION (2.35 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.267201.0%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution