5N4Z

Crystal structure of human Pim-1 kinase in complex with a consensus peptide and fragment like molecule (E)-4-(4-hydroxyphenyl)but-3-en-2-one

Summary for 5N4Z

• Entry DOI: 10.2210/pdb5n4z/pdb
• Descriptor: Serine/threonine-protein kinase pim-1, Pimtide, (~{E})-4-(4-hydroxyphenyl)but-3-en-2-one, ... (4 entities in total)
• Functional Keywords: serine threonine kinase, transferase, proto-oncogene, fragment, pim-1, consensus peptide
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 37387.64

Authors

Siefker, C.,Heine, A.,Klebe, G. (deposition date: 2017-02-11, release date: 2018-02-28, Last modification date: 2024-01-17)

• Primary citation: Siefker, C.,Heine, A.,Hardes, K.,Steinmetzer, A.,Klebe, G.; A crystallographic fragment study with human Pim-1 kinase; to be published,

Experimental method

X-RAY DIFFRACTION (2.257 Å)