Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 89346 件

6WCO
DownloadVisualize
BU of 6wco by Molmil
Structure of SARS main protease bound to inhibitor X47
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Main protease, ...
著者Mesecar, A.D, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-03-30
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献A taxonomically-driven approach to development of potent, broad-spectrum inhibitors of coronavirus main protease including SARS-CoV-2 (COVID-19)
To Be Published
7QRW
DownloadVisualize
BU of 7qrw by Molmil
Crystal structure of NHL domain of TRIM3
分子名称: GLYCEROL, Isoform 4 of Tripartite motif-containing protein 3, SULFATE ION
著者Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC)
登録日2022-01-12
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Comparative structural analyses of the NHL domains from the human E3 ligase TRIM-NHL family.
Iucrj, 9, 2022
6SPG
DownloadVisualize
BU of 6spg by Molmil
Pseudomonas aeruginosa 70s ribosome from a clinical isolate
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Halfon, Y, Jimenez-Fernande, A, La Ros, R, Espinos, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S, Yonath, A.
登録日2019-09-01
公開日2019-10-16
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
6X0K
DownloadVisualize
BU of 6x0k by Molmil
Structure of dithionite-reduced SidA ornithine hydroxylase with the FAD "in" and complexed with L-ornithine
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-ornithine, L-ornithine N(5)-monooxygenase
著者Tanner, J.J, Campbell, A.C.
登録日2020-05-15
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.231 Å)
主引用文献Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6XKL
DownloadVisualize
BU of 6xkl by Molmil
SARS-CoV-2 HexaPro S One RBD up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Wrapp, D, Hsieh, C.-L, Goldsmith, J.A, McLellan, J.S.
登録日2020-06-26
公開日2020-07-15
最終更新日2020-09-30
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.
Science, 369, 2020
6XM5
DownloadVisualize
BU of 6xm5 by Molmil
Structure of SARS-CoV-2 spike at pH 5.5, all RBDs down
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhou, T, Tsybovsky, Y, Olia, A, Kwong, P.D.
登録日2020-06-29
公開日2020-07-29
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
8FYV
DownloadVisualize
BU of 8fyv by Molmil
Salmonella enterica serovar Typhimurium chemoreceptor Tsr (taxis to serine and repellents) ligand-binding domain in complex with l-serine
分子名称: CHLORIDE ION, Methyl-accepting chemotaxis protein, SERINE, ...
著者Baylink, A, Gentry-Lear, Z, Glenn, S.
登録日2023-01-26
公開日2024-05-15
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Bacterial vampirism mediated through taxis to serum.
Elife, 12, 2024
7O81
DownloadVisualize
BU of 7o81 by Molmil
Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
著者Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N.
登録日2021-04-14
公開日2021-06-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
6WKP
DownloadVisualize
BU of 6wkp by Molmil
Crystal structure of RNA-binding domain of nucleocapsid phosphoprotein from SARS CoV-2, monoclinic crystal form
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoprotein, ZINC ION
著者Chang, C, Michalska, K, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Kim, Y, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-04-16
公開日2020-04-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
6X5H
DownloadVisualize
BU of 6x5h by Molmil
Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP
分子名称: 1,2-ETHANEDIOL, Alpha-(1,6)-fucosyltransferase, GLYCEROL, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-05-26
公開日2020-10-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.
J.Biol.Chem., 295, 2020
8C6C
DownloadVisualize
BU of 8c6c by Molmil
Light SFX structure of D.m(6-4)photolyase at 300ps time delay
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2023-01-11
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
8C6H
DownloadVisualize
BU of 8c6h by Molmil
Light SFX structure of D.m(6-4)photolyase at 2ps time delay
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2023-01-11
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
6QDH
DownloadVisualize
BU of 6qdh by Molmil
Leishmania major N-myristoyltransferase in complex with quinazoline inhibitor IMP-0000906
分子名称: 4-[ethyl(methyl)amino]-2-[methyl-(1-methylpiperidin-4-yl)amino]-~{N}-(1,3,5-trimethylpyrazol-4-yl)quinazoline-6-sulfonamide, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ...
著者Brannigan, J.A.
登録日2019-01-01
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes.
J.Med.Chem., 63, 2020
5NNP
DownloadVisualize
BU of 5nnp by Molmil
Structure of Naa15/Naa10 bound to HypK-THB
分子名称: CARBOXYMETHYL COENZYME *A, GLYCEROL, N-terminal acetyltransferase-like protein, ...
著者Weyer, F.A, Gumiero, A, Kopp, J, Sinning, I.
登録日2017-04-10
公開日2017-06-14
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献Structural basis of HypK regulating N-terminal acetylation by the NatA complex.
Nat Commun, 8, 2017
8FK0
DownloadVisualize
BU of 8fk0 by Molmil
Asymmetric cryo-EM structure of a curved Saccharolobus solfataricus type IV pilus
分子名称: Pilin_N domain-containing protein
著者Kreutzberger, M.A, Wang, F, Krupovic, M, Egelman, E.H.
登録日2022-12-20
公開日2023-06-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献The evolution of archaeal flagellar filaments.
Proc.Natl.Acad.Sci.USA, 120, 2023
8C1U
DownloadVisualize
BU of 8c1u by Molmil
SFX structure of D.m(6-4)photolyase
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2022-12-21
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
7O7Y
DownloadVisualize
BU of 7o7y by Molmil
Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution)
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
著者Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N.
登録日2021-04-14
公開日2021-06-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
8C69
DownloadVisualize
BU of 8c69 by Molmil
Light SFX structure of D.m(6-4)photolyase at 100 microsecond time delay
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2023-01-11
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
6XHX
DownloadVisualize
BU of 6xhx by Molmil
Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with erythromycin and protein Y (YfiA) at 2.55A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S.
登録日2020-06-19
公開日2020-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Nat.Chem.Biol., 17, 2021
8C6A
DownloadVisualize
BU of 8c6a by Molmil
Light SFX structure of D.m(6-4)photolyase at 1ps time delay
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2023-01-11
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
8C6B
DownloadVisualize
BU of 8c6b by Molmil
Light SFX structure of D.m(6-4)photolyase at 20ps time delay
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2023-01-11
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
6WN9
DownloadVisualize
BU of 6wn9 by Molmil
Structure of Staphylococcus aureus peptidoglycan O-acetyltransferase A (OatA) C-terminal catalytic domain, Zn-bound
分子名称: Acetyltransferase, ZINC ION
著者Jones, C.J, Sychantha, D, Howell, P.L, Clarke, A.J.
登録日2020-04-22
公開日2020-05-06
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for theO-acetyltransferase function of the extracytoplasmic domain of OatA fromStaphylococcus aureus.
J.Biol.Chem., 295, 2020
6XCF
DownloadVisualize
BU of 6xcf by Molmil
Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with noncovalent inhibitor 59
分子名称: (3R)-3-(2,4-dichlorophenyl)-N~1~-hydroxy-N~5~-pentylpentanediamide, Botulinum neurotoxin type A, ZINC ION
著者Tararina, M.A, Allen, K.N.
登録日2020-06-08
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A.
J.Med.Chem., 63, 2020
8C6F
DownloadVisualize
BU of 8c6f by Molmil
Light SFX structure of D.m(6-4)photolyase at 400fs time delay
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S.
登録日2023-01-11
公開日2023-11-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography.
Nat.Chem., 16, 2024
5NPP
DownloadVisualize
BU of 5npp by Molmil
2.22A STRUCTURE OF THIOPHENE2 AND GSK945237 WITH S.AUREUS DNA GYRASE AND DNA
分子名称: (1R)-1-[(4-{[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl]amino}piperidin-1-yl)methyl]-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one, DIMETHYL SULFOXIDE, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ...
著者Bax, B.D, Chan, P.F, Stavenger, R.A.
登録日2017-04-18
公開日2017-07-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

225946

件を2024-10-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon