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PDB: 89774 件

8QRD
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OleP in complex with testosterone in high salt crystallization conditions
分子名称: Cytochrome P-450, FORMIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Fata, F, Costanzo, A, Freda, I, Gugole, E, Bulfaro, G, Barbizzi, L, Di Renzo, M, Savino, C, Vallone, B, Montemiglio, L.C.
登録日2023-10-06
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献OleP in complex with testosterone in high salt crystallization conditions
To Be Published
6EWS
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BU of 6ews by Molmil
Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12A-NDD
分子名称: NRPS Kj12A-NDD
著者Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J.
登録日2017-11-06
公開日2018-10-31
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS.
Nat Commun, 9, 2018
3AV3
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BU of 3av3 by Molmil
Crystal structure of glycinamide ribonucleotide transformylase 1 from Geobacillus kaustophilus
分子名称: MAGNESIUM ION, Phosphoribosylglycinamide formyltransferase
著者Kanagawa, M, Baba, S, Nakagawa, N, Ebihara, A, Kuramitsu, S, Yokoyama, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-02-18
公開日2012-03-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures and reaction mechanisms of the two related enzymes, PurN and PurU.
J.Biochem., 154, 2013
1TX7
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BU of 1tx7 by Molmil
Bovine Trypsin complexed with p-amidinophenylmethylphosphinic acid (AMPA)
分子名称: (4-CARBAMIMIDOYLPHENYL)-METHYL-PHOSPHINIC ACID, CALCIUM ION, Trypsinogen
著者Cui, J, Marankan, F, Fu, W, Crich, D, Mesecar, A, Johnson, M.E.
登録日2004-07-02
公開日2005-09-20
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献An oxyanion-hole selective serine protease inhibitor in complex with trypsin.
Bioorg.Med.Chem., 10, 2002
8QYI
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BU of 8qyi by Molmil
OleP in complex with lithocholic acid in high salt crystallization conditions
分子名称: (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, Cytochrome P-450, FORMIC ACID, ...
著者Fata, F, Costanzo, A, Freda, I, Gugole, E, Bulfaro, G, Barbizzi, L, Di Renzo, M, Savino, C, Vallone, B, Montemiglio, L.C.
登録日2023-10-26
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献OleP in complex with lithocolic acid in high salt crystallization conditions
To Be Published
1KU9
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BU of 1ku9 by Molmil
X-ray Structure of a Methanococcus jannaschii DNA-Binding Protein: Implications for Antibiotic Resistance in Staphylococcus aureus
分子名称: hypothetical protein MJ223
著者Ray, S.S, Bonanno, J.B, Chen, H, de Lencastre, H, Wu, S, Tomasz, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2002-01-21
公開日2002-12-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-ray structure of an M. jannaschii DNA-binding protein: implications for antibiotic resistance in S. aureus
Proteins, 50, 2002
8Q69
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BU of 8q69 by Molmil
Crystal structure of HsRNMT complexed with inhibitor DDD1060606
分子名称: 1-[(3~{S})-3-(2~{H}-pyrazolo[3,4-b]pyridin-3-yl)piperidin-1-yl]-2-thiophen-3-yl-ethanone, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Petit, A.P, Fyfe, P.K.
登録日2023-08-11
公開日2024-08-21
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structure-Guided Design of HsRNMT inhibitors
To Be Published
8Q8G
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BU of 8q8g by Molmil
Crystal structure of HsRNMT complexed with inhibitor DDD1870799
分子名称: 2-(4-fluorophenyl)-1-[(3~{S})-3-(6-oxidanyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)piperidin-1-yl]ethanone, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Petit, A.P, Fyfe, P.K.
登録日2023-08-18
公開日2024-08-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-Guided Design of HsRNMT inhibitors
To Be Published
3OCQ
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BU of 3ocq by Molmil
crystal structure of tRNA-specific Adenosine deaminase from Salmonella enterica
分子名称: Putative Cytosine/adenosine deaminase, ZINC ION
著者Kim, J, Ramagopal, U.A, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-08-10
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of tRNA-specific Adenosine deaminase from Salmonella enterica
To be Published
8Q9W
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BU of 8q9w by Molmil
Crystal structure of HsRNMT complexed with sinefungin and GMP-PnP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SINEFUNGIN, SULFATE ION, ...
著者Petit, A.P, Fyfe, P.K.
登録日2023-08-21
公開日2024-09-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Guided Design of HsRNMT inhibitors
To Be Published
8QF6
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BU of 8qf6 by Molmil
Sulfoxide synthase from Chloracidobacterium thermophilum, EgtB type II, in complex with iron and trimethylhistidine
分子名称: (2~{S})-2-(dimethylamino)-3-(3-methylimidazol-4-yl)propanoic acid, Ergothioneine biosynthesis protein EgtB, FE (III) ION
著者Vasseur, C.M, Stampfli, A.R, Seebeck, F.P.
登録日2023-09-03
公開日2024-09-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Catalytic mechanism analysis of sulfoxide synthase via inhibition assay
To Be Published
1K59
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BU of 1k59 by Molmil
Crystal Structure of Human Angiogenin Variant Q117G
分子名称: CITRIC ACID, angiogenin
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
5J54
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BU of 5j54 by Molmil
The Structure and Mechanism of NOV1, a Resveratrol-Cleaving Dioxygenase
分子名称: Carotenoid oxygenase, FE (III) ION, OXYGEN MOLECULE, ...
著者McAndrew, R.P, Pereira, J.H, Sathitsuksanoh, N, Sale, K.L, Simmons, B.A, Adams, P.D.
登録日2016-04-01
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
6YXQ
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BU of 6yxq by Molmil
Crystal structure of a DNA repair complex ASCC3-ASCC2
分子名称: Activating signal cointegrator 1 complex subunit 2, Activating signal cointegrator 1 complex subunit 3
著者Jia, J, Absmeier, E, Holton, N, Bohnsack, K.E, Pietrzyk-Brzezinska, A.J, Bohnsack, M.T, Wahl, M.C.
登録日2020-05-03
公開日2020-09-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations.
Nat Commun, 11, 2020
4V9Q
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BU of 4v9q by Molmil
Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Svidritskiy, E, Ling, C, Ermolenko, D.N, Korostelev, A.A.
登録日2013-06-12
公開日2014-07-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 110, 2013
4W7L
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BU of 4w7l by Molmil
CRYSTAL STRUCTURE OF A DECOLORIZING PEROXIDASE (DYP) FROM AURICULARIA AURICULA-JUDAE. D168N MUTANT
分子名称: Dye-decolorizing peroxidase, PROTOPORPHYRIN IX CONTAINING FE
著者Medrano, F.J, Romero, A.
登録日2014-08-22
公開日2015-03-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Catalytic surface radical in dye-decolorizing peroxidase: a computational, spectroscopic and site-directed mutagenesis study.
Biochem.J., 466, 2015
2OLU
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BU of 2olu by Molmil
Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme
分子名称: 1,2-ETHANEDIOL, Penicillin-binding protein 2
著者Lovering, A.L, De Castro, L.H, Lim, D, Strynadka, N.C.
登録日2007-01-19
公開日2007-03-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis.
Science, 315, 2007
1K8K
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BU of 1k8k by Molmil
Crystal Structure of Arp2/3 Complex
分子名称: ACTIN-LIKE PROTEIN 2, ACTIN-LIKE PROTEIN 3, ARP2/3 COMPLEX 16 KDA SUBUNIT, ...
著者Robinson, R.C, Turbedsky, K, Kaiser, D.A, Higgs, H.N, Marchand, J.-B, Choe, S, Pollard, T.D.
登録日2001-10-24
公開日2001-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Arp2/3 Complex
Science, 294, 2001
4V25
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BU of 4v25 by Molmil
VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context- dependent cytostasis in cancer cells
分子名称: MAGNESIUM ION, N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE, N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-N-(4-{[(difluoroacetyl)amino]methyl}benzyl)-2,4-dihydroxybenzamide, ...
著者Moore, J.D, Staniszewska, A, Shaw, T, D'Alessandro, J, Davis, B, Surgenor, A, Baker, L, Matassova, N, Murray, J, Macias, A, Brough, P, Wood, M, Mahon, P.C.
登録日2014-10-06
公開日2014-12-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells.
Oncotarget, 5, 2014
4V4Q
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BU of 4v4q by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D.
登録日2005-08-30
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structures of the bacterial ribosome at 3.5 A resolution.
Science, 310, 2005
4W2I
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BU of 4w2i by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Szal, T, Jiang, F, Gupta, P, Matsuda, R, Shiozuka, M, Steitz, T.A, Vazquez-Laslop, N, Mankin, A.S.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA.
Mol.Cell, 56, 2014
4UT3
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BU of 4ut3 by Molmil
X-ray structure of the human PP1 gamma catalytic subunit treated with hydrogen peroxide
分子名称: MANGANESE (II) ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT
著者Zeh Silva, M, Kopec, J, Fotinou, D, Steiner, R.A.
登録日2014-07-17
公開日2015-07-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Targeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling.
Embo J., 35, 2016
1K5B
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BU of 1k5b by Molmil
Crystal Structure of Human Angiogenin Variant des(121-123)
分子名称: Angiogenin, CITRIC ACID
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
4UT2
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BU of 4ut2 by Molmil
X-ray structure of the human PP1 gamma catalytic subunit treated with ascorbate
分子名称: MANGANESE (II) ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT
著者Kopec, J, Zeh Silva, M, Fotinou, C, Steiner, R.A.
登録日2014-07-17
公開日2015-07-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Targeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling.
Embo J., 35, 2016
2OPT
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BU of 2opt by Molmil
Crystal Structure of Apo ActR from Streptomyces coelicolor.
分子名称: ActII protein
著者Willems, A.R, Junop, M.S.
登録日2007-01-30
公開日2008-02-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA.
J.Mol.Biol., 376, 2008

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