7OKC
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![BU of 7okc by Molmil](/molmil-images/mine/7okc) | Crystal structure of Escherichia coli LpxA in complex with compound 1 | 分子名称: | 2-[2-(2-chlorophenyl)sulfanylethanoyl-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]amino]-N-methyl-ethanamide, Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, SODIUM ION | 著者 | Ryan, M.D, Parkes, A.L, Southey, M, Andersen, O.A, Zahn, M, Barker, J, DeJonge, B.L.M. | 登録日 | 2021-05-17 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa . J.Med.Chem., 64, 2021
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7OO5
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6O41
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6O4Z
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![BU of 6o4z by Molmil](/molmil-images/mine/6o4z) | Structure of HLA-A2:01 with peptide MM92 | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | 著者 | Ying, G, Bitra, A, Zajonc, D.M. | 登録日 | 2019-03-01 | 公開日 | 2020-01-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients. Front Immunol, 10, 2019
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6O51
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![BU of 6o51 by Molmil](/molmil-images/mine/6o51) | Structure of HLA-A2:01 with peptide MM90 | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | 著者 | Ying, G, Bitra, A, Zajonc, D.M. | 登録日 | 2019-03-01 | 公開日 | 2020-01-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients. Front Immunol, 10, 2019
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6QDH
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6YAC
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![BU of 6yac by Molmil](/molmil-images/mine/6yac) | Plant PSI-ferredoxin supercomplex | 分子名称: | (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | 著者 | Caspy, I, Nelson, N, Shkolnisky, Y, Klaiman, D, Sheinker, A. | 登録日 | 2020-03-12 | 公開日 | 2020-09-30 | 最終更新日 | 2020-10-21 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | The structure of a triple complex of plant photosystem I with ferredoxin and plastocyanin. Nat.Plants, 6, 2020
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6OP6
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![BU of 6op6 by Molmil](/molmil-images/mine/6op6) | Structure of VIM-20 in the reduced state | 分子名称: | Metallo-beta-lactamase VIM-20, SODIUM ION, ZINC ION | 著者 | Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C. | 登録日 | 2019-04-24 | 公開日 | 2019-10-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions. Mbio, 10, 2019
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5NO4
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![BU of 5no4 by Molmil](/molmil-images/mine/5no4) | RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate with uS3) | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R. | 登録日 | 2017-04-10 | 公開日 | 2017-05-31 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (5.16 Å) | 主引用文献 | RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket. Nucleic Acids Res., 45, 2017
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5NO2
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![BU of 5no2 by Molmil](/molmil-images/mine/5no2) | RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate) | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R. | 登録日 | 2017-04-10 | 公開日 | 2017-05-24 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (5.16 Å) | 主引用文献 | RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket. Nucleic Acids Res., 45, 2017
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5ME1
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![BU of 5me1 by Molmil](/molmil-images/mine/5me1) | Structure of the 30S Pre-Initiation Complex 2 (30S IC-2) Stalled by GE81112 | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S. | 登録日 | 2016-11-14 | 公開日 | 2017-01-11 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (13.5 Å) | 主引用文献 | Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways. Nucleic Acids Res., 45, 2017
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5MLC
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![BU of 5mlc by Molmil](/molmil-images/mine/5mlc) | Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions | 分子名称: | 23S ribosomal RNA, chloroplastic, 4.8S ribosomal RNA, ... | 著者 | Graf, M, Arenz, S, Huter, P, Doenhoefer, A, Novacek, J, Wilson, D.N. | 登録日 | 2016-12-06 | 公開日 | 2016-12-28 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions. Nucleic Acids Res., 45, 2017
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6WLL
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![BU of 6wll by Molmil](/molmil-images/mine/6wll) | Apo F. nucleatum glycine riboswitch models, 10.0 Angstrom resolution | 分子名称: | RNA (171-MER) | 著者 | Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R. | 登録日 | 2020-04-20 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. Nat.Methods, 17, 2020
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6WLJ
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![BU of 6wlj by Molmil](/molmil-images/mine/6wlj) | ATP-TTR-3 with AMP models, 9.6 Angstrom resolution | 分子名称: | RNA (130-MER) | 著者 | Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R. | 登録日 | 2020-04-20 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (9.6 Å) | 主引用文献 | Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. Nat.Methods, 17, 2020
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6WLT
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![BU of 6wlt by Molmil](/molmil-images/mine/6wlt) | Apo V. cholerae glycine riboswitch models, 4.8 Angstrom resolution | 分子名称: | RNA (231-MER) | 著者 | Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R. | 登録日 | 2020-04-20 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. Nat.Methods, 17, 2020
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8WN8
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![BU of 8wn8 by Molmil](/molmil-images/mine/8wn8) | CryoEM structure of ZIKV rsNS1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1 | 著者 | Chew, B.L.A, Luo, D. | 登録日 | 2023-10-05 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024
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8TKO
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![BU of 8tko by Molmil](/molmil-images/mine/8tko) | KS-AT core of 6-deoxyerythronolide B synthase (DEBS) Module 3 crosslinked with its translocation ACP partner of Module 2 | 分子名称: | EryAI, EryAII | 著者 | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | 登録日 | 2023-07-25 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis To Be Published
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6O9W
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9FFF
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9FFB
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![BU of 9ffb by Molmil](/molmil-images/mine/9ffb) | ss-dsDNA-FANCD2-FANCI complex | 分子名称: | DNA (5'-D(P*CP*GP*AP*TP*GP*TP*CP*TP*CP*TP*AP*GP*AP*CP*AP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*GP*CP*TP*GP*TP*CP*TP*AP*GP*AP*GP*AP*CP*AP*TP*CP*GP*AP*T)-3'), Fanconi anemia complementation group I, ... | 著者 | Alcon, P, Passmore, L.A. | 登録日 | 2024-05-22 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | ss-dsDNA-FANCD2-FANCI complex To Be Published
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9PTI
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8EA4
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![BU of 8ea4 by Molmil](/molmil-images/mine/8ea4) | V-K CAST Transpososome from Scytonema hofmanni, minor configuration | 分子名称: | 30S ribosomal protein S15, ADENOSINE-5'-TRIPHOSPHATE, Cas12k, ... | 著者 | Rizo, A.R, Park, J.-U, Tsai, A.W, Kellogg, E.K. | 登録日 | 2022-08-27 | 公開日 | 2022-11-30 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of the holo CRISPR RNA-guided transposon integration complex. Nature, 613, 2023
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8DMO
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![BU of 8dmo by Molmil](/molmil-images/mine/8dmo) | Structure of open, inward-facing MsbA from E. coli | 分子名称: | ATP-binding transport protein MsbA | 著者 | Liu, C, Lyu, J, Laganowsky, A.D, Zhao, M. | 登録日 | 2022-07-08 | 公開日 | 2022-12-14 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis for lipid and copper regulation of the ABC transporter MsbA. Nat Commun, 13, 2022
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6OBA
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![BU of 6oba by Molmil](/molmil-images/mine/6oba) | The beta2 adrenergic receptor bound to a negative allosteric modulator | 分子名称: | (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, 6-bromo-N~2~-phenylquinazoline-2,4-diamine, Beta-2 adrenergic receptor,Lysozyme,Beta-2 adrenergic receptor, ... | 著者 | Liu, X, Stobel, A, Kaindl, J, Dengler, D, ClarK, M, Mahoney, J, Korczynska, M, Matt, R.A, Hubner, H, Xu, X, Stanek, M, Hirata, K, Shoichet, B, Sunahara, R, Gmeiner, R, Kobilka, B.K. | 登録日 | 2019-03-20 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | An allosteric modulator binds to a conformational hub in the beta2adrenergic receptor. Nat.Chem.Biol., 16, 2020
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7P3J
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![BU of 7p3j by Molmil](/molmil-images/mine/7p3j) | EED in complex with compound 4 | 分子名称: | 8-[6-[(dimethylamino)methyl]-2-methyl-pyridin-3-yl]-5-[(5-fluoranyl-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2H-pyrido[3,4-d]pyridazin-1-one, MAGNESIUM ION, N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... | 著者 | Read, J.A. | 登録日 | 2021-07-07 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase. J.Med.Chem., 64, 2021
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