3ZM2
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![BU of 3zm2 by Molmil](/molmil-images/mine/3zm2) | Catalytic domain of human SHP2 | 分子名称: | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 | 著者 | Bohm, K, Schuetz, A, Roske, Y, Heinemann, U. | 登録日 | 2013-02-04 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Selective Inhibitors of the Protein Tyrosine Phosphatase Shp2 Block Cellular Motility and Growth of Cancer Cells in Vitro and in Vivo. Chemmedchem, 10, 2015
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7TGR
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![BU of 7tgr by Molmil](/molmil-images/mine/7tgr) | Structure of SARS-CoV-2 main protease in complex with GC376 | 分子名称: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 1,2-ETHANEDIOL, ... | 著者 | Esler, M.A, Shi, K, Aihara, H, Harris, R.S. | 登録日 | 2022-01-09 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M pro /3CL pro in Living Cells. Mbio, 13, 2022
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7TA0
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![BU of 7ta0 by Molmil](/molmil-images/mine/7ta0) | Human Ornithine Aminotransferase (hOAT) soaked with 5-aminovaleric acid | 分子名称: | 5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid, Ornithine aminotransferase, mitochondrial, ... | 著者 | Butrin, A, Liu, D. | 登録日 | 2021-12-20 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. J.Biol.Chem., 298, 2022
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1TG4
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![BU of 1tg4 by Molmil](/molmil-images/mine/1tg4) | Design of specific inhibitors of groupII phospholipase A2(PLA2): Crystal structure of the complex formed between russells viper PLA2 and designed peptide Phe-Leu-Ala-Tyr-Lys at 1.7A resolution | 分子名称: | FLAYK peptide, Phospholipase A2, SULFATE ION | 著者 | Singh, N, Somvanshi, R.K, Sharma, S, Dey, S, Perbandt, M, Betzel, C, Ethayathulla, A.S, Singh, T.P. | 登録日 | 2004-05-28 | 公開日 | 2004-06-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design of specific inhibitors of groupII phospholipase A2(PLA2): Crystal structure of the complex formed between russells viper PLA2 and designed peptide Phe-Leu-Ala-Tyr-Lys at 1.7A resolution TO BE PUBLISHED
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7SZZ
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![BU of 7szz by Molmil](/molmil-images/mine/7szz) | Structure of the smaller diameter PSMalpha3 nanotubes | 分子名称: | Phenol-soluble modulin PSM-alpha-3 | 著者 | Beltran, L.C, Kreutzberger, M.A, Wang, S, Egelman, E.H, Conticello, V.P. | 登録日 | 2021-11-29 | 公開日 | 2022-05-18 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids. Proc.Natl.Acad.Sci.USA, 119, 2022
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2J49
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![BU of 2j49 by Molmil](/molmil-images/mine/2j49) | Crystal structure of yeast TAF5 N-terminal domain | 分子名称: | TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 | 著者 | Romier, C, James, N, Birck, C, Cavarelli, J, Vivares, C, Collart, M.A, Moras, D. | 登録日 | 2006-08-28 | 公開日 | 2007-04-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure, Biochemical and Genetic Characterization of Yeast and E. Cuniculi Taf(II)5 N-Terminal Domain: Implications for TFIID Assembly. J.Mol.Biol., 368, 2007
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1TJE
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![BU of 1tje by Molmil](/molmil-images/mine/1tje) | Crystal structure of the editing domain of threonyl-tRNA synthetase | 分子名称: | Threonyl-tRNA synthetase | 著者 | Dock-Bregeon, A.C, Rees, B, Torres-Larios, A, Bey, G, Caillet, J, Moras, D. | 登録日 | 2004-06-04 | 公開日 | 2004-11-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Achieving Error-Free Translation; The Mechanism of Proofreading of Threonyl-tRNA Synthetase at Atomic Resolution. Mol.Cell, 16, 2004
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3EP3
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![BU of 3ep3 by Molmil](/molmil-images/mine/3ep3) | Human AdoMetDC D174N mutant with no putrescine bound | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYRUVIC ACID, S-adenosylmethionine decarboxylase alpha chain, ... | 著者 | Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E. | 登録日 | 2008-09-29 | 公開日 | 2008-12-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase. Biochemistry, 47, 2008
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7T8U
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1TL7
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![BU of 1tl7 by Molmil](/molmil-images/mine/1tl7) | Complex Of Gs- With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With 2'(3')-O-(N-methylanthraniloyl)-guanosine 5'-triphosphate and Mn | 分子名称: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase, ... | 著者 | Mou, T.C, Gille, A, Seifert, R.J, Sprang, S.R. | 登録日 | 2004-06-09 | 公開日 | 2004-12-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate. J.Biol.Chem., 280, 2005
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7T0X
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![BU of 7t0x by Molmil](/molmil-images/mine/7t0x) | Structure of the larger diameter PSMalpha3 nanotube | 分子名称: | Phenol-soluble modulin PSM-alpha-3 | 著者 | Kreutzberger, M.A, Wang, S, Beltran, L.C, Egelman, E.H, Conticello, V.P. | 登録日 | 2021-11-30 | 公開日 | 2022-05-18 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SSG
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![BU of 7ssg by Molmil](/molmil-images/mine/7ssg) | Mfd DNA complex | 分子名称: | DNA (5'-D(P*TP*GP*GP*CP*GP*GP*CP*GP*AP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*GP*CP*CP*TP*CP*GP*CP*TP*GP*CP*CP*A)-3'), Transcription-repair-coupling factor | 著者 | Oakley, A.J, Xu, Z.-Q. | 登録日 | 2021-11-11 | 公開日 | 2022-05-25 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Mechanism of transcription modulation by the transcription-repair coupling factor. Nucleic Acids Res., 50, 2022
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1SV6
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![BU of 1sv6 by Molmil](/molmil-images/mine/1sv6) | Crystal structure of 2-hydroxypentadienoic acid hydratase from Escherichia Coli | 分子名称: | 2-keto-4-pentenoate hydratase | 著者 | Fedorov, A.A, Fedorov, E.V, Sharp, A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2004-03-28 | 公開日 | 2004-06-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of 2-hydroxypentadienoic acid hydratase from Escherichia Coli To be Published
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1K58
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![BU of 1k58 by Molmil](/molmil-images/mine/1k58) | Crystal Structure of Human Angiogenin Variant D116H | 分子名称: | Angiogenin | 著者 | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | 登録日 | 2001-10-10 | 公開日 | 2002-03-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Biochemistry, 41, 2002
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6VK9
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![BU of 6vk9 by Molmil](/molmil-images/mine/6vk9) | Cryo-EM structure of PilA-N/C from Geobacter sulfurreducens | 分子名称: | Geopilin domain 1 protein, Geopilin domain 2 protein | 著者 | Gu, Y, Srikanth, V, Malvankar, N.S, Samatey, F.A. | 登録日 | 2020-01-19 | 公開日 | 2021-07-07 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of Geobacter pili reveals secretory rather than nanowire behaviour Nature, 597, 2021
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2IEB
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![BU of 2ieb by Molmil](/molmil-images/mine/2ieb) | Crystal Structure of Isoniazid-resistant S94A ENOYL-ACP(COA) Reductase Mutant Enzyme from MYCOBACTERIUM TUBERCULOSIS in Complex with NADH-INH | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE | 著者 | Dias, M.V.B, Prado, A.M.X, Vasconcelos, I.B, Fadel, V, Basso, L.A, Santos, D.S, Azevedo Jr, W.F. | 登録日 | 2006-09-18 | 公開日 | 2007-07-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis. J.Struct.Biol., 159, 2007
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5KP0
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![BU of 5kp0 by Molmil](/molmil-images/mine/5kp0) | Recognition and targeting mechanisms by chaperones in flagella assembly and operation | 分子名称: | Flagellar protein FliT,Flagellum-specific ATP synthase | 著者 | Khanra, N.K, Rossi, P, Economou, A, Kalodimos, C.G. | 登録日 | 2016-07-01 | 公開日 | 2016-08-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition and targeting mechanisms by chaperones in flagellum assembly and operation. Proc.Natl.Acad.Sci.USA, 113, 2016
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2IED
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![BU of 2ied by Molmil](/molmil-images/mine/2ied) | CRYSTAL STRUCTURE of ISONIAZID-RESISTANT S94A ENOYL-ACP(COA) REDUCTASE MUTANT ENZYME FROM MYCOBACTERIUM TUBERCULOSIS UNCOMPLEXED | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH] | 著者 | Dias, M.V.B, Prado, A.M.X, Vasconcelos, I.B, Fadel, V, Basso, L.A, Santos, D.S, Azevedo Jr, W.F. | 登録日 | 2006-09-18 | 公開日 | 2007-07-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis. J.Struct.Biol., 159, 2007
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8A97
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![BU of 8a97 by Molmil](/molmil-images/mine/8a97) | ROOM TEMPERATURE CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) UNDER XENON PRESSURE (30 bar) | 分子名称: | 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, D(-)-TARTARIC ACID, XENON | 著者 | Bui, S, Prange, T, Steiner, R.A. | 登録日 | 2022-06-27 | 公開日 | 2023-07-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.897 Å) | 主引用文献 | Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the alpha / beta-hydrolase fold. Chem Sci, 14, 2023
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2IOQ
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![BU of 2ioq by Molmil](/molmil-images/mine/2ioq) | |
6WA4
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![BU of 6wa4 by Molmil](/molmil-images/mine/6wa4) | Solution NMR structure of the unmyristoylated feline immunodeficiency virus matrix protein | 分子名称: | Matrix protein | 著者 | Brown, J.B, Summers, H.R, Brown, L.A, Marchant, J, Canova, P.N, O'Hern, C.T, Abbott, S.T, Nyaunu, C, Maxwell, S, Johnson, T, Moser, M.B, Carter, H, Ablan, S, Freed, E.O, Summers, M.F. | 登録日 | 2020-03-24 | 公開日 | 2020-07-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus. J.Mol.Biol., 432, 2020
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3ESA
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![BU of 3esa by Molmil](/molmil-images/mine/3esa) | cut-1b; NCN-Pt-Pincer-Cutinase Hybrid | 分子名称: | (2,6-bis[(dimethylamino-kappaN)methyl]-4-{3-[(S)-ethoxy(4-nitrophenoxy)phosphoryl]propyl}phenyl-kappaC~1~)(chloro)platinum(2+), Cutinase 1 | 著者 | Rutten, L, Mannie, J.P.B.A, Lutz, M, Gros, P. | 登録日 | 2008-10-05 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids Chemistry, 15, 2009
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7TBK
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![BU of 7tbk by Molmil](/molmil-images/mine/7tbk) | Composite structure of the dilated human nuclear pore complex (NPC) symmetric core generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | 分子名称: | NUP107 CTD, NUP107 NTD, NUP133, ... | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (37 Å) | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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2IS7
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![BU of 2is7 by Molmil](/molmil-images/mine/2is7) | Crystal Structure of Aldose Reductase complexed with Dichlorophenylacetic acid | 分子名称: | (2,6-DICHLOROPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Harrison, D.H.T, Milne, A, Brownlee, J.M. | 登録日 | 2006-10-16 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes. Bioorg.Chem., 34, 2006
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3ERM
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![BU of 3erm by Molmil](/molmil-images/mine/3erm) | |