8A93
 
 | | Complex of RecF-RecR-DNA from Thermus thermophilus. | | 分子名称: | DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ... | | 著者 | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | | 登録日 | 2022-06-27 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
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4RG3
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1TBT
 | | Effect of Shuttle Location and pH Environment on H+ Transfer in Human Carbonic Anhydrase II | | 分子名称: | Carbonic anhydrase II, ZINC ION | | 著者 | Fisher, Z, Hernandez Prada, J.A, Tu, C.K, Duda, D, Yoshioka, C, An, H, Govindasamy, L, Silverman, D.N, McKenna, R. | | 登録日 | 2004-05-20 | | 公開日 | 2005-01-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II.
Biochemistry, 44, 2005
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6IVL
 | | Crystal structure of a membrane protein L259A | | 分子名称: | ACETIC ACID, CHLORIDE ION, Ibestrophin, ... | | 著者 | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | | 登録日 | 2018-12-04 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
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3EJP
 | | Golgi alpha-Mannosidase II in complex with 5-substituted swainsonine analog: (5R)-5-[2'-oxo-2'-(phenyl)ethyl]-swainsonine | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1-phenyl-2-[(1S,2R,5R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizin-5-yl]ethanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kuntz, D.A, Rose, D.R. | | 登録日 | 2008-09-18 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Structural Investigation of the Binding of 5-Substituted Swainsonine Analogues to Golgi alpha-Mannosidase II.
Chembiochem, 11, 2010
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3EO3
 | | Crystal structure of the N-acetylmannosamine kinase domain of human GNE protein | | 分子名称: | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, UNKNOWN ATOM OR ION, ZINC ION | | 著者 | Nedyalkova, L, Tong, Y, Rabeh, W.M, Hong, B, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-09-26 | | 公開日 | 2008-10-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Crystal structure of the N-acetylmannosamine kinase domain of GNE.
Plos One, 4, 2009
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4RGI
 | | Crystal Structure of KTSC Domain Protein YPO2434 from Yersinia pestis | | 分子名称: | GLYCEROL, SULFATE ION, Uncharacterized protein | | 著者 | Kim, Y, Chhor, G, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-09-30 | | 公開日 | 2014-12-31 | | 実験手法 | X-RAY DIFFRACTION (1.732 Å) | | 主引用文献 | Crystal Structure of KTSC Domain Protein YPO2434 from Yersinia pestis
To be Published
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3ZKO
 | | The structure of ''breathing'' dengue virus. | | 分子名称: | ENVELOPE GLYCOPROTEIN | | 著者 | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Lee, S, Wang, J, Lok, S.M. | | 登録日 | 2013-01-24 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (13.7 Å) | | 主引用文献 | Structural Changes of Dengue Virus When Exposed to 37 Degrees C.
J.Virol., 87, 2013
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7T9H
 | | HIV Integrase in complex with Compound-15 | | 分子名称: | (2S)-tert-butoxy[2-methyl-4-(4-methylphenyl)quinolin-3-yl]acetic acid, Integrase, MAGNESIUM ION | | 著者 | Khan, J.A, Lewis, H, Kish, K. | | 登録日 | 2021-12-19 | | 公開日 | 2022-04-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Design, Synthesis, and Preclinical Profiling of GSK3739936 (BMS-986180), an Allosteric Inhibitor of HIV-1 Integrase with Broad-Spectrum Activity toward 124/125 Polymorphs.
J.Med.Chem., 65, 2022
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3ZKL
 | | Structure of the xylo-oligosaccharide specific solute binding protein from Bifidobacterium animalis subsp. lactis Bl-04 in complex with xylotriose | | 分子名称: | PENTAETHYLENE GLYCOL, PUTATIVE SUGAR TRANSPORTER SOLUTE-BINDING PROTEIN, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | | 著者 | Ejby, M, Vujicic-Zagar, A, Fredslund, F, Svensson, B, Slotboom, D.J, Abou Hachem, M. | | 登録日 | 2013-01-23 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | | 主引用文献 | Structural Basis for Arabinoxylo-Oligosaccharide Capture by the Probiotic Bifidobacterium Animalis Subsp. Lactis Bl-04
Mol.Microbiol., 90, 2013
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2IE0
 | | Crystal Structure of Isoniazid-resistant I21V Enoyl-ACP(COA) Reductase Mutant Enzyme From MYCOBACTERIUM TUBERCULOSIS in Complex with NADH-INH | | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE | | 著者 | Dias, M.V.B, Prado, A.M.X, Vasconceles, I.B, Fadel, F, Basso, L.A, Santos, D.S, Azevedo Jr, W.F. | | 登録日 | 2006-09-15 | | 公開日 | 2007-07-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis.
J.Struct.Biol., 159, 2007
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5KC7
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5KJP
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3ZM0
 | | Catalytic domain of human SHP2 | | 分子名称: | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 | | 著者 | Bohm, K, Schuetz, A, Roske, Y, Heinemann, U. | | 登録日 | 2013-02-04 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Selective Inhibitors of the Protein Tyrosine Phosphatase Shp2 Block Cellular Motility and Growth of Cancer Cells in Vitro and in Vivo.
Chemmedchem, 10, 2015
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7SWS
 | | Crystal structure of the chromoprotein amilCP | | 分子名称: | BROMIDE ION, CHLORIDE ION, Chromoprotein amilCP | | 著者 | Caputo, A.T, Newman, J, Scott, C, Ahmed, H. | | 登録日 | 2021-11-21 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.642 Å) | | 主引用文献 | Over the rainbow: structural characterization of the chromoproteins gfasPurple, amilCP, spisPink and eforRed.
Acta Crystallogr D Struct Biol, 78, 2022
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1JDO
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7SXK
 | | Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length | | 分子名称: | Portal protein | | 著者 | Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | | 登録日 | 2021-11-23 | | 公開日 | 2022-04-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
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1T48
 | | Allosteric Inhibition of Protein Tyrosine Phosphatase 1B | | 分子名称: | 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID DIMETHYLAMIDE, Protein-tyrosine phosphatase, non-receptor type 1 | | 著者 | Wiesmann, C, Barr, K.J, Kung, J, Zhu, J, Shen, W, Fahr, B.J, Zhong, M, Erlanson, D.A, Taylor, L, Randal, M, McDowell, R.S, Hansen, S.K. | | 登録日 | 2004-04-28 | | 公開日 | 2004-07-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Allosteric inhibition of protein tyrosine phosphatase 1B
Nat.Struct.Mol.Biol., 11, 2004
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1T4Y
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4RGM
 | | Structure of Staphylococcal Enterotoxin B bound to the neutralizing antibody 20B1 | | 分子名称: | 20B1 heavy chain, 20B1 light chain, Enterotoxin type B | | 著者 | Franklin, M.C, Dutta, K, Varshney, A.K, Goger, M.J, Fries, B.C. | | 登録日 | 2014-09-30 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.689 Å) | | 主引用文献 | Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
J.Biol.Chem., 290, 2015
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1T5D
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6J5G
 | | Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein | | 分子名称: | Envelope protein E, antibody heavy chain, antibody light chain | | 著者 | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.291 Å) | | 主引用文献 | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus.
J. Virol., 93, 2019
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4RG1
 | | Methyltransferase domain of C9orf114 | | 分子名称: | C9orf114, POLYETHYLENE GLYCOL (N=34), S-1,2-PROPANEDIOL, ... | | 著者 | Dong, A, Zeng, H, Walker, J.R, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2014-09-29 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | The Crystal Structure of Human C9orf114 in complex with S-adenosyl-homocysteine
To be Published
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3EPA
 | | Human AdoMetDC E178Q mutant complexed with putrescine | | 分子名称: | 1,4-DIAMINOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYRUVIC ACID, ... | | 著者 | Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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4RGN
 | | Structure of Staphylococcal Enterotoxin B bound to two neutralizing antibodies, 14G8 and 6D3 | | 分子名称: | 14G8 heavy chain, 14G8 light chain, 6D3 heavy chain, ... | | 著者 | Franklin, M.C, Dutta, K, Varshney, A.K, Goger, M.J, Fries, B.C. | | 登録日 | 2014-09-30 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | | 主引用文献 | Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
J.Biol.Chem., 290, 2015
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