4RGN

Structure of Staphylococcal Enterotoxin B bound to two neutralizing antibodies, 14G8 and 6D3

Summary for 4RGN

• Entry DOI: 10.2210/pdb4rgn/pdb
• Related: 4RGM 4RGO
• Descriptor: Enterotoxin type B, 14G8 heavy chain, 14G8 light chain, ... (5 entities in total)
• Functional Keywords: neutralizing antibody, staphylococcal enterotoxin b, toxin-immune system complex, toxin/immune system
• Biological source: Staphylococcus aureus; More
• Cellular location: Secreted: P01552
• Total number of polymer chains: 10
• Total formula weight: 248713.14

Authors

Franklin, M.C.,Dutta, K.,Varshney, A.K.,Goger, M.J.,Fries, B.C. (deposition date: 2014-09-30, release date: 2015-01-21, Last modification date: 2023-09-20)

• Primary citation: Dutta, K.,Varshney, A.K.,Franklin, M.C.,Goger, M.,Wang, X.,Fries, B.C.; Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.; J.Biol.Chem., 290:6715-6730, 2015; PubMed: 25572397; DOI: 10.1074/jbc.M114.630715

Experimental method

X-RAY DIFFRACTION (2.698 Å)