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PDB: 89035 件

4V95
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Crystal structure of YAEJ bound to the 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Gagnon, M.G, Seetharaman, S.V, Bulkley, D.P, Steitz, T.A.
登録日2012-01-27
公開日2014-07-09
最終更新日2018-07-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome.
Science, 335, 2012
4WEG
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influenza virus neuraminidase N9 in complex 2,3-difluorosialic acid
分子名称: (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid, (3R,4R,5R,6R)-5-(acetylamino)-3-fluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4,5,6-tetrahydropyranium-2-carboxylate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Streltsov, V.A, Pilling, P, Barrett, S, McKimm-Breschkin, J.
登録日2014-09-10
公開日2015-09-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Catalytic mechanism and novel receptor binding sites of human parainfluenza virus type 3 hemagglutinin-neuraminidase (hPIV3 HN)
Antiviral Res., 123, 2015
8S9X
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CRISPR-Cas type III-D effector complex bound to self-target RNA in a post-cleavage state
分子名称: CRISPR RNA, Cas10, Cas7-2x, ...
著者Schwartz, E.A, Taylor, D.W.
登録日2023-03-30
公開日2024-04-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
Nat Commun, 15, 2024
5E56
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Crystal structure of mouse CTLA-4
分子名称: Cytotoxic T-lymphocyte protein 4, SODIUM ION
著者Fedorov, A.A, Fedorov, E.V, SAMANTA, D, Bonanno, J.B, Almo, S.C.
登録日2015-10-07
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.504 Å)
主引用文献Crystal structure of mouse CTLA-4
To Be Published
6DVH
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Lactate Monooxygenase from Mycobacterium smegmatis - C203A mutant
分子名称: FLAVIN MONONUCLEOTIDE, Lactate 2-monooxygenase, SULFATE ION
著者Kean, K.M, Karplus, P.A.
登録日2018-06-23
公開日2018-10-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and role for active site lid of lactate monooxygenase from Mycobacterium smegmatis.
Protein Sci., 28, 2019
3L26
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Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA
分子名称: CHLORIDE ION, MAGNESIUM ION, Polymerase cofactor VP35, ...
著者Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K.
登録日2009-12-14
公開日2010-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
4FKG
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Crystal structure of the cdk2 in complex with aminopyrazole inhibitor
分子名称: 4-[(5-cyclopropyl-1H-pyrazol-3-yl)carbamoyl]benzoic acid, Cyclin-dependent kinase 2
著者Kang, Y.N, Stuckey, J.A.
登録日2012-06-13
公開日2013-05-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Crystal structure of the cdk2 in complex with aminopyrazole inhibitor
To be Published
6DH3
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Crystal structure of HIV-1 Protease NL4-3 V82I Mutant in complex with darunavir
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease, SULFATE ION
著者Lockbaum, G.J, Schiffer, C.A.
登録日2018-05-18
公開日2018-12-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.908 Å)
主引用文献Structural Adaptation of Darunavir Analogues against Primary Mutations in HIV-1 Protease.
ACS Infect Dis, 5, 2019
3KVT
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TETRAMERIZATION DOMAIN FROM AKV3.1 (SHAW-SUBFAMILY) VOLTAGE-GATED POTASSIUM CHANNEL
分子名称: POTASSIUM CHANNEL PROTEIN SHAW, ZINC ION
著者Bixby, K.A, Nanao, M.H, Shen, N.V, Kreusch, A, Bellamy, H, Pfaffinger, P.J, Choe, S.
登録日1998-09-25
公開日1999-01-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels.
Nat.Struct.Biol., 6, 1999
5E7D
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Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand
分子名称: (2E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one, 1,2-ETHANEDIOL, Protein polybromo-1
著者Filippakopoulos, P, Picaud, S, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Owen, D, Knapp, S, Structural Genomics Consortium (SGC)
登録日2015-10-12
公開日2016-10-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand
To Be Published
1I43
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CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR PPCA
分子名称: 3-(PHOSPHONOMETHYL)PYRIDINE-2-CARBOXYLIC ACID, CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE
著者Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T.
登録日2001-02-19
公開日2001-09-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
2GA0
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Variable Small Protein 1 of Borrelia turicatae (VspA or Vsp1)
分子名称: NICKEL (II) ION, surface protein VspA
著者Lawson, C.L, Yung, B.H, Barbour, A.G, Zuckert, W.R.
登録日2006-03-07
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of neurotropism-associated variable surface protein 1 (Vsp1) of Borrelia turicatae.
J.Bacteriol., 188, 2006
1I6Z
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BAG DOMAIN OF BAG1 COCHAPERONE
分子名称: BAG-FAMILY MOLECULAR CHAPERONE REGULATOR-1
著者Briknarova, K, Takayama, S, Brive, L, Havert, M.L, Knee, D.A, Velasco, J, Homma, S, Cabezas, E, Stuart, J, Hoyt, D.W, Satterthwait, A.C, Llinas, M, Reed, J.C, Ely, K.R.
登録日2001-03-06
公開日2001-09-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein.
Nat.Struct.Biol., 8, 2001
2GBZ
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The Crystal Structure of XC847 from Xanthomonas campestris: a 3-5 Oligoribonuclease of DnaQ fold family with a Novel Opposingly-Shifted Helix
分子名称: MAGNESIUM ION, Oligoribonuclease
著者Chin, K.H, Yang, C.Y, Chou, C.C, Wang, A.H.J, Chou, S.H.
登録日2006-03-12
公開日2007-01-16
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of XC847 from Xanthomonas campestris: a 3'-5' oligoribonuclease of DnaQ fold family with a novel opposingly shifted helix
Proteins, 65, 2006
3LL7
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Crystal structure of putative methyltransferase PG_1098 from Porphyromonas gingivalis W83
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Putative methyltransferase
著者Chang, C, Chhor, G, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2010-01-28
公開日2010-02-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of putative methyltransferase PG_1098 from Porphyromonas gingivalis W83
To be Published
6DQP
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Crystal structure of SsuE FMN reductase Delta118 mutant in apo form
分子名称: FMN reductase (NADPH), GLYCEROL
著者McFarlane, J.S, Ellis, H.R, Lamb, A.L.
登録日2018-06-11
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.546 Å)
主引用文献Not as easy as pi : An insertional residue does not explain the pi-helix gain-of-function in two-component FMN reductases.
Protein Sci., 28, 2019
2GB0
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Monomeric sarcosine oxidase: structure of a covalently flavinylated amine oxidizing enzyme
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Monomeric sarcosine oxidase, ...
著者Trickey, P, Wagner, M.A, Jorns, M.S, Mathews, F.S.
登録日2006-03-09
公開日2006-03-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Monomeric Sarcosine Oxidase: Structure of a Covalently Flavinylated Amine Oxidizing Enzyme
Structure, 7, 1999
6DJP
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Integrin alpha-v beta-8 in complex with the Fabs 8B8 and 68
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 68 heavy chain Fab, ...
著者Cormier, A, Campbell, M.G, Nishimura, S.L, Cheng, Y.
登録日2018-05-25
公開日2018-07-25
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM structure of the alpha v beta 8 integrin reveals a mechanism for stabilizing integrin extension.
Nat. Struct. Mol. Biol., 25, 2018
2GIA
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Crystal structures of trypanosoma bruciei MRP1/MRP2
分子名称: ACETIC ACID, mitochondrial RNA-binding protein 1, mitochondrial RNA-binding protein 2
著者Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J.
登録日2006-03-28
公開日2006-09-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism.
Cell(Cambridge,Mass.), 126, 2006
1I48
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CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR CTCPO
分子名称: CARBOXYMETHYLTHIO-3-(3-CHLOROPHENYL)-1,2,4-OXADIAZOL, CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE
著者Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T.
登録日2001-02-20
公開日2001-09-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
6DLZ
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Open state GluA2 in complex with STZ after micelle signal subtraction
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit
著者Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I.
登録日2018-06-04
公開日2018-08-22
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.
Neuron, 99, 2018
4UQY
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Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes
分子名称: HSIB1, HSIE1
著者Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A.
登録日2014-06-25
公開日2014-10-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes.
J.Biol.Chem., 289, 2014
3LH1
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Q191A mutant of the DegS-deltaPDZ
分子名称: Protease degS
著者Sohn, J, Grant, R.A, Sauer, R.T.
登録日2010-01-21
公開日2010-08-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.507 Å)
主引用文献Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
4URG
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Crystal Structure of GGDEF domain from T.maritima (active-like dimer)
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DIGUANYLATE CYCLASE
著者Deepthi, A, Liew, C.W, Liang, Z.X, Swaminathan, K, Lescar, J.
登録日2014-06-30
公開日2014-10-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
2G3I
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Structure of S.olivaceoviridis xylanase Q88A/R275A mutant
分子名称: PHOSPHATE ION, Xylanase
著者Diertavitian, S, Kaneko, S, Fujimoto, Z, Kuno, A, Johansson, E, Lo Leggio, L.
登録日2006-02-20
公開日2007-03-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based engineering of glucose specificity in a family 10 xylanase from Streptomyces olivaceoviridis E-86
PROCESS BIOCHEM, 47, 2012

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