2GB0

Monomeric sarcosine oxidase: structure of a covalently flavinylated amine oxidizing enzyme

Replaces:  1L9FReplaces:  1B3M

Summary for 2GB0

• Entry DOI: 10.2210/pdb2gb0/pdb
• Descriptor: Monomeric sarcosine oxidase, PHOSPHATE ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: flavoprotein oxidase, oxidoreductase
• Biological source: Bacillus sp.
• Cellular location: Cytoplasm: P40859
• Total number of polymer chains: 2
• Total formula weight: 88224.60

Authors

Trickey, P.,Wagner, M.A.,Jorns, M.S.,Mathews, F.S. (deposition date: 2006-03-09, release date: 2006-03-21, Last modification date: 2024-10-09)

Primary citation

Trickey, P.,Wagner, M.A.,Jorns, M.S.,Mathews, F.S.
Monomeric Sarcosine Oxidase: Structure of a Covalently Flavinylated Amine Oxidizing Enzyme
Structure, 7:331-345, 1999

PubMed Abstract: Monomeric sarcosine oxidases (MSOXs) are among the simplest members of a recently recognized family of eukaryotic and prokaryotic enzymes that catalyze similar oxidative reactions with various secondary or tertiary amino acids and contain covalently bound flavins. Other members of this family include heterotetrameric sarcosine oxidase, N-methyltryptophan oxidase and pipecolate oxidase. Mammalian sarcosine dehydrogenase and dimethylglycine dehydrogenase may be more distantly related family members.

PubMed: 10368302
DOI: 10.1016/S0969-2126(99)80043-4

Experimental method

X-RAY DIFFRACTION (1.85 Å)