4U5X
 
 | | Structure of plant small GTPase OsRac1 complexed with the non-hydrolyzable GTP analog GMPPNP | | 分子名称: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Ohki, I, Kosami, K, Fujiwara, T, Nakagawa, A, Shimamoto, K, Kojima, C. | | 登録日 | 2014-07-25 | | 公開日 | 2014-08-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Crystal Structure of the Plant Small GTPase OsRac1 Reveals Its Mode of Binding to NADPH Oxidase
J.Biol.Chem., 289, 2014
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8P04
 | | Crystal structure of human CLK1 in complex with Leucettinib-92 | | 分子名称: | (4~{Z})-2-(1-adamantylamino)-4-(1,3-benzothiazol-6-ylmethylidene)-1~{H}-imidazol-5-one, Dual specificity protein kinase CLK1 | | 著者 | Kraemer, A, Schroeder, M, Meijer, L, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2023-05-09 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Leucettinibs, a Class of DYRK/CLK Kinase Inhibitors Inspired by the Marine Sponge Natural Product Leucettamine B.
J.Med.Chem., 66, 2023
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3JCS
 | | 2.8 Angstrom cryo-EM structure of the large ribosomal subunit from the eukaryotic parasite Leishmania | | 分子名称: | 26S alpha ribosomal RNA, 26S delta ribosomal RNA, 26S epsilon ribosomal RNA, ... | | 著者 | Shalev-Benami, M, Zhang, Y, Matzov, D, Halfon, Y, Zackay, A, Rozenberg, H, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G. | | 登録日 | 2016-01-21 | | 公開日 | 2016-07-20 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | 2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania.
Cell Rep, 16, 2016
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7WIO
 | | NMR structure of N-terminal domain of Triconephila clavipes of major ampullate spidroin 1 | | 分子名称: | Major ampullate spidroin 1A | | 著者 | Oktaviani, N.A, Malay, A.D, Matsugami, A, Hayashi, F, Numata, K. | | 登録日 | 2022-01-04 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Unusual p K a Values Mediate the Self-Assembly of Spider Dragline Silk Proteins.
Biomacromolecules, 24, 2023
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5HR4
 | | Structure of Type IIL restriction-modification enzyme MmeI in complex with DNA has implications for engineering of new specificities | | 分子名称: | CALCIUM ION, DNA (5'-D(P*GP*TP*TP*AP*TP*GP*TP*CP*GP*GP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*CP*CP*GP*AP*CP*AP*TP*AP*AP*C)-3'), ... | | 著者 | Callahan, S.J, Luyten, Y.A, Gupta, Y.K, Wilson, G.G, Roberts, R.J, Morgan, R.D, Aggarwal, A.K. | | 登録日 | 2016-01-22 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.5964 Å) | | 主引用文献 | Structure of Type IIL Restriction-Modification Enzyme MmeI in Complex with DNA Has Implications for Engineering New Specificities.
Plos Biol., 14, 2016
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4U6Z
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1A4Y
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8UCF
 | | Thermophilic RNA Ligase from Palaeococcus pacificus K238G | | 分子名称: | ATP dependent DNA ligase, GLYCEROL, MAGNESIUM ION | | 著者 | Rousseau, M.D, Hicks, J.L, Oulavallickal, T, Williamson, A, Arcus, V.L, Patrick, M.W. | | 登録日 | 2023-09-26 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus.
Nucleic Acids Res., 52, 2024
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6G6M
 | | Crystal structure of the computationally designed Tako8 protein in P42212 | | 分子名称: | SULFATE ION, Tako8 | | 著者 | Noguchi, H, Addy, C, Simoncini, D, Van Meervelt, L, Schiex, T, Zhang, K.Y.J, Tame, J.R.H, Voet, A.R.D. | | 登録日 | 2018-04-01 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Computational design of symmetrical eight-bladed beta-propeller proteins.
IUCrJ, 6, 2019
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5TLN
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8BD2
 | | Calcium-bound Calmodulin variant G113R | | 分子名称: | CALCIUM ION, Calmodulin-3 | | 著者 | Wimmer, R, Holler, C.V, Petersson, N.M, Iwai, H, Niemelae, M.A, Brohus, M, Overgaard, M.T. | | 登録日 | 2022-10-18 | | 公開日 | 2023-11-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca 2+ coordinating residues.
Cell Calcium, 117, 2023
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5HTG
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6CH6
 | | Dehaloperoxidase B in complex with substrate 2,4-dimethoxyphenol | | 分子名称: | 2,4-dimethoxyphenol, Dehaloperoxidase B, GLYCEROL, ... | | 著者 | de Serrano, V.S, Carey, L.M, Ghiladi, R.A. | | 登録日 | 2018-02-22 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Peroxidase versus Peroxygenase Activity: Substrate Substituent Effects as Modulators of Enzyme Function in the Multifunctional Catalytic Globin Dehaloperoxidase.
Biochemistry, 57, 2018
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4U8D
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1ADS
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6YZC
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6FN1
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6RL9
 | | Human Carbonic Anhydrase II in complex with 4-Aminobenzenesulfonamide | | 分子名称: | (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, MERCURY (II) ION, ... | | 著者 | Gloeckner, S, Heine, A, Klebe, G. | | 登録日 | 2019-05-01 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II.
Biomolecules, 10, 2020
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5TH6
 | | Structure determination of a potent, selective antibody inhibitor of human MMP9 (apo MMP9) | | 分子名称: | CALCIUM ION, Matrix metalloproteinase-9,Matrix metalloproteinase-9, ZINC ION | | 著者 | Appleby, T.C, Greenstein, A.E, Kwon, H.J. | | 登録日 | 2016-09-29 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
J. Biol. Chem., 292, 2017
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6CDF
 | | Human CtBP1 (28-378) | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C-terminal-binding protein 1, CALCIUM ION, ... | | 著者 | Royer, W.E, Bellesis, A.G. | | 登録日 | 2018-02-08 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Assembly of human C-terminal binding protein (CtBP) into tetramers.
J. Biol. Chem., 293, 2018
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6CDW
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6G8R
 | | SP140 PHD-Bromodomain complex with scFv | | 分子名称: | 1,2-ETHANEDIOL, Nuclear body protein SP140, ZINC ION, ... | | 著者 | Fairhead, M, Graslund, S, Strain-Damerell, C, Picaud, S.S, Pike, A.C.W, Pinkas, D.M, Wigren, E, Preger, C, Persson Lotsholm, H, Ossipova, E, Filippakopoulos, P, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Structural Genomics Consortium (SGC) | | 登録日 | 2018-04-09 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | SP140 PHD-Bromodomain complex with scFv
To Be Published
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5J5F
 | | X-Ray Crystal Structure of Acetylcholine Binding Protein (AChBP) in Complex with N4,N4-bis[(pyridin-2-yl)methyl]-6-(thiophen-3-yl)pyrimidine-2,4-diamine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine-binding protein, DIMETHYL SULFOXIDE, ... | | 著者 | Kaczanowska, K, Camacho Hernandez, G.A, Harel, M, Taylor, P. | | 登録日 | 2016-04-02 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins.
J. Am. Chem. Soc., 139, 2017
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7VY2
 | | STRUCTURE OF PHOTOSYNTHETIC LH1-RC SUPER-COMPLEX OF RHODOBACTER SPHAEROIDES DIMER | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Antenna pigment protein alpha chain, Antenna pigment protein beta chain, ... | | 著者 | Tani, K, Kanno, R, Kawamura, S, Kikuchi, R, Nagashima, K.V.P, Hall, M, Takahashi, A, Yu, L.-J, Kimura, Y, Madigan, M.T, Mizoguchi, A, Humbel, B.M, Wang-Otomo, Z.-Y. | | 登録日 | 2021-11-13 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Asymmetric structure of the native Rhodobacter sphaeroides dimeric LH1-RC complex.
Nat Commun, 13, 2022
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8OSI
 | | Genetically encoded green ratiometric calcium indicator FNCaMP in calcium-bound state | | 分子名称: | CALCIUM ION, mNeonGreen,Calmodulin,Contig An16c0100, genomic contig | | 著者 | Varfolomeeva, L.A, Boyko, K.M, Nikolaeva, A.Y, Subach, O.M, Subach, F.V. | | 登録日 | 2023-04-19 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | FNCaMP, ratiometric green calcium indicator based on mNeonGreen protein.
Biochem.Biophys.Res.Commun., 665, 2023
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