4FAW
| Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+ and a hydrolyzed oligonucleotide fragment | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-R(*A*UP*UP*UP*AP*UP*UP*A)-3', Group IIC intron, ... | 著者 | Marcia, M, Pyle, A.M. | 登録日 | 2012-05-22 | 公開日 | 2012-11-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Visualizing Group II Intron Catalysis through the Stages of Splicing. Cell(Cambridge,Mass.), 151, 2012
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8C3G
| Crystal structure of DYRK1A in complex with AZ191 | 分子名称: | 1,2-ETHANEDIOL, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine, ... | 著者 | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | 登録日 | 2022-12-23 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural perspective on the design of selective DYRK1B inhibitors To Be Published
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5HP5
| Srtucture of human peptidylarginine deiminase type I (PAD1) | 分子名称: | CALCIUM ION, Protein-arginine deiminase type-1 | 著者 | Unno, M, Nagai, A, Saijo, S, Shimizu, N, Kinjo, S, Mashimo, R, Kizawa, K, Takahara, H. | 登録日 | 2016-01-20 | 公開日 | 2016-07-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.198 Å) | 主引用文献 | Monomeric Form of Peptidylarginine Deiminase Type I Revealed by X-ray Crystallography and Small-Angle X-ray Scattering J.Mol.Biol., 428, 2016
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4ZFI
| Structure of Mdm2 with low molecular weight inhibitor | 分子名称: | (5S)-3,5-bis(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-5-hydroxy-1-methyl-1,5-dihydro-2H-pyrrol-2-one, E3 ubiquitin-protein ligase Mdm2 | 著者 | Zak, K.M, Twarda-Clapa, A, Wrona, E.M, Grudnik, P, Dubin, G, Holak, T.A. | 登録日 | 2015-04-21 | 公開日 | 2016-10-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction. ACS Chem. Biol., 11, 2016
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5YVV
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5AFN
| alpha7-AChBP in complex with lobeline and fragment 5 | 分子名称: | (4R)-4-(2-phenylethyl)pyrrolidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE-BINDING PROTEIN, ... | 著者 | Spurny, R, Debaveye, S, Farinha, A, Veys, K, Gossas, T, Atack, J, Bertrand, D, Kemp, J, Vos, A, Danielson, U.H, Tresadern, G, Ulens, C. | 登録日 | 2015-01-22 | 公開日 | 2015-05-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.149 Å) | 主引用文献 | Molecular Blueprint of Allosteric Binding Sites in a Homologue of the Agonist-Binding Domain of the Alpha7 Nicotinic Acetylcholine Receptor. Proc.Natl.Acad.Sci.USA, 112, 2015
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6ME2
| XFEL crystal structure of human melatonin receptor MT1 in complex with ramelteon | 分子名称: | DI(HYDROXYETHYL)ETHER, N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide, OLEIC ACID, ... | 著者 | Stauch, B, Johansson, L.C, McCorvy, J.D, Patel, N, Han, G.W, Gati, C, Batyuk, A, Ishchenko, A, Brehm, W, White, T.A, Michaelian, N, Madsen, C, Zhu, L, Grant, T.D, Grandner, J.M, Olsen, R.H.J, Tribo, A.R, Weierstall, U, Roth, B.L, Katritch, V, Liu, W, Cherezov, V. | 登録日 | 2018-09-05 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of ligand recognition at the human MT1melatonin receptor. Nature, 569, 2019
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1ADJ
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6G1N
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6IFF
| Crystal structure of M1 zinc metallopeptidase E323A mutant from Deinococcus radiodurans | 分子名称: | SODIUM ION, TYROSINE, ZINC ION, ... | 著者 | Agrawal, R, Kumar, A, Kumar, A, Gaur, N.K, Makde, R.D. | 登録日 | 2018-09-20 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase. Int.J.Biol.Macromol., 147, 2020
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5A46
| FGFR1 in complex with dovitinib | 分子名称: | 1,2-ETHANEDIOL, 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... | 著者 | Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L. | 登録日 | 2015-06-05 | 公開日 | 2015-08-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase. Nat.Commun., 6, 2015
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8RHS
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1AAW
| THE STRUCTURAL BASIS FOR THE ALTERED SUBSTRATE SPECIFICITY OF THE R292D ACTIVE SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM E. COLI | 分子名称: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | 著者 | Almo, S.C, Smith, D.L, Danishefsky, A.T, Ringe, D. | 登録日 | 1993-07-13 | 公開日 | 1993-10-31 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli. Protein Eng., 7, 1994
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6BSY
| HIV-1 Rev assembly domain (residues 1-69) | 分子名称: | PHOSPHATE ION, Protein Rev | 著者 | Watts, N.R, Eren, E, Zhuang, X, Wang, Y.X, Steven, A.C, Wingfield, P.T. | 登録日 | 2017-12-04 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | A new HIV-1 Rev structure optimizes interaction with target RNA (RRE) for nuclear export. J. Struct. Biol., 203, 2018
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6G8Z
| Structure of the pore domain of homomeric mLRRC8A volume-regulated anion channel at 3.66 A resolution | 分子名称: | Volume-regulated anion channel subunit LRRC8A | 著者 | Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. | 登録日 | 2018-04-10 | 公開日 | 2018-05-16 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Structure of a volume-regulated anion channel of the LRRC8 family. Nature, 558, 2018
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6BMM
| Structure of human DHHC20 palmitoyltransferase, space group P21 | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,5S)-hexane-2,5-diol, PHOSPHATE ION, ... | 著者 | Rana, M.S, Lee, C.-J, Banerjee, A. | 登録日 | 2017-11-15 | 公開日 | 2018-01-24 | 最終更新日 | 2018-03-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Fatty acyl recognition and transfer by an integral membraneS-acyltransferase. Science, 359, 2018
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6BT9
| Chitinase ChiA74 from Bacillus thuringiensis | 分子名称: | CALCIUM ION, Chitinase | 著者 | Juarez-Hernandez, E, Brieba, L.G, Torres-Larios, A, Jimenez-Sandoval, P, Barboza-Corona, J. | 登録日 | 2017-12-05 | 公開日 | 2019-03-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | The crystal structure of the chitinase ChiA74 of Bacillus thuringiensis has a multidomain assembly. Sci Rep, 9, 2019
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5HEL
| Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2 | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 2 | 著者 | Tallant, C, Lori, C, Pasquo, A, Chiaraluce, R, Consalvi, V, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S. | 登録日 | 2016-01-06 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2 To Be Published
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1AI1
| HIV-1 V3 LOOP MIMIC | 分子名称: | AIB142, IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), IGG1-KAPPA 59.1 FAB (LIGHT CHAIN) | 著者 | Ghiara, J.B, Wilson, I.A. | 登録日 | 1996-11-06 | 公開日 | 1997-05-15 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site. J.Mol.Biol., 266, 1997
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5HG0
| Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis complex with SAM | 分子名称: | Pantothenate synthetase, S-ADENOSYLMETHIONINE | 著者 | Chang, C, Maltseva, N, Kim, Y, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-01-07 | 公開日 | 2016-01-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis complex with SAM To Be Published
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6HIE
| The ATAD2 bromodomain in complex with compound 17 | 分子名称: | (2~{R})-1-[2-[4,4-bis(fluoranyl)cyclohexyl]ethyl]-~{N}-(4-ethanoyl-1,3-thiazol-2-yl)piperazine-2-carboxamide, ATPase family AAA domain-containing protein 2, SULFATE ION | 著者 | Sledz, P, Caflisch, A. | 登録日 | 2018-08-29 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers. Acs Med.Chem.Lett., 11, 2020
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7L0C
| Ligand-free PTP1B T177G | 分子名称: | Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Shen, R.D, Hengge, A.C, Johnson, S.J. | 登録日 | 2020-12-11 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Single Residue on the WPD-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases. Jacs Au, 1, 2021
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5HGO
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5Z3S
| Crystal structure of butanol modified signaling protein from buffalo (SPB-40) at 1.65 A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-BUTANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Singh, P.K, Chaudhary, A, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2018-01-08 | 公開日 | 2018-02-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A glycoprotein from mammary gland secreted during involution promotes apoptosis: Structural and biological studies. Arch. Biochem. Biophys., 644, 2018
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7L0M
| Vanadate-bound YopH G352T | 分子名称: | Protein-tyrosine-phosphatase, VANADATE ION | 著者 | Shen, R.D, Hengge, A.C, Johnson, S.J. | 登録日 | 2020-12-11 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Single Residue on the WPD-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases. Jacs Au, 1, 2021
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