6BGS
| Caspase-3 Mutant - S150Y | 分子名称: | Ac-Asp-Glu-Val-Asp-CMK, Caspase-3 | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | 登録日 | 2017-10-29 | 公開日 | 2018-02-21 | 最終更新日 | 2018-04-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases. J. Biol. Chem., 293, 2018
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4YQJ
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6BHW
| B. subtilis SsbA | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Single-stranded DNA-binding protein A | 著者 | Dubiel, K.D, Myers, A.R, Satyshur, K.A, Keck, J.L. | 登録日 | 2017-10-31 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.208 Å) | 主引用文献 | Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins. J. Mol. Biol., 431, 2019
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6FAB
| THREE-DIMENSIONAL STRUCTURE OF MURINE ANTI-P-AZOPHENYLARSONATE FAB 36-71. 1. X-RAY CRYSTALLOGRAPHY, SITE-DIRECTED MUTAGENESIS, AND MODELING OF THE COMPLEX WITH HAPTEN | 分子名称: | IGG1-KAPPA 36-71 FAB (HEAVY CHAIN), IGG1-KAPPA 36-71 FAB (LIGHT CHAIN) | 著者 | Strong, R.K, Rose, D.R, Petsko, G.A, Sharon, J, Margolies, M.N. | 登録日 | 1991-01-17 | 公開日 | 1993-01-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten. Biochemistry, 30, 1991
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6MF6
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8FAY
| Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G) | 分子名称: | Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*CP*AP*(NR1)P*GP*TP*CP*T)-3'), ... | 著者 | Trasvina-Arenas, C.H, Lin, W.J, Demir, M, Fisher, A.J, David, S.S, Horvath, M.P. | 登録日 | 2022-11-29 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G) To Be Published
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4YS0
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4RV7
| Characterization of an essential diadenylate cyclase | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Diadenylate cyclase, HEXANE-1,6-DIOL, ... | 著者 | Dickmanns, A, Neumann, P, Ficner, R. | 登録日 | 2014-11-25 | 公開日 | 2015-01-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and Biochemical Analysis of the Essential Diadenylate Cyclase CdaA from Listeria monocytogenes. J.Biol.Chem., 290, 2015
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4YHA
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5HWB
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6FNT
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8U53
| Mechanically activated ion channel OSCA3.1 in nanodiscs | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CSC1-like protein ERD4, PALMITIC ACID, ... | 著者 | Jojoa-Cruz, S, Lee, W.H, Ward, A.B. | 登録日 | 2023-09-12 | 公開日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli. Elife, 12, 2024
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8RT3
| Hen Egg White Lysozyme Crystallized with Bioassembler in Space Microgravity Conditions | 分子名称: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, CHLORIDE ION, GADOLINIUM ATOM, ... | 著者 | MacCarthy, C, Koudan, E.V, Petrov, S.V, Levin, A.A, Khesuani, Y.D, Borshchevskiy, V. | 登録日 | 2024-01-25 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Hen Egg White Lysozyme Crystallized with Bioassembler in Space Microgravity Conditions To Be Published
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6FOI
| Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Wright, G.S.A, Sala, F.A, Antonyuk, S.V, Garratt, R.C, Hasnain, S.S. | 登録日 | 2018-02-07 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS. Plos Biol., 17, 2019
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6LYM
| Crystal structure of D657A mutant of formylglycinamidine synthetase | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Sharma, N, Tanwar, A.S, Anand, R. | 登録日 | 2020-02-14 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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4YJX
| The structure of Agrobacterium tumefaciens ClpS2 bound to L-phenylalaninamide | 分子名称: | ATP-dependent Clp protease adapter protein ClpS 2, PHENYLALANINE AMIDE, SULFATE ION | 著者 | Stein, B, Grant, R.A, Sauer, R.T, Baker, T.A. | 登録日 | 2015-03-03 | 公開日 | 2016-01-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.547 Å) | 主引用文献 | Structural Basis of an N-Degron Adaptor with More Stringent Specificity. Structure, 24, 2016
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7JUQ
| Crystal Structure of KSR2:MEK1 in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 2, ... | 著者 | Khan, Z.M, Dar, A.C. | 登録日 | 2020-08-20 | 公開日 | 2020-09-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Structural basis for the action of the drug trametinib at KSR-bound MEK. Nature, 588, 2020
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6BOQ
| Human APE1 substrate complex with an A/A mismatch adjacent the THF | 分子名称: | 1,2-ETHANEDIOL, 21-mer DNA, DNA-(apurinic or apyrimidinic site) lyase | 著者 | Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. | 登録日 | 2017-11-20 | 公開日 | 2018-08-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018
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7JUR
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7JUX
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7XZR
| Crystal structure of TNIK-AMPPNP-thiopeptide TP15 complex | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... | 著者 | Hamada, K, Vinogradov, A.A, Zhang, Y, Chang, J.S, Nishimura, H, Goto, Y, Onaka, H, Suga, H, Ogata, K, Sengoku, T. | 登録日 | 2022-06-03 | 公開日 | 2022-10-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors. J.Am.Chem.Soc., 144, 2022
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5JCA
| NADP(H) bound NADH-dependent Ferredoxin:NADP Oxidoreductase (NfnI) from Pyrococcus furiosus | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Zadvornyy, O.A, Schut, G.J, Nguyen, D.M, Artz, J.H, Tokmina-Lukaszewska, M, Lipscomb, G, Adams, M.W, Peters, J.W. | 登録日 | 2016-04-14 | 公開日 | 2017-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Mechanistic insights into energy conservation by flavin-based electron bifurcation. Nat. Chem. Biol., 13, 2017
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5D2H
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5D2R
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5UZ3
| Solution Structure of a DNA Dodecamer with 5-methylcytosine at the 9th position and 8-oxoguanine at the 10th position | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(DMC)P*(8OG)P*CP*G)-3') | 著者 | Gruber, D.R, Hoppins, J.J, Miears, H.L, Endutkin, A.V, Zharkov, D.O, Smirnov, S.L. | 登録日 | 2017-02-24 | 公開日 | 2017-05-31 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation. Nucleic Acids Res., 46, 2018
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