6FNT

Ergothioneine-biosynthetic methyltransferase EgtD in complex with pyrrolidinohistidine

Summary for 6FNT

Entry DOI	10.2210/pdb6fnt/pdb
Descriptor	Histidine N-alpha-methyltransferase, Pyrrolidinohistidine (3 entities in total)
Functional Keywords	ergothioneine, methyltransferase, inhibitor complex, transferase
Biological source	Mycobacterium smegmatis
Total number of polymer chains	2
Total formula weight	70987.91
Authors	Vit, A.,Blankenfeldt, W.,Seebeck, F.P. (deposition date: 2018-02-05, release date: 2018-06-13, Last modification date: 2024-01-17)
Primary citation	Misson, L.,Burn, R.,Vit, A.,Hildesheim, J.,Beliaeva, M.A.,Blankenfeldt, W.,Seebeck, F.P. Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD. ACS Chem. Biol., 13:1333-1342, 2018 Cited by PubMed: 29658702 DOI: 10.1021/acschembio.8b00127 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation