6MF6

Crystal structure of budding yeast Cdc5 polo-box domain in complex with the Dbf4 polo-interacting region.

Summary for 6MF6

Entry DOI	10.2210/pdb6mf6/pdb
Descriptor	Cell cycle serine/threonine-protein kinase CDC5/MSD2, DDK kinase regulatory subunit DBF4 (2 entities in total)
Functional Keywords	mitosis, dbf4, polo-like kinases, cell cycle, transferase
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Total number of polymer chains	4
Total formula weight	71419.47
Authors	Guarne, A.,Almawi, A.W. (deposition date: 2018-09-09, release date: 2020-02-19, Last modification date: 2023-10-11)
Primary citation	Almawi, A.W.,Langlois-Lemay, L.,Boulton, S.,Rodriguez Gonzalez, J.,Melacini, G.,D'Amours, D.,Guarne, A. Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division. Sci Rep, 10:3379-3379, 2020 Cited by PubMed: 32099015 DOI: 10.1038/s41598-020-60344-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation