1T0V
 
 | | NMR Solution Structure of the Engineered Lipocalin FluA(R95K) Northeast Structural Genomics Target OR17 | | 分子名称: | BILIN-BINDING PROTEIN | | 著者 | Mills, J.L, Liu, G, Skerra, A, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2004-04-13 | | 公開日 | 2005-06-14 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure and dynamics of the engineered fluorescein-binding lipocalin FluA reveal rigidification of beta-barrel and variable loops upon enthalpy-driven ligand binding.
Biochemistry, 48, 2009
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5HF4
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4RCT
 | | Crystal structure of R-protein of NgoAVII restriction endonuclease | | 分子名称: | Restriction endonuclease R.NgoVII | | 著者 | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | | 登録日 | 2014-09-17 | | 公開日 | 2014-12-24 | | 最終更新日 | 2014-12-31 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.
Nucleic Acids Res., 42, 2014
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4YPC
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1RFS
 | | RIESKE SOLUBLE FRAGMENT FROM SPINACH | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, RIESKE PROTEIN | | 著者 | Carrell, C.J, Zhang, H, Cramer, W.A, Smith, J.L. | | 登録日 | 1997-08-14 | | 公開日 | 1998-01-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Biological identity and diversity in photosynthesis and respiration: structure of the lumen-side domain of the chloroplast Rieske protein.
Structure, 5, 1997
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1KKO
 | | CRYSTAL STRUCTURE OF CITROBACTER AMALONATICUS METHYLASPARTATE AMMONIA LYASE | | 分子名称: | 3-METHYLASPARTATE AMMONIA-LYASE, SULFATE ION | | 著者 | Levy, C.W, Buckley, P.A, Sedelnikova, S, Kato, Y, Asano, Y, Rice, D.W, Baker, P.J. | | 登録日 | 2001-12-10 | | 公開日 | 2002-01-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Insights into enzyme evolution revealed by the structure of methylaspartate ammonia lyase.
Structure, 10, 2002
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6VRM
 | | T cell receptor-p53-HLA-A2 complex | | 分子名称: | Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ... | | 著者 | Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A. | | 登録日 | 2020-02-08 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
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4A5V
 | | Solution structure ensemble of the two N-terminal apple domains (residues 58-231) of Toxoplasma gondii microneme protein 4 | | 分子名称: | MICRONEMAL PROTEIN 4 | | 著者 | Marchant, J, Cowper, B, Liu, Y, Lai, L, Pinzan, C, Marq, J.B, Friedrich, N, Sawmynaden, K, Chai, W, Childs, R.A, Saouros, S, Simpson, P, Barreira, M.C.R, Feizi, T, Soldati-Favre, D, Matthews, S. | | 登録日 | 2011-10-28 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Galactose Recognition by the Apicomplexan Parasite Toxoplasma Gondii.
J.Biol.Chem., 287, 2012
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6IYK
 | | The structure of EntE with 2-nitrobenzoyl adenylate analog | | 分子名称: | 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex, 5'-O-[(2-nitrobenzene-1-carbonyl)sulfamoyl]adenosine | | 著者 | Miyanaga, A, Ishikawa, F. | | 登録日 | 2018-12-17 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | An Engineered Aryl Acid Adenylation Domain with an Enlarged Substrate Binding Pocket.
Angew.Chem.Int.Ed.Engl., 58, 2019
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3PRF
 | | Crystal Structure of Human B-Raf Kinase Domain in Complex with a Non-Oxime Furopyridine Inhibitor | | 分子名称: | 2-chloro-5-{[2-(pyrimidin-2-yl)furo[2,3-c]pyridin-3-yl]amino}phenol, Serine/threonine-protein kinase B-raf | | 著者 | Voegtli, W.C, Vigers, G.P.A, Morales, T, Brandhuber, B.J. | | 登録日 | 2010-11-29 | | 公開日 | 2011-02-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Non-oxime inhibitors of B-Raf(V600E) kinase.
Bioorg.Med.Chem.Lett., 21, 2011
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3QGZ
 | | Re-investigated high resolution crystal structure of histidine triad nucleotide-binding protein 1 (HINT1) from rabbit complexed with adenosine | | 分子名称: | ADENOSINE, Histidine triad nucleotide-binding protein 1 | | 著者 | Dolot, R.M, Ozga, M, Krakowiak, A, Nawrot, B, Stec, W.J. | | 登録日 | 2011-01-25 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | High-resolution X-ray crystal structure of rabbit histidine triad nucleotide-binding protein 1 (rHINT1) - adenosine complex at 1.10A resolution
Acta Crystallogr.,Sect.D, 67, 2011
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5TQS
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4RY0
 | | Crystal structure of ribose transporter solute binding protein RHE_PF00037 from Rhizobium etli CFN 42, TARGET EFI-511357, in complex with D-ribose | | 分子名称: | CALCIUM ION, CHLORIDE ION, Probable ribose ABC transporter, ... | | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Al Obaidi, N, Morisco, L.L, Wasserman, S.R, Chamala, S, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Lafleur, J, Hillerich, B, Siedel, R.D, Love, J, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2014-12-12 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal Structure of Ribose Transporter Solute Binding Protein from Rhizobium Etly, Target Efi-511357
To be Published
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4D0O
 | | AKAP13 (AKAP-Lbc) DH domain | | 分子名称: | A-KINASE ANCHOR PROTEIN 13 | | 著者 | Abdul Azeez, K.R, Shrestha, L, Krojer, T, Allerston, C, von Delft, F, Bountra, C, Arrowsmith, C, Edwards, A.M, Knapp, S, Klussmann, E, Elkins, J.M. | | 登録日 | 2014-04-29 | | 公開日 | 2014-05-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | The Crystal Structure of the Rhoa : Akap-Lbc Dh-Ph Domain Complex.
Biochem.J., 464, 2014
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7XFX
 | | Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.28 A resolution. | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Maurya, A, Singh, P.K, Viswanathan, V, Sharma, P, Sharma, S, Singh, T.P. | | 登録日 | 2022-04-02 | | 公開日 | 2022-05-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.28 A resolution.
To Be Published
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1TIY
 | | X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160 | | 分子名称: | Guanine deaminase, ZINC ION | | 著者 | Kuzin, A.P, Vorobiev, S, Edstrom, W, Forouhar, F, Acton, T, Shastry, R, Ma, L.-C, Chiang, Y.-W, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2004-06-02 | | 公開日 | 2004-06-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS
NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160
To be published
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7XFY
 | | Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.67 A resolution. | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Maurya, A, Singh, P.K, Viswanathan, V, Sharma, P, Sharma, S, Singh, T.P. | | 登録日 | 2022-04-02 | | 公開日 | 2022-05-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.67 A resolution.
To Be Published
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6W8Q
 | | Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments | | 分子名称: | 2-oxo-1,2,5,6,7,8-hexahydroquinazoline-4-carboxylic acid, Nonstructural polyprotein | | 著者 | Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. | | 登録日 | 2020-03-21 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design.
Plos One, 16, 2021
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5HRY
 | | Computationally Designed Cyclic Dimer ank3C2_1 | | 分子名称: | ank3C2_1 | | 著者 | Cascio, D, McNamara, D.E, Fallas, J.A, Baker, D, Yeates, T.O. | | 登録日 | 2016-01-24 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
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7XNZ
 | | Native cystathionine beta-synthase of Mycobacterium tuberculosis. | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Putative cystathionine beta-synthase Rv1077 | | 著者 | Bandyopadhyay, P, Pramanick, I, Biswas, R, Sabarinath, P.S, Sreedharan, S, Singh, S, Rajmani, R, Laxman, S, Dutta, S, Singh, A. | | 登録日 | 2022-04-30 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | S-Adenosylmethionine-responsive cystathionine beta-synthase modulates sulfur metabolism and redox balance in Mycobacterium tuberculosis.
Sci Adv, 8, 2022
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5W3Q
 | | L28F E.coli DHFR in complex with NADPH | | 分子名称: | CALCIUM ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Oyen, D, Wright, P.E, Wilson, I.A. | | 登録日 | 2017-06-08 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | | 主引用文献 | Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion.
J. Am. Chem. Soc., 139, 2017
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7XOH
 | | Cystathionine beta-synthase of Mycobacterium tuberculosis in the presence of S-adenosylmethionine. | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Putative cystathionine beta-synthase Rv1077 | | 著者 | Bandyopadhyay, P, Pramanick, I, Biswas, R, Sabarinath, P.S, Sreedharan, S, Singh, S, Rajmani, R, Laxman, S, Dutta, S, Singh, A. | | 登録日 | 2022-05-01 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | S-Adenosylmethionine-responsive cystathionine beta-synthase modulates sulfur metabolism and redox balance in Mycobacterium tuberculosis.
Sci Adv, 8, 2022
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7XOY
 | | Cystathionine beta-synthase of Mycobacterium tuberculosis in the presence of S-adenosylmethionine and serine. | | 分子名称: | Putative cystathionine beta-synthase Rv1077, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | | 著者 | Bandyopadhyay, P, Pramanick, I, Biswas, R, Sabarinath, P.S, Sreedharan, S, Singh, S, Rajmani, R, Laxman, S, Dutta, S, Singh, A. | | 登録日 | 2022-05-01 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | | 主引用文献 | S-Adenosylmethionine-responsive cystathionine beta-synthase modulates sulfur metabolism and redox balance in Mycobacterium tuberculosis.
Sci Adv, 8, 2022
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5NW2
 | | pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-3,3-dimethyl-2-(oxetane-3-carboxamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 19) | | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-3,3-dimethyl-2-(oxetan-3-ylcarbonylamino)butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | 著者 | Gadd, M.S, Soares, P, Ciulli, A. | | 登録日 | 2017-05-04 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298).
J. Med. Chem., 61, 2018
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1RBY
 | | Human GAR Tfase complex structure with 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid and substrate beta-GAR | | 分子名称: | GLYCINAMIDE RIBONUCLEOTIDE, N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID, PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | | 著者 | Zhang, Y, Desharnais, J, Boger, D.L, Wilson, I.A. | | 登録日 | 2003-11-03 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Human GAR Tfase complex structure
To be Published
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