7XOH

Cystathionine beta-synthase of Mycobacterium tuberculosis in the presence of S-adenosylmethionine.

Summary for 7XOH

Entry DOI	10.2210/pdb7xoh/pdb
EMDB information	33348
Descriptor	Putative cystathionine beta-synthase Rv1077, PYRIDOXAL-5'-PHOSPHATE (2 entities in total)
Functional Keywords	cystathionine beta-synthase, transsulfuration, s-adenosylmethionine, lyase
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	4
Total formula weight	202127.96
Authors	Bandyopadhyay, P.,Pramanick, I.,Biswas, R.,Sabarinath, P.S.,Sreedharan, S.,Singh, S.,Rajmani, R.,Laxman, S.,Dutta, S.,Singh, A. (deposition date: 2022-05-01, release date: 2022-05-25, Last modification date: 2022-12-07)
Primary citation	Bandyopadhyay, P.,Pramanick, I.,Biswas, R.,Ps, S.,Sreedharan, S.,Singh, S.,Rajmani, R.S.,Laxman, S.,Dutta, S.,Singh, A. S-Adenosylmethionine-responsive cystathionine beta-synthase modulates sulfur metabolism and redox balance in Mycobacterium tuberculosis. Sci Adv, 8:eabo0097-eabo0097, 2022 Cited by PubMed: 35749503 DOI: 10.1126/sciadv.abo0097 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation