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7XOH

Cystathionine beta-synthase of Mycobacterium tuberculosis in the presence of S-adenosylmethionine.

Functional Information from GO Data
ChainGOidnamespacecontents
A0004122molecular_functioncystathionine beta-synthase activity
A0004124molecular_functioncysteine synthase activity
A0005576cellular_componentextracellular region
A0005737cellular_componentcytoplasm
A0005886cellular_componentplasma membrane
A0006534biological_processcysteine metabolic process
A0006535biological_processcysteine biosynthetic process from serine
A0009069biological_processserine family amino acid metabolic process
A0009274cellular_componentpeptidoglycan-based cell wall
A0016829molecular_functionlyase activity
A0019343biological_processcysteine biosynthetic process via cystathionine
A0030170molecular_functionpyridoxal phosphate binding
A0044272biological_processsulfur compound biosynthetic process
B0004122molecular_functioncystathionine beta-synthase activity
B0004124molecular_functioncysteine synthase activity
B0005576cellular_componentextracellular region
B0005737cellular_componentcytoplasm
B0005886cellular_componentplasma membrane
B0006534biological_processcysteine metabolic process
B0006535biological_processcysteine biosynthetic process from serine
B0009069biological_processserine family amino acid metabolic process
B0009274cellular_componentpeptidoglycan-based cell wall
B0016829molecular_functionlyase activity
B0019343biological_processcysteine biosynthetic process via cystathionine
B0030170molecular_functionpyridoxal phosphate binding
B0044272biological_processsulfur compound biosynthetic process
C0004122molecular_functioncystathionine beta-synthase activity
C0004124molecular_functioncysteine synthase activity
C0005576cellular_componentextracellular region
C0005737cellular_componentcytoplasm
C0005886cellular_componentplasma membrane
C0006534biological_processcysteine metabolic process
C0006535biological_processcysteine biosynthetic process from serine
C0009069biological_processserine family amino acid metabolic process
C0009274cellular_componentpeptidoglycan-based cell wall
C0016829molecular_functionlyase activity
C0019343biological_processcysteine biosynthetic process via cystathionine
C0030170molecular_functionpyridoxal phosphate binding
C0044272biological_processsulfur compound biosynthetic process
D0004122molecular_functioncystathionine beta-synthase activity
D0004124molecular_functioncysteine synthase activity
D0005576cellular_componentextracellular region
D0005737cellular_componentcytoplasm
D0005886cellular_componentplasma membrane
D0006534biological_processcysteine metabolic process
D0006535biological_processcysteine biosynthetic process from serine
D0009069biological_processserine family amino acid metabolic process
D0009274cellular_componentpeptidoglycan-based cell wall
D0016829molecular_functionlyase activity
D0019343biological_processcysteine biosynthetic process via cystathionine
D0030170molecular_functionpyridoxal phosphate binding
D0044272biological_processsulfur compound biosynthetic process
Functional Information from PROSITE/UniProt
site_idPS00216
Number of Residues16
DetailsSUGAR_TRANSPORT_1 Sugar transport proteins signature 1. LGFLSEGAGRRklaa..A
ChainResidueDetails
BLEU454-ALA469

site_idPS00217
Number of Residues26
DetailsSUGAR_TRANSPORT_2 Sugar transport proteins signature 2. VaGIGtGGtitgagrYlkEvsggrvR
ChainResidueDetails
BVAL177-ARG202

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
BASN74
BSER269
AASN74
ASER269
CASN74
CSER269
DASN74
DSER269

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000250
ChainResidueDetails
BLYS44
ALYS44
CLYS44
DLYS44

site_idSWS_FT_FI3
Number of Residues8
DetailsCROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup) => ECO:0000269|PubMed:20066036
ChainResidueDetails
BLYS428
ALYS428
CLYS428
DLYS428

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PDB entries from 2024-11-06

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