6FCP
| Crystal structure of 14-3-3 sigma in complex with Shroom3 P1244L | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Leysen, S, Meijer, F.A, Milroy, L.G, Ottmann, C. | 登録日 | 2017-12-20 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Characterization of Coding/Noncoding Variants forSHROOM3in Patients with CKD. J. Am. Soc. Nephrol., 29, 2018
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8RAS
| Plastid-encoded RNA polymerase transcription elongation complex | 分子名称: | DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Webster, M.W, Pramanick, I, Vergara-Cruces, A. | 登録日 | 2023-12-01 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | 主引用文献 | Structure of the plant plastid-encoded RNA polymerase. Cell, 187, 2024
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4S0R
| Structure of GS-TnrA complex | 分子名称: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... | 著者 | Schumacher, M.A, Chinnam, N.G, Cuthbert, B, Tonthat, N.K. | 登録日 | 2015-01-04 | 公開日 | 2015-03-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis. Genes Dev., 29, 2015
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7PVK
| X-ray structure of dimeric PorX (T272A mutant), in complex with pGpG. | 分子名称: | BERYLLIUM TRIFLUORIDE ION, FORMIC ACID, GLYCEROL, ... | 著者 | Schmitz, C.A, Madej, M, Potempa, J, Sola, M. | 登録日 | 2021-10-04 | 公開日 | 2022-12-14 | 最終更新日 | 2023-01-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Response regulator PorX coordinates oligonucleotide signalling and gene expression to control the secretion of virulence factors Nucleic Acids Res., 50, 2022
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6VNA
| Pden_1323 | 分子名称: | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding protein | 著者 | Isiorho, E.A, Mansoorabadi, S.O. | 登録日 | 2020-01-29 | 公開日 | 2021-02-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A noncanonical heme oxygenase specific for the degradation of c-type heme. J.Biol.Chem., 296, 2021
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8DLN
| Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization. Nat Commun, 13, 2022
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8V5R
| Active conformation of DNA polymerase gamma bound to DNA | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, ... | 著者 | Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C. | 登録日 | 2023-11-30 | 公開日 | 2024-07-10 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis. Nucleic Acids Res., 52, 2024
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6BF7
| Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain | 分子名称: | Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-10-26 | 公開日 | 2018-02-07 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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8DLK
| Cryo-EM structure of SARS-CoV-2 Alpha (B.1.1.7) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization. Nat Commun, 13, 2022
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7MJK
| Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (class 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab ab1 Heavy Chain, ... | 著者 | Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S. | 登録日 | 2021-04-20 | 公開日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies. Plos Biol., 19, 2021
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8DLR
| Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with Fab 4-8 (focused refinement of NTD and 4-8) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4-8 heavy chain, Fab 4-8 light chain, ... | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization. Nat Commun, 13, 2022
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8DLS
| Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4A8 heavy chain, ... | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization. Nat Commun, 13, 2022
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4S3B
| IspG in complex with Intermediate II | 分子名称: | (3S)-1,3-dihydroxy-4-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}-2-methylbut-2-ylium, carbokation intermediate, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, ... | 著者 | Quitterer, F, Frank, A, Wang, K, Rao, G, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | 登録日 | 2015-01-26 | 公開日 | 2015-04-29 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427, 2015
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5FXU
| Crystal Structure of Puumala virus Gn glycoprotein ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE POLYPROTEIN, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, S, Rissanen, I, Zeltina, A, Hepojoki, J, Raghwani, J, Harlos, K, Pybus, O.G, Huiskonen, J.T, Bowden, T.A. | 登録日 | 2016-03-02 | 公開日 | 2016-05-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | A Molecular-Level Account of the Antigenic Hantaviral Surface. Cell Rep., 15, 2016
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7UTH
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7MJG
| Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S. | 登録日 | 2021-04-20 | 公開日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies. Plos Biol., 19, 2021
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8DLV
| Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization. Nat Commun, 13, 2022
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7KH2
| Structure of N-citrylornithine decarboxylase bound with PLP | 分子名称: | GLYCEROL, N-citrylornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Deng, X, Tomchick, D, Phillips, M, Michael, A. | 登録日 | 2020-10-19 | 公開日 | 2020-12-16 | 最終更新日 | 2021-07-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Alternative pathways utilize or circumvent putrescine for biosynthesis of putrescine-containing rhizoferrin. J.Biol.Chem., 296, 2020
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7PWJ
| dUTPase from human in complex with Stl | 分子名称: | 1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, ... | 著者 | Sanz-Frasquet, C, Marina, A. | 登録日 | 2021-10-06 | 公開日 | 2022-12-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.944 Å) | 主引用文献 | The Bacteriophage-Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases. Microbiol Spectr, 11, 2023
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7MHP
| Ensemble refinement structure of SARS-CoV-2 main protease (Mpro) at 298 K at high humidity | 分子名称: | 3C-like proteinase, ZINC ION | 著者 | Ebrahim, A, Riley, B.T, Kumaran, D, Andi, B, Fuchs, M.R, McSweeney, S, Keedy, D.A. | 登録日 | 2021-04-15 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.0005 Å) | 主引用文献 | The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ) Iucrj, 9, 2022
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7PWX
| dUTPase from M. tuberculosis in complex with Stl | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Marina, A, Sanz-Frasquet, C. | 登録日 | 2021-10-07 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | The Bacteriophage-Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases. Microbiol Spectr, 11, 2023
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7MJM
| Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S. | 登録日 | 2021-04-20 | 公開日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies. Plos Biol., 19, 2021
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4TKN
| Structure of the SNX17 FERM domain bound to the second NPxF motif of KRIT1 | 分子名称: | Krev interaction trapped protein 1, Sorting nexin-17 | 著者 | Stiegler, A.L, Zhang, R, Liu, W, Boggon, T.J. | 登録日 | 2014-05-27 | 公開日 | 2014-07-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1). J.Biol.Chem., 289, 2014
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5FBU
| Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin-phosphate | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphoenolpyruvate synthase, ... | 著者 | Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-12-14 | 公開日 | 2015-12-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Rifampin phosphotransferase is an unusual antibiotic resistance kinase. Nat Commun, 7, 2016
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6B7B
| Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 5-methoxy-2-methyl-1H-indole | 分子名称: | 5-methoxy-2-methyl-1H-indole, DIMETHYL SULFOXIDE, PYROPHOSPHATE 2-, ... | 著者 | Proudfoot, A.W, Bussiere, D, Lingel, A. | 登録日 | 2017-10-03 | 公開日 | 2017-12-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | 主引用文献 | High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
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