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3KY7
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BU of 3ky7 by Molmil
2.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA252
Descriptor: tRNA (guanine-N(1)-)-methyltransferase
Authors:Halavaty, A.S, Minasov, G, Winsor, J, Dubrovska, I, Shuvalova, L, See, R, Zoraghi, R, Reiner, N, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-12-04
Release date:2009-12-22
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA252
To be Published
2H40
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BU of 2h40 by Molmil
Crystal structure of the catalytic domain of unliganded PDE5
Descriptor: MAGNESIUM ION, ZINC ION, cGMP-specific 3',5'-cyclic phosphodiesterase
Authors:Wang, H, Liu, Y, Huai, Q, Cai, J, Zoraghi, R, Francis, S.H, Corbin, J.D, Robinson, H, Xin, Z, Lin, G, Ke, H.
Deposit date:2006-05-23
Release date:2006-06-06
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
3T07
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BU of 3t07 by Molmil
Crystal structure of S. aureus Pyruvate Kinase in complex with a naturally occurring bis-indole alkaloid
Descriptor: (3S,5R)-3,5-bis(6-bromo-1H-indol-3-yl)piperazin-2-one, PHOSPHATE ION, Pyruvate kinase
Authors:Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
Deposit date:2011-07-19
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
3T05
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BU of 3t05 by Molmil
Crystal structure of S. aureus Pyruvate Kinase
Descriptor: PHOSPHATE ION, Pyruvate kinase
Authors:Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
Deposit date:2011-07-19
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
3T0T
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BU of 3t0t by Molmil
Crystal structure of S. aureus Pyruvate Kinase
Descriptor: N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide, PHOSPHATE ION, Pyruvate kinase
Authors:Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
Deposit date:2011-07-20
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase.
Acs Chem.Biol., 7, 2012
2H44
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BU of 2h44 by Molmil
Crystal structure of PDE5A1 in complex with icarisid II
Descriptor: 5,7-DIHYDROXY-2-(4-METHOXYPHENYL)-8-(3-METHYLBUTYL)-4-OXO-4H-CHROMEN-3-YL 6-DEOXY-ALPHA-L-MANNOPYRANOSIDE, MAGNESIUM ION, ZINC ION, ...
Authors:Wang, H, Ke, H.
Deposit date:2006-05-23
Release date:2006-06-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
2H42
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BU of 2h42 by Molmil
Crystal structure of PDE5 in complex with sildenafil
Descriptor: 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, ZINC ION, ...
Authors:Wang, H, Ke, H.
Deposit date:2006-05-23
Release date:2006-06-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006

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