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2GTJ
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BU of 2gtj by Molmil
Reduced form of ADAP hSH3-N-domain
分子名称: FYN-binding protein
著者Zimmermann, J, Kuehne, R, Freund, C.
登録日2006-04-28
公開日2007-06-05
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Redox-Regulated Conformational Changes in an SH3 Domain
Biochemistry, 46, 2007
2GTO
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BU of 2gto by Molmil
Oxidized form of ADAP hSH3-N
分子名称: FYN-binding protein
著者Freund, C, Zimmermann, J, Kuehne, R.
登録日2006-04-28
公開日2007-06-05
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Redox-Regulated Conformational Changes in an SH3 Domain
Biochemistry, 46, 2007
2JP2
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BU of 2jp2 by Molmil
Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2)
分子名称: Sprouty-related, EVH1 domain-containing protein 2
著者Fossi, M, Zimmermann, J, Jarchau, T, Lemak, A, Walter, U, Wiegelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC)
登録日2007-04-18
公開日2007-05-15
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献1H, 13C and 15N resonance assignment of the human Spred2 EVH1 domain
J.Biomol.NMR, 29, 2004
4NJ9
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BU of 4nj9 by Molmil
Crystal structure of Fab 8B10 in complex with MPTS
分子名称: 8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ...
著者Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日2013-11-08
公開日2014-11-12
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
4NJA
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BU of 4nja by Molmil
Crystal structure of Fab 6C8 in complex with MPTS
分子名称: 6C8 heavy chain, 6C8 light chain, 8-methoxypyrene-1,3,6-trisulfonic acid, ...
著者Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日2013-11-08
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
3ONL
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BU of 3onl by Molmil
yeast Ent3_ENTH-Vti1p_Habc complex structure
分子名称: Epsin-3, t-SNARE VTI1
著者Wang, J, Fang, P, Niu, L, Teng, M.
登録日2010-08-29
公開日2011-07-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
3ONK
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BU of 3onk by Molmil
yeast Ent3_ENTH domain
分子名称: Epsin-3
著者Wang, J, Fang, P, Niu, L, Teng, M.
登録日2010-08-29
公開日2011-07-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
3ONJ
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BU of 3onj by Molmil
Crystal structure of yeast Vti1p_Habc domain
分子名称: t-SNARE VTI1
著者Wang, J, Fang, P, Niu, L, Teng, M.
登録日2010-08-29
公開日2011-07-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
6M87
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BU of 6m87 by Molmil
Fab 10A6 in complex with MPTS
分子名称: 8-methoxypyrene-1,3,6-trisulfonic acid, Fab 10A6 heavy chain, Fab 10A6 light chain, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2018-08-21
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.609 Å)
主引用文献Structure and Dynamics of Stacking Interactions in an Antibody Binding Site.
Biochemistry, 58, 2019
5DGN
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BU of 5dgn by Molmil
Crystal structure of human FPPS in complex with compound 13
分子名称: 8-(naphthalen-1-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-08-28
公開日2015-09-30
最終更新日2015-11-04
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DIQ
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BU of 5diq by Molmil
Crystal structure of human FPPS in complex with salicylic acid derivative 3a
分子名称: 2-(naphthalen-1-ylmethoxy)benzoic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-01
公開日2015-09-30
最終更新日2016-07-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DJP
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BU of 5djp by Molmil
Crystal structure of human FPPS in complex with biaryl compound 5
分子名称: 4-(naphthalen-1-yl)-1H-indole-2-carboxylic acid, Farnesyl pyrophosphate synthase, PHOSPHATE ION
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-09-30
最終更新日2015-11-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DJV
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BU of 5djv by Molmil
Crystal structure of human FPPS in complex with biaryl compound 8e
分子名称: 8-(naphthalen-1-yl)-6-(1H-pyrrol-2-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-10-07
最終更新日2015-11-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DJR
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BU of 5djr by Molmil
Crystal structure of human FPPS in complex with biaryl compound 6
分子名称: 1H,1'H-4,4'-biindole-2-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-09-30
最終更新日2015-11-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DGS
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BU of 5dgs by Molmil
Crystal structure of human FPPS in complex with the monophosphonate compound 15
分子名称: Farnesyl pyrophosphate synthase, {(E)-2-[6-(acetylamino)-8-(naphthalen-1-yl)quinolin-2-yl]ethenyl}phosphonic acid
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-08-28
公開日2016-07-13
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献A General Strategy for Targeting Drugs to Bone.
Angew.Chem.Int.Ed.Engl., 54, 2015
5DGM
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BU of 5dgm by Molmil
Crystal structure of human FPPS in complex with monophosphonate compound 7
分子名称: Farnesyl pyrophosphate synthase, PHOSPHATE ION, {2-[(phosphonomethyl)carbamoyl]-1H-benzo[g]indol-1-yl}acetic acid
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-08-28
公開日2016-07-13
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献A General Strategy for Targeting Drugs to Bone.
Angew.Chem.Int.Ed.Engl., 54, 2015

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