5Y2F
| Human SIRT6 in complex with allosteric activator MDL-801 | 分子名称: | 5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid, 9-mer peptide QTARKSTGG, DI(HYDROXYETHYL)ETHER, ... | 著者 | Zhang, J, Huang, Z, Song, K. | 登録日 | 2017-07-25 | 公開日 | 2018-11-07 | 最終更新日 | 2018-11-28 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Identification of a cellularly active SIRT6 allosteric activator. Nat. Chem. Biol., 14, 2018
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8ONH
| Variant Surface Glycoprotein VSG11wt-Oil | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein, alpha-D-glucopyranose, ... | 著者 | Zeelen, J.P, Stebbins, C.E, Foti, K, Gkeka, A, Vlachou, E.P. | 登録日 | 2023-04-03 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
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8OK4
| Variant Surface Glycoprotein VSG11wt-Oil | 分子名称: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F, Foti, K. | 登録日 | 2023-03-27 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
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8OK8
| Variant Surface Glycoprotein VSG615 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 615, ... | 著者 | Zeelen, J.P, Stebbins, C.E, Chandra, M. | 登録日 | 2023-03-27 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
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8OK5
| Variant Surface Glycoprotein VSG11 monomer with iodine | 分子名称: | IODIDE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ... | 著者 | Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F. | 登録日 | 2023-03-27 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
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8OK6
| Variant Surface Glycoprotein VSG11 two monomers | 分子名称: | SULFATE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ... | 著者 | Gkeka, A, Vlachou, E.P, Zeelen, J.P, Stebbins, C.E. | 登録日 | 2023-03-27 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
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8Q0P
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8Q0E
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1LYP
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6L6Z
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6LFG
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6BI6
| Solution NMR structure of uncharacterized protein YejG | 分子名称: | Uncharacterized protein YejG | 著者 | Mohanty, B, Finn, T.J, Macindoe, I, Zhong, J, Patrick, W.M, Mackay, J.P. | 登録日 | 2017-11-01 | 公開日 | 2018-11-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The uncharacterized bacterial protein YejG has the same architecture as domain III of elongation factor G. Proteins, 87, 2019
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7YK1
| Structural basis of human PRPS2 filaments | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Lu, G.M, Hu, H.H, Liu, J.L. | 登録日 | 2022-07-21 | 公開日 | 2023-08-02 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis of human PRPS2 filaments. Cell Biosci, 13, 2023
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7X4B
| Crystal Structure of An Anti-CRISPR Protein | 分子名称: | Anti-CRISPR protein (AcrIIC1), SULFATE ION | 著者 | Hu, J, Zhang, S, Gao, J.Y, Liu, X, Liu, J. | 登録日 | 2022-03-02 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1. Nat Commun, 13, 2022
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8IAM
| Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3D) complex | 分子名称: | Chimera of Long chain base biosynthesis protein 1 and Serine palmitoyltransferase 1, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Xie, T, Gong, X. | 登録日 | 2023-02-08 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide. Cell Rep, 43, 2024
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8IAJ
| Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3A) complex | 分子名称: | N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, PYRIDOXAL-5'-PHOSPHATE, Protein ORM2, ... | 著者 | Xie, T, Gong, X. | 登録日 | 2023-02-08 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide. Cell Rep, 43, 2024
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8IAK
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7X31
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7CL0
| Crystal structure of human SIRT6 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ... | 著者 | Song, K, Zhang, J. | 登録日 | 2020-07-20 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Reply to: Binding site for MDL-801 on SIRT6. Nat.Chem.Biol., 17, 2021
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7CL1
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7YG6
| Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA | 分子名称: | MAGNESIUM ION, Piwi, piRNA | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | 登録日 | 2022-07-11 | 公開日 | 2024-01-24 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
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7YES
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7YET
| The structure of EBOV L-VP35 in complex with suramin | 分子名称: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Polymerase cofactor VP35, RNA-directed RNA polymerase L | 著者 | Shi, Y, Yuan, B, Peng, Q. | 登録日 | 2022-07-06 | 公開日 | 2022-10-05 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the Ebola virus polymerase complex. Nature, 610, 2022
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7YER
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4E90
| Human phosphodiesterase 9 in complex with inhibitors | 分子名称: | 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | 著者 | Liu, S. | 登録日 | 2012-03-20 | 公開日 | 2013-02-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Application of structure-based drug design and parallel chemistry to identify selective, brain penetrant, in vivo active phosphodiesterase 9A inhibitors. J.Med.Chem., 55, 2012
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