7X4M
| Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10, 2E6 and 9A3) | Descriptor: | 8A10 heavy chain, 8A10 light chain, Capsid protein VP4, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-02 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
7X47
| Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 2E6 (classified from CVB1 mature virion in complex with 8A10 and 2E6) | Descriptor: | 2E6 heavy chain, 2E6 light chain, Genome polyprotein, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-02 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
7X46
| Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 2E6 (classified from CVB1 mature virion in complex with 8A10 and 2E6) | Descriptor: | 2E6 heavy chain, 2E6 light chain, VP2, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-02 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
7X3F
| Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 9A3 (CVB1-A:9A3) | Descriptor: | 9A3 heavy chain, 9A3 light chain, VP2, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-28 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
7X2O
| Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 2E6 (CVB1-M:2E6) | Descriptor: | 2E6 heavy chain, 2E6 light chain, Capsid protein VP4, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-25 | Release date: | 2022-09-28 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
7X2T
| Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (CVB1-M:8A10) | Descriptor: | 8A10 heavy chain, 8A10 light chain, Capsid protein VP4, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-26 | Release date: | 2022-09-28 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
7X4K
| Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (classified from CVB1 mature virion in complex with 8A10 and 9A3) | Descriptor: | 9A3 heavy chain, 9A3 light chain, Genome polyprotein, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-02 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
7X3D
| Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 9A3 (CVB1-M:9A3) | Descriptor: | 9A3 heavy chain, 9A3 light chain, Capsid protein VP4, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-28 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
8IFY
| Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 spike protein in complex with white-tailed deer ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | Authors: | Han, P, Meng, Y.M, Qi, J.X. | Deposit date: | 2023-02-20 | Release date: | 2023-08-30 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity. J.Virol., 97, 2023
|
|
7X3C
| Cryo-EM structure of Coxsackievirus B1 muture virion in complex with nAbs 8A10 and 5F5 (CVB1-M:8A10:5F5) | Descriptor: | 5F5 heavy chain, 5F5 light chain, 8A10 heavy chain, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-28 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
7X38
| Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 8A10 (CVB1-E:8A10) | Descriptor: | 8A10 heavy chain, 8A10 light chain, VP2, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-28 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
7X42
| Cryo-EM structure of Coxsackievirus B1 pre-A-particle in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10 and 2E6) | Descriptor: | 8A10 heavy chain, 8A10 light chain, Capsid protein VP0, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-01 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
8IL0
| Crystal structure of LmbT from Streptomyces lincolnensis NRRL ISP-5355 | Descriptor: | Glycosyltransferase | Authors: | Dai, Y, Li, P, Qiao, H, Xia, M, Liu, W, Fang, P. | Deposit date: | 2023-03-01 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis. Acs Chem.Biol., 18, 2023
|
|
8ILA
| Crystal structure of LmbT from Streptomyces lincolnensis NRRL ISP-5355 in complex with substrates | Descriptor: | (2~{S})-3-[2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-[(1~{R},2~{R})-1-azanyl-2-oxidanyl-propyl]-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanyl-1~{H}-imidazol-5-yl]-2-(trimethyl-$l^{4}-azanyl)propanoic acid, GUANOSINE-5'-DIPHOSPHATE, Glycosyltransferase | Authors: | Dai, Y, Qiao, H, Xia, M, Fang, P, Liu, W. | Deposit date: | 2023-03-03 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis. Acs Chem.Biol., 18, 2023
|
|
7WRH
| Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Han, P, Xie, Y, Qi, J. | Deposit date: | 2022-01-26 | Release date: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s. Cell Discov, 8, 2022
|
|
8IM7
| Human gamma-secretase treated with ganglioside GM1 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhou, R, Yang, G, Shi, Y. | Deposit date: | 2023-03-06 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Preferential Regulation of Gamma-Secretase-Mediated Cleavage of APP by Ganglioside GM1 Reveals a Potential Therapeutic Target for Alzheimer's Disease. Adv Sci, 10, 2023
|
|
8IT9
| Co-crystal structure of FTO bound to 22 | Descriptor: | 2-OXOGLUTARIC ACID, 2-[(2,6-diethyl-4-pyridin-4-yl-phenyl)amino]-6-(1,4-oxazepan-4-ylmethyl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO | Authors: | Yang, C.-G, Gan, J.H. | Deposit date: | 2023-03-22 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties. J.Med.Chem., 66, 2023
|
|
3VOD
| Crystal Structure of mutant MarR C80S from E.coli | Descriptor: | Multiple antibiotic resistance protein marR | Authors: | Lou, H, Zhu, R, Hao, Z. | Deposit date: | 2012-01-21 | Release date: | 2013-03-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The multiple antibiotic resistance regulator MarR is a copper sensor in Escherichia coli. Nat.Chem.Biol., 10, 2014
|
|
3WD5
| Crystal structure of TNFalpha in complex with Adalimumab Fab fragment | Descriptor: | Adalimumab Heavy Chain, Adalimumab Light Chain, Tumor necrosis factor | Authors: | Hu, S, Liang, S.Y, Guo, Y.J, Lou, Z.Y. | Deposit date: | 2013-06-06 | Release date: | 2013-08-14 | Last modified: | 2015-07-01 | Method: | X-RAY DIFFRACTION (3.101 Å) | Cite: | Comparison of the inhibition mechanisms of adalimumab and infliximab in treating tumor necrosis factor alpha-associated diseases from a molecular view J.Biol.Chem., 288, 2013
|
|
7F6L
| Crystal structure of human MUS81-EME2 complex | Descriptor: | Crossover junction endonuclease MUS81, Probable crossover junction endonuclease EME2 | Authors: | Hua, Z.K, Zhang, D.P, Yuan, C, Lin, Z.H. | Deposit date: | 2021-06-25 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of the human MUS81-EME2 complex. Structure, 30, 2022
|
|
5XN3
| |
1ZGK
| 1.35 angstrom structure of the Kelch domain of Keap1 | Descriptor: | Kelch-like ECH-associated protein 1 | Authors: | Li, X, Bottoms, C.A, Hannink, M, Beamer, L.J. | Deposit date: | 2005-04-21 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Conserved solvent and side-chain interactions in the 1.35 Angstrom structure of the Kelch domain of Keap1. Acta Crystallogr.,Sect.D, 61, 2005
|
|
5YZ9
| zinc finger domain of METTL3-METTL14 N6-methyladenosine methyltransferase | Descriptor: | N6-adenosine-methyltransferase catalytic subunit, ZINC ION | Authors: | Dong, X, Tang, C, Gong, Z, Yin, P, Huang, J.B. | Deposit date: | 2017-12-13 | Release date: | 2018-03-28 | Last modified: | 2019-03-27 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase. Protein Cell, 10, 2019
|
|
4G3Y
| Crystal structure of TNF-alpha in complex with Infliximab Fab fragment | Descriptor: | Tumor necrosis factor, infliximab Fab H, infliximab Fab L | Authors: | Liang, S.Y, Dai, J.X, Guo, Y.J, Lou, Z.Y. | Deposit date: | 2012-07-15 | Release date: | 2013-03-27 | Last modified: | 2013-08-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for treating tumor necrosis factor alpha (TNFalpha)-associated diseases with the therapeutic antibody infliximab J.Biol.Chem., 288, 2013
|
|
4JBA
| |