7T5G
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![BU of 7t5g by Molmil](/molmil-images/mine/7t5g) | Structure of rabies virus phosphoprotein C-terminal domain, S210E mutant | Descriptor: | Phosphoprotein, SULFATE ION | Authors: | Zhan, J, Metcalfe, R.D, Gooley, P.R, Griffin, M.D.W. | Deposit date: | 2021-12-12 | Release date: | 2022-04-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular Basis of Functional Effects of Phosphorylation of the C-Terminal Domain of the Rabies Virus P Protein. J.Virol., 96, 2022
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7T5H
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![BU of 7t5h by Molmil](/molmil-images/mine/7t5h) | Structure of rabies virus phosphoprotein C-terminal domain, wild type | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Phosphoprotein, ... | Authors: | Zhan, J, Metcalfe, R.D, Gooley, P.R, Griffin, M.D.W. | Deposit date: | 2021-12-12 | Release date: | 2022-04-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Molecular Basis of Functional Effects of Phosphorylation of the C-Terminal Domain of the Rabies Virus P Protein. J.Virol., 96, 2022
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8CX3
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![BU of 8cx3 by Molmil](/molmil-images/mine/8cx3) | Crystal structure of full-length mesothelin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Zhan, J, Esser, L, Xia, D. | Deposit date: | 2022-05-19 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.609 Å) | Cite: | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies. Cancer Res Commun, 3, 2023
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7WKJ
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![BU of 7wkj by Molmil](/molmil-images/mine/7wkj) | A COVID-19 T-cell response detection method based on a newly identified human CD8+ T cell epitope from SARS-CoV-2-Hubei Province, 2021. | Descriptor: | Beta-2-microglobulin, LYS-THR-PHE-PRO-PRO-THR-GLU-PRO-LYS, MHC class I antigen | Authors: | Zhang, J, Lu, D, Li, M, Liu, M.S, Yao, S.J, Zhan, J.B, Liu, J, Gao, G.F. | Deposit date: | 2022-01-10 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A COVID-19 T-Cell Response Detection Method Based on a Newly Identified Human CD8 + T Cell Epitope from SARS-CoV-2 - Hubei Province, China, 2021. China CDC Wkly, 4, 2022
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7U9J
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![BU of 7u9j by Molmil](/molmil-images/mine/7u9j) | Crystal structure of Mesothelin-207 fragment | Descriptor: | GLYCEROL, Isoform 3 of Mesothelin, SULFATE ION | Authors: | Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D. | Deposit date: | 2022-03-10 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies. Cancer Res Commun, 3, 2023
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7UED
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![BU of 7ued by Molmil](/molmil-images/mine/7ued) | Crystal structure of full length mesothelin bound with MORAb-009 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Isoform 4 of Mesothelin, ... | Authors: | Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D. | Deposit date: | 2022-03-21 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies. Cancer Res Commun, 3, 2023
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8TBY
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![BU of 8tby by Molmil](/molmil-images/mine/8tby) | Apo Bcs1, unsymmetrized | Descriptor: | Mitochondrial chaperone BCS1 | Authors: | Zhan, J, Xia, D. | Deposit date: | 2023-06-29 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8T5U
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![BU of 8t5u by Molmil](/molmil-images/mine/8t5u) | ATP-1 state of Bcs1 (C7 symmetrized) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | Authors: | Zhan, J, Xia, D. | Deposit date: | 2023-06-14 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8T14
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![BU of 8t14 by Molmil](/molmil-images/mine/8t14) | ADP-bound Bcs1 (C7 symmetrized) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1 | Authors: | Zhan, J, Xia, D. | Deposit date: | 2023-06-01 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8T7U
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![BU of 8t7u by Molmil](/molmil-images/mine/8t7u) | ADP-bound Bcs1 (unsymmetrized) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1 | Authors: | Zhan, J, Xia, D. | Deposit date: | 2023-06-21 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8TI0
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![BU of 8ti0 by Molmil](/molmil-images/mine/8ti0) | ATP-1 state of Bcs1 (unsymmetrized) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | Authors: | Zhan, J, Xia, D. | Deposit date: | 2023-07-18 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8TPL
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![BU of 8tpl by Molmil](/molmil-images/mine/8tpl) | ATP-2 state of Bcs1 (unsymmetrized) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | Authors: | Zhan, J, Xia, D. | Deposit date: | 2023-08-04 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8TP1
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![BU of 8tp1 by Molmil](/molmil-images/mine/8tp1) | ATP-2 state of Bcs1 (C7 symmetrized) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | Authors: | Zhan, J, Xia, D. | Deposit date: | 2023-08-04 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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5D6Q
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![BU of 5d6q by Molmil](/molmil-images/mine/5d6q) | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-{4-[(E)-2-(pyridin-3-yl)ethenyl]-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl}urea, DNA gyrase subunit B, ... | Authors: | Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. | Deposit date: | 2015-08-12 | Release date: | 2015-11-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors. J.Med.Chem., 58, 2015
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5D7C
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![BU of 5d7c by Molmil](/molmil-images/mine/5d7c) | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[1-(pyridin-2-yl)-6-(pyridin-3-yl)-1H-pyrrolo[3,2-b]pyridin-3-yl]urea, DNA gyrase subunit B, ... | Authors: | Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. | Deposit date: | 2015-08-13 | Release date: | 2015-11-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors. J.Med.Chem., 58, 2015
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5D7D
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![BU of 5d7d by Molmil](/molmil-images/mine/5d7d) | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 7-propyl-3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, CHLORIDE ION, ... | Authors: | Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. | Deposit date: | 2015-08-13 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors. Acs Med.Chem.Lett., 6, 2015
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5D7R
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![BU of 5d7r by Molmil](/molmil-images/mine/5d7r) | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-hydroxy-5-[5-(6-hydroxy-7-propyl-2H-indazol-3-yl)-1,3-thiazol-2-yl]pyridine-2-carboxylic acid, CHLORIDE ION, ... | Authors: | Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. | Deposit date: | 2015-08-14 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors. Acs Med.Chem.Lett., 6, 2015
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8W8D
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![BU of 8w8d by Molmil](/molmil-images/mine/8w8d) | |
7WNW
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![BU of 7wnw by Molmil](/molmil-images/mine/7wnw) | |
4TZW
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![BU of 4tzw by Molmil](/molmil-images/mine/4tzw) | Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate and replacing Mg2+ with Sr2+ post crystallization | Descriptor: | Ribosome-associated protein L7Ae-like, STRONTIUM ION, T-box Stem I, ... | Authors: | Zhang, J, Ferre-D'Amare, A.R. | Deposit date: | 2014-07-11 | Release date: | 2014-09-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (4.671 Å) | Cite: | Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration. Structure, 22, 2014
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4TZP
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![BU of 4tzp by Molmil](/molmil-images/mine/4tzp) | As Grown, Untreated Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its cognate tRNAGly, and B. subtilis YbxF protein | Descriptor: | Ribosome-associated protein L7Ae-like, engineered tRNA, glyQ T-box Stem I | Authors: | Zhang, J, Ferre-D'Amare, A.R. | Deposit date: | 2014-07-10 | Release date: | 2014-09-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (8.503 Å) | Cite: | Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration. Structure, 22, 2014
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4TZV
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![BU of 4tzv by Molmil](/molmil-images/mine/4tzv) | Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate post crystallization | Descriptor: | Ribosome-associated protein L7Ae-like, T-box stem I, engineered tRNA | Authors: | Zhang, J, Ferre-D'Amare, A.R. | Deposit date: | 2014-07-11 | Release date: | 2014-09-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (5.03 Å) | Cite: | Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration. Structure, 22, 2014
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5D6P
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![BU of 5d6p by Molmil](/molmil-images/mine/5d6p) | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[4-(hydroxymethyl)-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl]urea, DNA gyrase subunit B, ... | Authors: | Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. | Deposit date: | 2015-08-12 | Release date: | 2015-11-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors. J.Med.Chem., 58, 2015
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1Y5R
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![BU of 1y5r by Molmil](/molmil-images/mine/1y5r) | The crystal structure of murine 11b-hydroxysteroid dehydrogenase complexed with corticosterone | Descriptor: | CORTICOSTERONE, Corticosteroid 11-beta-dehydrogenase, isozyme 1, ... | Authors: | Zhang, J, Osslund, T.D, Plant, M.H, Clogston, C.L, Nybo, R.E, Xiong, F, Delaney, J.M, Jordan, S. | Deposit date: | 2004-12-02 | Release date: | 2005-05-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of Murine 11-Hydroxysteroid Dehydrogenase 1: An Important Therapeutic Target for Diabetes Biochemistry, 44, 2005
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1Y5M
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![BU of 1y5m by Molmil](/molmil-images/mine/1y5m) | The crystal structure of murine 11b-hydroxysteroid dehydrogenase: an important therapeutic target for diabetes | Descriptor: | Corticosteroid 11-beta-dehydrogenase, isozyme 1, N-OCTANE, ... | Authors: | Zhang, J, Osslund, T.D, Plant, M.H, Clogston, C.L, Nybo, R.E, Xiong, F, Delaney, J.M, Jordan, S.R. | Deposit date: | 2004-12-02 | Release date: | 2005-05-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Murine 11-Hydroxysteroid Dehydrogenase 1: An Important Therapeutic Target for Diabetes Biochemistry, 44, 2005
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