1WUG
 
 | | complex structure of PCAF bromodomain with small chemical ligand NP1 | | 分子名称: | Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-4-METHYL-2-NITROBENZENAMINE | | 著者 | Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M. | | 登録日 | 2004-12-07 | | 公開日 | 2005-08-16 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
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1WUM
 | | Complex structure of PCAF bromodomain with small chemical ligand NP2 | | 分子名称: | Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-2-NITROBENZENAMINE | | 著者 | Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M. | | 登録日 | 2004-12-08 | | 公開日 | 2005-08-16 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
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1ZS5
 | | Structure-based evaluation of selective and non-selective small molecules that block HIV-1 TAT and PCAF association | | 分子名称: | (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE, Histone acetyltransferase PCAF | | 著者 | Zeng, L, Godbole, S, Muller, M, Yan, S, Sanchez, R, Zhou, M. | | 登録日 | 2005-05-23 | | 公開日 | 2006-05-23 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure-based evaluation of selective nad non-selective small molecules that block hiv-1 tat and pcaf association
TO BE PUBLISHED
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2KWJ
 | | Solution structures of the double PHD fingers of human transcriptional protein DPF3 bound to a histone peptide containing acetylation at lysine 14 | | 分子名称: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | | 著者 | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | | 登録日 | 2010-04-12 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
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2KWO
 | | Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing N-terminal acetylation at Serine 1 | | 分子名称: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | | 著者 | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | | 登録日 | 2010-04-14 | | 公開日 | 2010-07-14 | | 最終更新日 | 2013-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
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2KWN
 | | Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing acetylation at Lysine 16 | | 分子名称: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | | 著者 | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | | 登録日 | 2010-04-13 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
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2KWK
 | | Solution structures of the double PHD fingers of human transcriptional protein DPF3b bound to a H3 peptide wild type | | 分子名称: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | | 著者 | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | | 登録日 | 2010-04-12 | | 公開日 | 2010-07-14 | | 最終更新日 | 2013-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
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2L5D
 | | Solution Structures of human PIWI-like 1 PAZ domain with ssRNA (5'-pUGACA) | | 分子名称: | 5'-R(*UP*GP*AP*CP*A)-3', Piwi-like protein 1 | | 著者 | Zeng, L, Zhang, Q, Yan, K, Zhou, M. | | 登録日 | 2010-10-29 | | 公開日 | 2011-04-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain.
Proteins, 79, 2011
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2L5C
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3VJ6
 | | Structure of the MHC class Ib molecule Qa-1b | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-37 alpha chain, ... | | 著者 | Zeng, L, Clements, C.S, Rossjohn, J. | | 登録日 | 2011-10-12 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A structural basis for antigen presentation by the MHC class Ib molecule, Qa-1b
J.Immunol., 188, 2012
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2MFQ
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2RO1
 | | NMR Solution Structures of Human KAP1 PHD finger-bromodomain | | 分子名称: | Transcription intermediary factor 1-beta, ZINC ION | | 著者 | Zeng, L, Yap, K.L, Ivanov, A.V, Wang, X, Mujtaba, S, Plotnikova, O, Rauscher, F.J. | | 登録日 | 2008-03-04 | | 公開日 | 2008-05-20 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing
Nat.Struct.Mol.Biol., 15, 2008
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2RNW
 | | The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the Human Transcriptional Co-Activators PCAf and CBP | | 分子名称: | Histone H3, Histone acetyltransferase PCAF | | 著者 | Zeng, L, Zhang, Q, Gerona-Navarro, G, Zhou, M.M. | | 登録日 | 2008-02-03 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300
Structure, 16, 2008
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2RNX
 | | The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the HUman Transcriptional Co-Activators PCAF and CBP | | 分子名称: | Histone H3, Histone acetyltransferase PCAF | | 著者 | Zeng, L, Zhang, Q, Gerona-Navarro, G, Zhou, M.M. | | 登録日 | 2008-02-03 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300
Structure, 16, 2008
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2RNY
 | | Complex Structures of CBP Bromodomain with H4 ack20 Peptide | | 分子名称: | CREB-binding protein, Histone H4 | | 著者 | Zeng, L, Zhang, Q, Gerona-Navarro, G, Zhou, M.M. | | 登録日 | 2008-02-03 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300
Structure, 16, 2008
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2MJV
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2NDF
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2NDG
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2ND0
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2NCZ
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2ND1
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5U5S
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7WWZ
 | | BRD4-BD1 complexed with NEO2734 | | 分子名称: | 1,3-dimethyl-5-[2-(oxan-4-yl)-3-[2-(trifluoromethyloxy)ethyl]benzimidazol-5-yl]pyridin-2-one, Isoform C of Bromodomain-containing protein 4 | | 著者 | Zeng, L, Lei, J.D. | | 登録日 | 2022-02-14 | | 公開日 | 2022-06-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | Targeting CDCP1 gene transcription coactivated by BRD4 and CBP/p300 in castration-resistant prostate cancer.
Oncogene, 41, 2022
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7WX2
 | | CBP-BrD complexed with NEO2734 | | 分子名称: | 1,3-dimethyl-5-[2-(oxan-4-yl)-3-[2-(trifluoromethyloxy)ethyl]benzimidazol-5-yl]pyridin-2-one, CREB-binding protein | | 著者 | Zeng, L, Lei, J.D. | | 登録日 | 2022-02-14 | | 公開日 | 2022-06-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Targeting CDCP1 gene transcription coactivated by BRD4 and CBP/p300 in castration-resistant prostate cancer.
Oncogene, 41, 2022
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5Z9C
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