2IXB
| Crystal structure of N-ACETYLGALACTOSAMINIDASE in complex with GalNAC | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, ... | 著者 | Sulzenbacher, G, Liu, Q.P, Bourne, Y, Henrissat, B, Clausen, H. | 登録日 | 2006-07-07 | 公開日 | 2007-04-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Bacterial Glycosidases for the Production of Universal Red Blood Cells. Nat.Biotechnol., 25, 2007
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5GZR
| Zika virus E protein complexed with a neutralizing antibody Z23-Fab | 分子名称: | Z23 Fab heavy chain, Z23 Fab light chain, structural protein E, ... | 著者 | Gao, G.G, Shi, Y, Peng, R, Liu, S. | 登録日 | 2016-10-01 | 公開日 | 2016-11-30 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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5IMX
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8HF8
| Human PPAR delta ligand binding domain in complex with a synthetic agonist V1 | 分子名称: | 2-[4-[[2,5-bis(oxidanylidene)-3-[4-(trifluoromethyl)phenyl]imidazolidin-1-yl]methyl]-2,6-dimethyl-phenoxy]-2-methyl-propanoic acid, Peroxisome proliferator-activated receptor delta, octyl beta-D-glucopyranoside | 著者 | Dai, L, Sun, H.B, Yuan, H.L, Feng, Z.Q. | 登録日 | 2022-11-09 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Discovery of the First Subnanomolar PPAR alpha / delta Dual Agonist for the Treatment of Cholestatic Liver Diseases. J.Med.Chem., 66, 2023
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7DL2
| Cryo-EM structure of human TSC complex | 分子名称: | Hamartin, Isoform 7 of Tuberin, TBC1 domain family member 7, ... | 著者 | Yang, H, Yu, Z, Chen, X, Li, J, Li, N, Cheng, J, Gao, N, Yuan, H, Ye, D, Guan, K, Xu, Y. | 登録日 | 2020-11-25 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural insights into TSC complex assembly and GAP activity on Rheb. Nat Commun, 12, 2021
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6M1K
| USP7 in complex with a novel inhibitor | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 7, methyl 4-[[4-[[3-[4-(aminomethyl)phenyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-6-yl]methyl]-4-oxidanyl-piperidin-1-yl]methyl]-3-chloranyl-benzoate | 著者 | Liu, S.J, Zhou, X.Y, Li, M.L, Sun, H.B, Wen, X.A. | 登録日 | 2020-02-26 | 公開日 | 2021-03-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.255 Å) | 主引用文献 | N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies. Eur.J.Med.Chem., 199, 2020
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5IVL
| CshA Helicase | 分子名称: | DEAD-box ATP-dependent RNA helicase CshA, SULFATE ION | 著者 | Huen, J, Lin, C.-L, Yi, W.-L, Li, C.-L, Yuan, H. | 登録日 | 2016-03-21 | 公開日 | 2017-03-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Insights into a Unique Dimeric DEAD-Box Helicase CshA that Promotes RNA Decay. Structure, 25, 2017
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7W0G
| Human PPAR delta ligand binding domain in complex with a synthetic agonist H11 | 分子名称: | 2-[2,6-dimethyl-4-[[5-oxidanylidene-4-[4-(trifluoromethyloxy)phenyl]-1,2,4-triazol-1-yl]methyl]phenoxy]-2-methyl-propanoic acid, Peroxisome proliferator-activated receptor delta | 著者 | Dai, L, Sun, H.B, Yuan, H.L, Feng, Z.Q. | 登録日 | 2021-11-18 | 公開日 | 2022-02-02 | 最終更新日 | 2022-02-23 | 実験手法 | X-RAY DIFFRACTION (2.443 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPAR alpha / delta Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis. J.Med.Chem., 65, 2022
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4PBP
| crystal structure of zebrafish short-chain pentraxin protein | 分子名称: | C-reactive protein, CALCIUM ION, GLYCEROL | 著者 | Chen, R, Qi, J.X, George, F.G, Xia, C. | 登録日 | 2014-04-13 | 公開日 | 2015-03-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | 主引用文献 | Crystal structures for short-chain pentraxin from zebrafish demonstrate a cyclic trimer with new recognition and effector faces. J.Struct.Biol., 189, 2015
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4PBO
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4Q4K
| Crystal structure of nitronate monooxygenase from Pseudomonas aeruginosa PAO1 | 分子名称: | FLAVIN MONONUCLEOTIDE, Nitronate Monooxygenase | 著者 | Salvi, F, Agniswamy, J, Gadda, G, Weber, I.T. | 登録日 | 2014-04-14 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | The Combined Structural and Kinetic Characterization of a Bacterial Nitronate Monooxygenase from Pseudomonas aeruginosa PAO1 Establishes NMO Class I and II. J.Biol.Chem., 289, 2014
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4QAS
| 1.27 A resolution structure of CT263-D161N (MTAN) from Chlamydia trachomatis | 分子名称: | CT263, SULFATE ION | 著者 | Barta, M.L, Thomas, K, Lovell, S, Battaile, K.P, Schramm, V.L, Hefty, P.S. | 登録日 | 2014-05-05 | 公開日 | 2014-10-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural and Biochemical Characterization of Chlamydia trachomatis Hypothetical Protein CT263 Supports That Menaquinone Synthesis Occurs through the Futalosine Pathway. J.Biol.Chem., 289, 2014
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4QAQ
| 1.58 A resolution structure of CT263 (MTAN) from Chlamydia trachomatis | 分子名称: | CT263, SULFATE ION | 著者 | Barta, M.L, Thomas, K, Lovell, S, Battaile, K.P, Schramm, V.L, Hefty, P.S. | 登録日 | 2014-05-05 | 公開日 | 2014-10-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Structural and Biochemical Characterization of Chlamydia trachomatis Hypothetical Protein CT263 Supports That Menaquinone Synthesis Occurs through the Futalosine Pathway. J.Biol.Chem., 289, 2014
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4QFB
| 1.99 A resolution structure of SeMet-CT263 (MTAN) from Chlamydia trachomatis | 分子名称: | CT263 | 著者 | Barta, M.L, Thomas, K, Lovell, S, Battaile, K.P, Schramm, V.L, Hefty, P.S. | 登録日 | 2014-05-20 | 公開日 | 2014-10-01 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | 主引用文献 | Structural and Biochemical Characterization of Chlamydia trachomatis Hypothetical Protein CT263 Supports That Menaquinone Synthesis Occurs through the Futalosine Pathway. J.Biol.Chem., 289, 2014
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4QAT
| 1.75 A resolution structure of CT263-D161N (MTAN) from Chlamydia trachomatis bound to MTA | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CT263 | 著者 | Barta, M.L, Thomas, K, Lovell, S, Battaile, K.P, Schramm, V.L, Hefty, P.S. | 登録日 | 2014-05-05 | 公開日 | 2014-10-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and Biochemical Characterization of Chlamydia trachomatis Hypothetical Protein CT263 Supports That Menaquinone Synthesis Occurs through the Futalosine Pathway. J.Biol.Chem., 289, 2014
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4QAR
| 1.45 A resolution structure of CT263 (MTAN) from Chlamydia trachomatis bound to Adenine | 分子名称: | ADENINE, CT263, SULFATE ION | 著者 | Barta, M.L, Thomas, K, Lovell, S, Battaile, K.P, Schramm, V.L, Hefty, P.S. | 登録日 | 2014-05-05 | 公開日 | 2014-10-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural and Biochemical Characterization of Chlamydia trachomatis Hypothetical Protein CT263 Supports That Menaquinone Synthesis Occurs through the Futalosine Pathway. J.Biol.Chem., 289, 2014
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3DBG
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3EL3
| Distinct Monooxygenase and Farnesene Synthase Active Sites in Cytochrome P450 170A1 | 分子名称: | (3S,3aR,6S)-3,7,7,8-tetramethyl-2,3,4,5,6,7-hexahydro-1H-3a,6-methanoazulene, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 | 著者 | Zhao, B, Waterman, M.R. | 登録日 | 2008-09-19 | 公開日 | 2009-09-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site J.Biol.Chem., 284, 2009
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7C6O
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3GV3
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3NYE
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8H56
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3SM8
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2NZA
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2NZ5
| Structure and Function Studies of Cytochrome P450 158A1 from Streptomyces coelicolor A3(2) | 分子名称: | Cytochrome P450 CYP158A1, PROTOPORPHYRIN IX CONTAINING FE, naphthalene-1,2,4,5,7-pentol | 著者 | Zhao, B, Lamb, D.C, Kelly, S.L, Waterman, M.R. | 登録日 | 2006-11-22 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2. Biochemistry, 46, 2007
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