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Crystal structure of the aminoacylation catalytic fragment of human tryptophanyl-tRNA synthetase
分子名称:	Tryptophanyl-tRNA synthetase
著者	Yu, Y, Liu, Y, Shen, N, Xu, X, Jia, J, Jin, Y, Arnold, E, Ding, J.
登録日	2003-10-05
公開日	2004-07-06
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Crystal Structure of Human Tryptophanyl-tRNA Synthetase Catalytic Fragment J.BIOL.CHEM., 279, 2004

1XTQ

Structure of small GTPase human Rheb in complex with GDP
分子名称:	GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者	Yu, Y, Ding, J.
登録日	2004-10-24
公開日	2005-03-08
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structural Basis for the Unique Biological Function of Small GTPase RHEB J.Biol.Chem., 280, 2005

1XTS

Structure of small GTPase human Rheb in complex with GTP
分子名称:	GTP-binding protein Rheb, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者	Yu, Y, Ding, J.
登録日	2004-10-24
公開日	2005-03-08
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Structural Basis for the Unique Biological Function of Small GTPase RHEB J.Biol.Chem., 280, 2005

1XTR

Structure of small GTPase human Rheb in complex with GppNHp
分子名称:	GLYCEROL, GTP-binding protein Rheb, MAGNESIUM ION, ...
著者	Yu, Y, Ding, J.
登録日	2004-10-24
公開日	2005-03-08
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.65 Å)
主引用文献	Structural Basis for the Unique Biological Function of Small GTPase RHEB J.Biol.Chem., 280, 2005

3IPM

Crystal Structure of Archaeal 20S Proteasome in Complex with the C-terminus of PAN
分子名称:	Proteasome activator PA26, Proteasome-activating nucleotidase fusion protein, Proteasome subunit alpha, ...
著者	Yu, Y, Cheng, Y.
登録日	2009-08-17
公開日	2009-12-29
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (4 Å)
主引用文献	Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions. Embo J., 29, 2010

7SDE

Cryo-EM structure of Nse5/6 heterodimer
分子名称:	Non-structural maintenance of chromosome element 5, Ubiquitin-like protein SMT3,DNA repair protein KRE29 chimera
著者	Yu, Y, Patel, D.J, Zhao, X.L.
登録日	2021-09-29
公開日	2021-10-13
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	The cryo-EM structure of Nse5/6 complex with the C terminal part of Nse5 To Be Published

7VYU

Crystal structure of NatS
分子名称:	3-oxoacyl-ACP synthase
著者	Yu, Y, He, C, Wu, L, Zhang, Y.
登録日	2021-11-15
公開日	2022-08-24
最終更新日	2023-03-15
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Crystal structure of NatS To Be Published

4B2H

COMPLEXES OF DODECIN WITH FLAVIN AND FLAVIN-LIKE LIGANDS
分子名称:	3-[7,8-dimethyl-2,4-bis(oxidanylidene)benzo[g]pteridin-10-yl]propylcarbamic acid, CHLORIDE ION, DODECIN, ...
著者	Yu, Y, Heidel, B, Parapugna, T.L, Wenderhold-Reeb, S, Song, B, Schoenherr, H, Grininger, M, Noell, G.
登録日	2012-07-16
公開日	2013-05-29
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	The Flavoprotein Dodecin as a Redox Probe for Electron Transfer Through DNA. Angew.Chem.Int.Ed.Engl., 52, 2013

4HK4

Crystal structure of apo Tyrosine-tRNA ligase mutant protein
分子名称:	DI(HYDROXYETHYL)ETHER, Tyrosine--tRNA ligase
著者	Yu, Y, Zhou, Q, Dong, J, Li, J, Xiaoxuan, L, Mukherjee, A, Ouyang, H, Nilges, M, Li, H, Gao, F, Gong, W, Lu, Y, Wang, J.
登録日	2012-10-15
公開日	2013-04-17
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.298 Å)
主引用文献	Crystal structure of apo Tyrosine-tRNA ligase mutant protein To be Published

4HPW

Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine
分子名称:	3-methoxy-L-tyrosine, Tyrosine--tRNA ligase
著者	Yu, Y, Zhou, Q, Dong, J, Li, J, Xiaoxuan, L, Mukherjee, A, Ouyang, H, Nilges, M, Li, H, Gao, F, Gong, W, Lu, Y, Wang, J.
登録日	2012-10-24
公開日	2013-10-30
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.998 Å)
主引用文献	Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine To be Published

4M58

Crystal Structure of an transition metal transporter
分子名称:	Cobalamin biosynthesis protein CbiM, NICKEL (II) ION
著者	Yu, Y, Yan, C.Y, Zhang, B, Li, X.L, Gu, J.K.
登録日	2013-08-08
公開日	2014-03-26
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (3.21 Å)
主引用文献	Planar substrate-binding site dictates the specificity of ECF-type nickel/cobalt transporters Cell Res., 24, 2014

4M5B

Crystal Structure of an Truncated Transition Metal Transporter
分子名称:	Cobalamin biosynthesis protein CbiM, HEXANE-1,6-DIOL, NICKEL (II) ION
著者	Yu, Y.
登録日	2013-08-08
公開日	2014-03-26
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (1.833 Å)
主引用文献	Planar substrate-binding site dictates the specificity of ECF-type nickel/cobalt transporters Cell Res., 24, 2014

4M5C

Crystal Structure of an Truncated Transition metal Transporter
分子名称:	COBALT (II) ION, Cobalamin biosynthesis protein CbiM, HEXANE-1,6-DIOL
著者	Yu, Y, Zhou, M.Z, Gu, J.K.
登録日	2013-08-08
公開日	2014-03-26
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Planar substrate-binding site dictates the specificity of ECF-type nickel/cobalt transporters Cell Res., 24, 2014

2G3F

Crystal Structure of imidazolonepropionase complexed with imidazole-4-acetic acid sodium salt, a substrate homologue
分子名称:	2H-IMIDAZOL-4-YLACETIC ACID, Imidazolonepropionase, ZINC ION
著者	Yu, Y, Liang, Y.H, Su, X.D.
登録日	2006-02-19
公開日	2006-09-26
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	A catalytic mechanism revealed by the crystal structures of the imidazolonepropionase from Bacillus subtilis J.Biol.Chem., 281, 2006

3HRO

Crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2)
分子名称:	Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2), also called Polycystin-2 or polycystic kidney disease 2(PKD2)
著者	Yu, Y, Ulbrich, M.H, Li, M.-H, Buraei, Z, Chen, X.-Z, Ong, A.C.M, Tong, L, Isacoff, E.Y, Yang, J.
登録日	2009-06-09
公開日	2009-07-28
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. Proc.Natl.Acad.Sci.USA, 106, 2009

3HRN

crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2)
分子名称:	Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2)
著者	Yu, Y, Ulbrich, M.H, Li, M.-H, Buraei, Z, Chen, X.-Z, Ong, A.C.M, Tong, L, Isacoff, E.Y, Yang, J.
登録日	2009-06-09
公開日	2009-07-28
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. Proc.Natl.Acad.Sci.USA, 106, 2009

7KEO

Crystal structure of K29-linked di-ubiquitin in complex with synthetic antigen binding fragment
分子名称:	PHOSPHATE ION, Synthetic antigen binding fragment, heavy chain, ...
著者	Yu, Y, Zheng, Q, Erramilli, S, Pan, M, Kossiakoff, A, Liu, L, Zhao, M.
登録日	2020-10-11
公開日	2021-07-28
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle. Nat.Chem.Biol., 17, 2021

4GIF

C-terminal coiled-coil domain of transient receptor potential channel TRPP3 (PKD2L1, Polycystin-L)
分子名称:	Polycystic kidney disease 2-like 1 protein
著者	Yu, Y, Ulbrich, M.H, Li, M.-H, Dobbins, S, Zhang, W.K, Tong, L, Isacoff, E.Y, Yang, J.
登録日	2012-08-08
公開日	2012-12-05
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex. Nat Commun, 3, 2012

4IRZ

Crystal structure of A4b7 headpiece complexed with Fab Natalizumab
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者	Yu, Y, Schurpf, T, Springer, T.A.
登録日	2013-01-15
公開日	2013-09-25
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.84 Å)
主引用文献	How natalizumab binds and antagonizes alpha 4 integrins. J.Biol.Chem., 288, 2013

3V4V

crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376
分子名称:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者	Yu, Y, Zhu, J, Springer, T.A.
登録日	2011-12-15
公開日	2012-01-11
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012

3V4P

crystal structure of a4b7 headpiece complexed with Fab ACT-1
分子名称:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者	Yu, Y, Zhu, J, Springer, T.A.
登録日	2011-12-15
公開日	2012-01-11
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (3.15 Å)
主引用文献	Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012

7TVE

ATP and DNA bound SMC5/6 core complex
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, DNA (68-MER), DNA (78-MER), ...
著者	Yu, Y, Patel, D.J.
登録日	2022-02-04
公開日	2022-06-22
最終更新日	2024-02-21
実験手法	ELECTRON MICROSCOPY (3.8 Å)
主引用文献	Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes. Proc.Natl.Acad.Sci.USA, 119, 2022

7LTO

Nse5-6 complex
分子名称:	Non-structural maintenance of chromosome element 5, Ubiquitin-like protein SMT3,DNA repair protein KRE29 chimera
著者	Yu, Y, Li, S.B, Zheng, S, Tangy, S, Koyi, C, Wan, B.B, Kung, H.H, Andrej, S, Alex, K, Patel, D.J, Zhao, X.L.
登録日	2021-02-19
公開日	2021-05-19
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Integrative analysis reveals unique structural and functional features of the Smc5/6 complex. Proc.Natl.Acad.Sci.USA, 118, 2021

7DQW

E. coli GyrB ATPase domain in complex with 4-chlorophenol
分子名称:	1H-benzimidazol-2-amine, 4-chlorophenol, DNA gyrase subunit B, ...
著者	Yu, Y, Zhou, H.
登録日	2020-12-24
公開日	2021-10-27
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.88 Å)
主引用文献	Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021

7DPS

E. coli GyrB ATPase domain in complex with Methyl 4-hydroxycinnamate
分子名称:	1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ...
著者	Yu, Y, Zhou, H.
登録日	2020-12-21
公開日	2021-10-27
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.26 Å)
主引用文献	Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021

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