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7YR2
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BU of 7yr2 by Molmil
SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Wang, L.
Deposit date:2022-08-08
Release date:2022-10-19
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
7YQX
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BU of 7yqx by Molmil
SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, ...
Authors:Wang, L.
Deposit date:2022-08-08
Release date:2022-10-19
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
7VQ6
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BU of 7vq6 by Molmil
Structure of a specialized glyoxalase from Gossypium hirsutum
Descriptor: Lactoylglutathione lyase, NICKEL (II) ION
Authors:Li, H, Hu, Y.M, Dai, L.H, Chen, C.C, Huang, J.W, Liu, W.D, Guo, R.T.
Deposit date:2021-10-19
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Crystal structure and biochemical analysis of the specialized deoxynivalenol-detoxifying glyoxalase SPG from Gossypium hirsutum.
Int.J.Biol.Macromol., 200, 2022
7ENE
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BU of 7ene by Molmil
Crystal structure of MERS-CoV 3CLpro in complex with the non-covalent inhibitor WU-04
Descriptor: ORF1a protein, ~{N}-[(1~{S},2~{R})-2-[[4-bromanyl-2-(methylcarbamoyl)-6-nitro-phenyl]amino]cyclohexyl]isoquinoline-4-carboxamide
Authors:Hou, N, Peng, C, Hu, Q.
Deposit date:2021-04-16
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro.
Acs Cent.Sci., 9, 2023
7EN9
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BU of 7en9 by Molmil
Crystal structure of SARS-CoV-2 3CLpro in complex with the non-covalent inhibitor WU-02
Descriptor: 3C-like proteinase, 5-bromanyl-~{N}-methyl-3-nitro-2-[(4~{R},5~{S})-2-(7-oxidanylisoquinolin-4-yl)carbonyl-4-phenyl-2,7-diazaspiro[4.4]nonan-7-yl]benzamide
Authors:Hou, N, Peng, C, Hu, Q.
Deposit date:2021-04-16
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro.
Acs Cent.Sci., 9, 2023
7EN8
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BU of 7en8 by Molmil
Crystal structure of SARS-CoV-2 3CLpro in complex with the non-covalent inhibitor WU-04
Descriptor: 3C-like proteinase, GLYCEROL, ~{N}-[(1~{S},2~{R})-2-[[4-bromanyl-2-(methylcarbamoyl)-6-nitro-phenyl]amino]cyclohexyl]isoquinoline-4-carboxamide
Authors:Hou, N, Peng, C, Hu, Q.
Deposit date:2021-04-16
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro.
Acs Cent.Sci., 9, 2023
7END
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BU of 7end by Molmil
Crystal structure of SARS-CoV 3CLpro in complex with the non-covalent inhibitor WU-04
Descriptor: Replicase polyprotein 1a, ~{N}-[(1~{S},2~{R})-2-[[4-bromanyl-2-(methylcarbamoyl)-6-nitro-phenyl]amino]cyclohexyl]isoquinoline-4-carboxamide
Authors:Hou, N, Peng, C, Hu, Q.
Deposit date:2021-04-16
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro.
Acs Cent.Sci., 9, 2023
4IP8
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BU of 4ip8 by Molmil
Structure of human serum amyloid A1
Descriptor: O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, SULFATE ION, Serum amyloid A-1 protein
Authors:Lu, J, Sun, P.D.
Deposit date:2013-01-09
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.193 Å)
Cite:Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
Proc.Natl.Acad.Sci.USA, 111, 2014
4IP9
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BU of 4ip9 by Molmil
Structure of native human serum amyloid A1
Descriptor: O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Serum amyloid A-1 protein
Authors:Lu, J, Sun, P.D.
Deposit date:2013-01-09
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
Proc.Natl.Acad.Sci.USA, 111, 2014
3ME3
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BU of 3me3 by Molmil
Activator-Bound Structure of Human Pyruvate Kinase M2
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, 3-{[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl}aniline, Pyruvate kinase isozymes M1/M2, ...
Authors:Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Nat.Chem.Biol., 8, 2012
8J48
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BU of 8j48 by Molmil
Crystal structure of OY phytoplasma SAP05 in complex with AtGATA18
Descriptor: GATA transcription factor 18, Sequence-variable mosaic (SVM) signal sequence domain-containing protein, ZINC ION
Authors:Dong, C, Yan, X, Yuan, X.
Deposit date:2023-04-19
Release date:2024-02-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Molecular basis of SAP05-mediated ubiquitin-independent proteasomal degradation of transcription factors
Nat Commun, 15, 2024
8J4A
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BU of 8j4a by Molmil
Crystal structure of OY phytoplasma SAP05 in complex with AtRPN10
Descriptor: 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein
Authors:Dong, C, Yan, X, Yuan, X.
Deposit date:2023-04-19
Release date:2024-02-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Molecular basis of SAP05-mediated ubiquitin-independent proteasomal degradation of transcription factors
Nat Commun, 15, 2024
8J49
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BU of 8j49 by Molmil
Crystal structure of OY phytoplasma SAP05 in complex with AtSPL5
Descriptor: Sequence-variable mosaic (SVM) signal sequence domain-containing protein, Squamosa promoter-binding-like protein 5, ZINC ION
Authors:Dong, C, Yan, X, Yuan, X.
Deposit date:2023-04-19
Release date:2024-02-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Molecular basis of SAP05-mediated ubiquitin-independent proteasomal degradation of transcription factors
Nat Commun, 15, 2024
8J4B
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BU of 8j4b by Molmil
Crystal structure of OY phytoplasma SAP05 in complex with AtSPL13
Descriptor: Sequence-variable mosaic (SVM) signal sequence domain-containing protein, Squamosa promoter-binding-like protein 13A, ZINC ION
Authors:Dong, C, Yan, X, Yuan, X.
Deposit date:2023-04-19
Release date:2024-02-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis of SAP05-mediated ubiquitin-independent proteasomal degradation of transcription factors
Nat Commun, 15, 2024
4N9F
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BU of 4n9f by Molmil
Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex
Descriptor: Core-binding factor subunit beta, Cullin-5, Transcription elongation factor B polypeptide 1, ...
Authors:Guo, Y.Y, Dong, L.Y, Huang, Z.W.
Deposit date:2013-10-21
Release date:2014-01-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for hijacking CBF-b and CUL5 E3 ligase complex by HIV-1 Vif
Nature, 505, 2014
7KBH
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BU of 7kbh by Molmil
Structure of Human HDAC2 in complex with a 2-substituted benzamide inhibitor (compound 16)
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Histone deacetylase 2, ...
Authors:Klein, D.J, Liu, J.
Deposit date:2020-10-02
Release date:2020-12-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group.
Acs Med.Chem.Lett., 11, 2020
7KBG
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BU of 7kbg by Molmil
Structure of Human HDAC2 in complex with a 2-substituted benzamide inhibitor (compound 20)
Descriptor: 2,5-dichloro-1H-benzimidazole, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Klein, D.J, Liu, J.
Deposit date:2020-10-02
Release date:2020-12-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group.
Acs Med.Chem.Lett., 11, 2020
4NX2
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BU of 4nx2 by Molmil
Crystal structure of DCYRS complexed with DCY
Descriptor: 3,5-dichloro-L-tyrosine, Tyrosine--tRNA ligase
Authors:Wang, J, Gong, W, Li, J, Gao, F, Li, H.
Deposit date:2013-12-08
Release date:2014-09-24
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4NXE
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BU of 4nxe by Molmil
Crystal structure of iLOV-I486(2LT) at pH 6.5
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Wang, J, Liu, X, Li, J.
Deposit date:2013-12-09
Release date:2014-09-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4NXF
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BU of 4nxf by Molmil
Crystal structure of iLOV-I486(2LT) at pH 8.0
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Wang, J, Liu, X, Li, J.
Deposit date:2013-12-09
Release date:2014-09-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.766 Å)
Cite:Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4NXG
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BU of 4nxg by Molmil
Crystal structure of iLOV-I486z(2LT) at pH 9.0
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Wang, J, Liu, X, Li, J.
Deposit date:2013-12-09
Release date:2014-09-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4NXB
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BU of 4nxb by Molmil
Crystal structure of iLOV-I486(2LT) at pH 7.0
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Wang, J, Li, J, Liu, X.
Deposit date:2013-12-09
Release date:2014-09-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.561 Å)
Cite:Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4X8X
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BU of 4x8x by Molmil
Crystal structure of Dscam1 isoform 1.9, N-terminal four Ig domains
Descriptor: Down Syndrome cell adhesion molecule isoform 1.9, GLYCEROL, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, Q.
Deposit date:2014-12-11
Release date:2015-12-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4X9H
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BU of 4x9h by Molmil
Crystal structure of Dscam1 isoform 8.4, N-terminal four Ig domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule, isoform AP, ...
Authors:Chen, Q.
Deposit date:2014-12-11
Release date:2015-12-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4XNM
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BU of 4xnm by Molmil
Antibody Influenza H5 Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H5.3 FAB Heavy Chain, H5.3 FAB Light Chain, ...
Authors:Winarski, K.L, Spiler, B.W.
Deposit date:2015-01-15
Release date:2015-07-15
Last modified:2022-03-30
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites.
Proc.Natl.Acad.Sci.USA, 112, 2015

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