5HFM
| Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail | Descriptor: | Envelope glycoprotein gp160,gp41 CHR region, TRIS(HYDROXYETHYL)AMINOMETHANE | Authors: | Zhu, Y, Ye, S, Zhang, R. | Deposit date: | 2016-01-07 | Release date: | 2017-01-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations Sci Rep, 6, 2016
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5HFL
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3NAF
| Structure of the Intracellular Gating Ring from the Human High-conductance Ca2+ gated K+ Channel (BK Channel) | Descriptor: | Calcium-activated potassium channel subunit alpha-1,Calcium-activated potassium channel subunit alpha-1,Calcium-activated potassium channel subunit alpha-1 | Authors: | Wu, Y, Yang, Y, Ye, S, Jiang, Y. | Deposit date: | 2010-06-01 | Release date: | 2010-06-30 | Last modified: | 2017-06-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel. Nature, 466, 2010
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3R65
| MthK channel pore E92Q mutant | Descriptor: | Calcium-gated potassium channel mthK, POTASSIUM ION | Authors: | Shi, N, Zeng, W, Ye, S, Li, Y, Jiang, Y. | Deposit date: | 2011-03-21 | Release date: | 2012-02-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crucial points within the pore as determinants of K+ channel conductance and gating J.Mol.Biol., 411, 2011
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6A30
| Crystal Structure of Munc13-1 MUN Domain and Synaptobrevin-2 Juxtamembrane Linker Region | Descriptor: | Protein unc-13 homolog A, Synaptobrevin-2 juxtamembrane linker peptide | Authors: | Wang, S, Li, Y, Gong, J.H, Ye, S, Yang, X.F, Zhang, R.G, Ma, C. | Deposit date: | 2018-06-14 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.793 Å) | Cite: | Munc18 and Munc13 serve as a functional template to orchestrate neuronal SNARE complex assembly. Nat Commun, 10, 2019
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6A96
| Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-5,Gamma-aminobutyric acid receptor subunit alpha-5, ... | Authors: | Liu, S, Xu, L, Guan, F, Liu, Y.T, Cui, Y, Zhang, Q, Bi, G.Q, Zhou, Z.H, Zhang, X, Ye, S. | Deposit date: | 2018-07-11 | Release date: | 2018-10-03 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Cryo-EM structure of the human alpha 5 beta 3 GABAAreceptor. Cell Res., 28, 2018
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6A0A
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6A0C
| Structure of a triple-helix region of human collagen type III | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, collagen type III peptide | Authors: | Yang, X, Zhu, Y, Ye, S, Zhang, R. | Deposit date: | 2018-06-05 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity. Biochem. Biophys. Res. Commun., 508, 2019
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4KWE
| GDP-bound, double-stranded, curved FtsZ protofilament structure | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | Authors: | Li, Y, Hsin, J, Zhao, L, Cheng, Y, Shang, W, Huang, K.C, Wang, H.W, Ye, S. | Deposit date: | 2013-05-23 | Release date: | 2013-07-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | FtsZ protofilaments use a hinge-opening mechanism for constrictive force generation Science, 341, 2013
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4F7G
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4F7H
| The crystal structure of kindlin-2 pleckstrin homology domain in free form | Descriptor: | Fermitin family homolog 2, S,R MESO-TARTARIC ACID | Authors: | Liu, Y, Zhu, Y, Qin, J, Ye, S, Zhang, R. | Deposit date: | 2012-05-16 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation. Protein Cell, 3, 2012
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4FNV
| Crystal Structure of Heparinase III | Descriptor: | Heparinase III protein, heparitin sulfate lyase | Authors: | Dong, W, Ye, S. | Deposit date: | 2012-06-20 | Release date: | 2012-11-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis of heparan sulfate-specific degradation by heparinase III. Protein Cell, 3, 2012
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4GX2
| GsuK channel bound to NAD | Descriptor: | CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
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4GX1
| Crystal structure of the GsuK bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
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1J04
| Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro | Descriptor: | (AMINOOXY)ACETIC ACID, GLYCEROL, alanine--glyoxylate aminotransferase | Authors: | Zhang, X, Djordjevic, S, Bartlam, M, Ye, S, Rao, Z, Danpure, C.J. | Deposit date: | 2002-10-30 | Release date: | 2003-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting. Acta Crystallogr.,Sect.F, 66, 2010
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4H5Y
| High-resolution crystal structure of Legionella pneumophila LidA (60-594) | Descriptor: | LidA protein, substrate of the Dot/Icm system | Authors: | An, X, Ye, S, Liu, Y, Zheng, X, Zhang, R. | Deposit date: | 2012-09-19 | Release date: | 2013-09-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of LidA, a translocated substrate of the Legionella pneumophila type IV secretion system. Protein Cell, 4, 2013
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4N5Q
| Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Shi, D.J, Ye, S, Cao, X, Wang, K.W, Zhang, R. | Deposit date: | 2013-10-10 | Release date: | 2014-01-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.946 Å) | Cite: | Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 reveals unique conformation of finger 3 loop critical for channel function Protein Cell, 4, 2013
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4GX0
| Crystal structure of the GsuK L97D mutant | Descriptor: | CALCIUM ION, PHOSPHATE ION, POTASSIUM ION, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
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4GX5
| GsuK Channel | Descriptor: | CALCIUM ION, POTASSIUM ION, TrkA domain protein, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
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4GVL
| Crystal Structure of the GsuK RCK domain | Descriptor: | ADENOSINE MONOPHOSPHATE, CALCIUM ION, TrkA domain protein, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-08-30 | Release date: | 2012-12-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
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4QE7
| Open MthK pore structure soaked in 10 mM Ba2+/100 mM Na+ | Descriptor: | BARIUM ION, Calcium-gated potassium channel MthK | Authors: | Guo, R, Zeng, W, Cui, H, Chen, L, Ye, S. | Deposit date: | 2014-05-15 | Release date: | 2014-07-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Ionic interactions of Ba2+ blockades in the MthK K+ channel J.Gen.Physiol., 144, 2014
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7D99
| human potassium-chloride co-transporter KCC4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J. | Deposit date: | 2020-10-12 | Release date: | 2020-12-30 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures and an activation mechanism of human potassium-chloride cotransporters. Sci Adv, 6, 2020
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7D90
| human potassium-chloride co-transporter KCC3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, potassium-chloride cotransporter 3 | Authors: | Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J. | Deposit date: | 2020-10-12 | Release date: | 2020-12-30 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures and an activation mechanism of human potassium-chloride cotransporters. Sci Adv, 6, 2020
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7D8Z
| human potassium-chloride co-transporter KCC2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, potassium-chloride cotransporter 2 | Authors: | Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J. | Deposit date: | 2020-10-11 | Release date: | 2020-12-30 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures and an activation mechanism of human potassium-chloride cotransporters. Sci Adv, 6, 2020
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6KKU
| human KCC1 structure determined in NaCl and GDN | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | Deposit date: | 2019-07-27 | Release date: | 2019-10-23 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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