4RAX
| A regulatory domain of an ion channel | 分子名称: | Piezo-type mechanosensitive ion channel component 1 | 著者 | Ge, J, Yang, M. | 登録日 | 2014-09-11 | 公開日 | 2015-09-23 | 最終更新日 | 2018-04-18 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Architecture of the mammalian mechanosensitive Piezo1 channel. Nature, 527, 2015
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4R3M
| Crystal structure of Human Hsp90 with JR9 | 分子名称: | Heat shock protein HSP 90-alpha, N~3~-benzyl-2-[(6-bromo-1,3-benzodioxol-5-yl)methyl]imidazo[1,2-a]pyrazine-3,8-diamine | 著者 | Li, J, Yang, M, Ren, J, Xiong, B, He, J. | 登録日 | 2014-08-16 | 公開日 | 2014-11-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienayme reaction and their Hsp90 inhibitory activity. Org.Biomol.Chem., 13, 2015
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3FXV
| Identification of an N-oxide pyridine GW4064 analogue as a potent FXR agonist | 分子名称: | 12-meric peptide from Nuclear receptor coactivator 1, 6-(4-{[3-(3,5-dichloropyridin-4-yl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-2-methylphenyl)-1-methyl-1H-indole-3-carbox ylic acid, NR1H4 protein | 著者 | Feng, S, Yang, M, He, Y, Chen, L, Zhang, Z, Wang, Z, Hong, D, Richter, H, Benson, G.M, Bleicher, K, Grether, U, Martin, R, Plancher, J.-M, Kuhn, B, Rudolph, M.G. | 登録日 | 2009-01-21 | 公開日 | 2009-04-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist Bioorg.Med.Chem.Lett., 19, 2009
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2C1X
| Structure and activity of a flavonoid 3-O glucosyltransferase reveals the basis for plant natural product modification | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, UDP-GLUCOSE FLAVONOID 3-O GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | 著者 | Offen, W, Martinez-Fleites, C, Kiat-Lim, E, Yang, M, Davis, B.G, Tarling, C.A, Ford, C.M, Bowles, D.J, Davies, G.J. | 登録日 | 2005-09-22 | 公開日 | 2006-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification. Embo J., 25, 2006
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2BO8
| DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | 分子名称: | CHLORIDE ION, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER, ... | 著者 | Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. | 登録日 | 2005-04-08 | 公開日 | 2005-06-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural dissection and high-throughput screening of mannosylglycerate synthase. Nat. Struct. Mol. Biol., 12, 2005
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2BO6
| DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | 分子名称: | (2R)-2,3-DIHYDROXYPROPANOIC ACID, MANGANESE (II) ION, MANNOSYLGLYCERATE SYNTHASE | 著者 | Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. | 登録日 | 2005-04-08 | 公開日 | 2005-06-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural Dissection and High-Throughput Screening of Mannosylglyceerate Synthase Nat.Struct.Mol.Biol., 12, 2005
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2BO7
| DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | 分子名称: | COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE, MANNOSYLGLYCERATE SYNTHASE | 著者 | Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. | 登録日 | 2005-04-08 | 公開日 | 2005-06-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural dissection and high-throughput screening of mannosylglycerate synthase. Nat. Struct. Mol. Biol., 12, 2005
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2BO4
| Dissection of mannosylglycerate synthase: an archetypal mannosyltransferase | 分子名称: | CITRATE ANION, MANNOSYLGLYCERATE SYNTHASE | 著者 | Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. | 登録日 | 2005-04-07 | 公開日 | 2005-06-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Dissection and High-Throughput Screening of Mannosylglyceerate Synthase Nat.Struct.Mol.Biol., 12, 2005
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2C1Z
| Structure and activity of a flavonoid 3-O glucosyltransferase reveals the basis for plant natural product modification | 分子名称: | 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, UDP-GLUCOSE FLAVONOID 3-O GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE | 著者 | Offen, W, Martinez-Fleites, C, Kiat-Lim, E, Yang, M, Davis, B.G, Tarling, C.A, Ford, C.M, Bowles, D.J, Davies, G.J. | 登録日 | 2005-09-22 | 公開日 | 2006-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification. Embo J., 25, 2006
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2C9Z
| Structure and activity of a flavonoid 3-0 glucosyltransferase reveals the basis for plant natural product modification | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, UDP GLUCOSE:FLAVONOID 3-O-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | 著者 | Offen, W, Martinez-Fleites, C, Kiat-Lim, E, Yang, M, Davis, B.G, Tarling, C.A, Ford, C.M, Bowles, D.J, Davies, G.J. | 登録日 | 2005-12-15 | 公開日 | 2006-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification. Embo J., 25, 2006
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5YEI
| Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase | 分子名称: | Aspartokinase, GLYCEROL, LYSINE, ... | 著者 | Li, C, Yang, M, Liu, L, Peng, C, Li, T, He, L, Song, Y, Zhu, Y, Bao, R. | 登録日 | 2017-09-17 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase. Biochem.J., 475, 2018
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2Y4J
| MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH LACTATE | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, LACTIC ACID, MANNOSYLGLYCERATE SYNTHASE, ... | 著者 | Nielsen, M.M, Suits, M.D.L, Yang, M, Barry, C.S, Martinez-Fleites, C, Tailford, L.E, Flint, J.E, Davis, B.G, Davies, G.J, Gilbert, H.J. | 登録日 | 2011-01-07 | 公開日 | 2011-02-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase. J.Biol.Chem., 286, 2011
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2Y4L
| MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH Manganese and GDP | 分子名称: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MALONATE ION, ... | 著者 | Nielsen, M.M, Suits, M.D.L, Yang, M, Barry, C.S, Martinez-Fleites, C, Tailford, L.E, Flint, J.E, Davis, B.G, Davies, G.J, Gilbert, H.J. | 登録日 | 2011-01-07 | 公開日 | 2011-02-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase. J.Biol.Chem., 286, 2011
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2Y4K
| MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH MG-GDP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, FORMIC ACID, ... | 著者 | Nielsen, M.M, Suits, M.D.L, Yang, M, Barry, C.S, Martinez-Fleites, C, Tailford, L.E, Flint, J.E, Davis, B.G, Davies, G.J, Gilbert, H.J. | 登録日 | 2011-01-07 | 公開日 | 2011-02-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase. J.Biol.Chem., 286, 2011
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2Y4M
| MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH GDP-Mannose | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), ... | 著者 | Nielsen, M.M, Suits, M.D.L, Yang, M, Barry, C.S, Martinez-Fleites, C, Tailford, L.E, Flint, J.E, Davis, B.G, Davies, G.J, Gilbert, H.J. | 登録日 | 2011-01-07 | 公開日 | 2011-02-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase. J.Biol.Chem., 286, 2011
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3JA8
| Cryo-EM structure of the MCM2-7 double hexamer | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ... | 著者 | Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N. | 登録日 | 2015-05-09 | 公開日 | 2015-08-05 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the eukaryotic MCM complex at 3.8 angstrom Nature, 524, 2015
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3MGT
| Crystal structure of a H5-specific CTL epitope variant derived from H5N1 influenza virus in complex with HLA-A*0201 | 分子名称: | 10-meric peptide from Hemagglutinin, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Sun, Y, Liu, J, Yang, M, Gao, F, Zhou, J, Kitamura, Y. | 登録日 | 2010-04-07 | 公開日 | 2010-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | 主引用文献 | Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses J.Gen.Virol., 91, 2010
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3MGO
| Crystal structure of a H5-specific CTL epitope derived from H5N1 influenza virus in complex with HLA-A*0201 | 分子名称: | 10-meric peptide from Hemagglutinin, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Sun, Y, Liu, J, Yang, M, Gao, F, Zhou, J, Kitamura, Y. | 登録日 | 2010-04-07 | 公開日 | 2010-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | 主引用文献 | Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses J.Gen.Virol., 91, 2010
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4YMW
| Crystal structure of an amino acid ABC transporter with histidines | 分子名称: | ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ... | 著者 | Ge, J, Yu, J, Yang, M. | 登録日 | 2015-03-07 | 公開日 | 2015-04-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | 主引用文献 | Structural basis for substrate specificity of an amino acid ABC transporter Proc.Natl.Acad.Sci.USA, 112, 2015
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4YMT
| Crystal structure of an amino acid ABC transporter complex with arginines | 分子名称: | ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ... | 著者 | Ge, J, Yu, J, Yang, M. | 登録日 | 2015-03-07 | 公開日 | 2015-04-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.599 Å) | 主引用文献 | Structural basis for substrate specificity of an amino acid ABC transporter Proc.Natl.Acad.Sci.USA, 112, 2015
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3UDC
| Crystal structure of a membrane protein | 分子名称: | Small-conductance mechanosensitive channel, C-terminal peptide from Small-conductance mechanosensitive channel | 著者 | Li, W, Ge, J, Yang, M. | 登録日 | 2011-10-28 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.355 Å) | 主引用文献 | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance Proc.Natl.Acad.Sci.USA, 109, 2012
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5BOA
| Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb bound to the disaccharide receptor Gb2 | 分子名称: | Translation initiation factor 2 (IF-2 GTPase), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose | 著者 | Zhang, C, Yu, Y, Yang, M, Jiang, Y. | 登録日 | 2015-05-27 | 公開日 | 2016-05-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.708 Å) | 主引用文献 | Structural basis of the interaction between the meningitis pathogen Streptococcus suis adhesin Fhb and its human receptor. Febs Lett., 590, 2016
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4G6H
| Crystal structure of NDH with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | 著者 | Li, W, Feng, Y, Ge, J, Yang, M. | 登録日 | 2012-07-19 | 公開日 | 2012-10-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.262 Å) | 主引用文献 | Structural insight into the type-II mitochondrial NADH dehydrogenases. Nature, 491, 2012
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4FWI
| Crystal structure of the nucleotide-binding domain of a dipeptide ABC transporter | 分子名称: | ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Li, X, Ge, J, Yang, M, Wang, N. | 登録日 | 2012-07-01 | 公開日 | 2013-01-30 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.892 Å) | 主引用文献 | Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain Acta Crystallogr.,Sect.D, 69, 2013
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4G6G
| Crystal structure of NDH with TRT | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FRAGMENT OF TRITON X-100, MAGNESIUM ION, ... | 著者 | Li, W, Feng, Y, Ge, J, Yang, M. | 登録日 | 2012-07-19 | 公開日 | 2012-10-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural insight into the type-II mitochondrial NADH dehydrogenases. Nature, 491, 2012
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