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7V7M
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BU of 7v7m by Molmil
crystal structure of SARS-CoV-2 3CL protease
分子名称: 3C-like proteinase
著者Yi, Y, Zhang, M, Ye, M.
登録日2021-08-21
公開日2022-06-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Schaftoside inhibits 3CL pro and PL pro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19.
Acta Pharm Sin B, 12, 2022
7X5C
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BU of 7x5c by Molmil
Solution structure of Tetrahymena p75OB1-p50PBM
分子名称: Telomerase associated protein p50PBM, Telomerase-associated protein p75OB1
著者Wu, B, Tang, T, Xue, H.J, Wu, J, Lei, M.
登録日2022-03-04
公開日2022-10-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Association of the CST complex and p50 in Tetrahymena is crucial for telomere maintenance
Structure, 2022
7EA8
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BU of 7ea8 by Molmil
Human SETD2 bound to a nucleosome containing oncohistone mutations
分子名称: 601-DNA, Histone H2A type 1-D, Histone H2B type 2-E, ...
著者Jing, H, Liu, Y.
登録日2021-03-06
公開日2021-07-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations.
Cell Discov, 7, 2021
7EA5
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BU of 7ea5 by Molmil
Yeast Set2 bound to a nucleosome containing oncohistone mutations
分子名称: 601-DNA, Histone H2A, Histone H2B, ...
著者Jing, H, Liu, Y.
登録日2021-03-06
公開日2021-07-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations.
Cell Discov, 7, 2021
7VU5
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BU of 7vu5 by Molmil
Structure of the transmembrane domain of the CD28 dimer
分子名称: T-cell-specific surface glycoprotein CD28
著者Wu, H, Cao, R, Wen, M, Ouyang, B.
登録日2021-11-01
公開日2022-03-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of a dimerization interface in the CD28 transmembrane domain.
Structure, 30, 2022
6L8R
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BU of 6l8r by Molmil
membrane-bound PD-L1-CD
分子名称: Programmed cell death 1 ligand 1
著者Maorong, W, Cao, Y, Bin, W, Bo, O.
登録日2019-11-07
公開日2020-11-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain.
Nat Commun, 12, 2021
6LQZ
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BU of 6lqz by Molmil
Solution structure of Taf14ET-Sth1EBMC
分子名称: Nuclear protein STH1/NPS1, Transcription initiation factor TFIID subunit 14
著者Wu, B, Chen, G, Chen, Y.
登録日2020-01-15
公開日2020-08-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Taf14 recognizes a common motif in transcriptional machineries and facilitates their clustering by phase separation.
Nat Commun, 11, 2020
8GP7
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BU of 8gp7 by Molmil
Structure of Trioxacarcin A covalently bound to RET G4-DNA
分子名称: DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), Trioxacarcin A, bound form
著者Yin, S, Cao, C.
登録日2022-08-25
公開日2023-09-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Trioxacarcin A Interactions with G-Quadruplex DNA Reveal Its Potential New Targets as an Anticancer Agent.
J.Med.Chem., 66, 2023
7XH3
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BU of 7xh3 by Molmil
Dimeric G-quadruplex DNA Formed in the Proximal Promoter of VEGFR-2
分子名称: DNA (5'-D(*CP*CP*GP*GP*GP*TP*AP*CP*CP*CP*GP*G)-3')
著者Zhang, Y, Lan, W, Wang, C, Cao, C.
登録日2022-04-07
公開日2023-02-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dimeric G-quadruplex DNA Structure in the Proximal Promoter of VEGFR-2 Reveals a New Drug Target to Inhibit Tumor Angiogenesis.
Chin.J.Chem., 40, 2022
7XFV
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BU of 7xfv by Molmil
Dimeric G-quadruplex DNA Formed in the Proximal Promoter of VEGFR-2
分子名称: DNA (5'-D(*AP*TP*GP*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3')
著者Zhang, Y, Lan, W, Wang, C, Cao, C.
登録日2022-04-02
公開日2023-03-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dimeric G-quadruplex DNA Structure in the Proximal Promoter of VEGFR-2 Reveals a New Drug Target to Inhibit Tumor Angiogenesis.
Chin.J.Chem., 40, 2023
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