3FG2
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3QAK
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![BU of 3qak by Molmil](/molmil-images/mine/3qak) | Agonist bound structure of the human adenosine A2a receptor | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl)carbamoylamino]ethyl]purine-2-carboxamide, Adenosine receptor A2a,lysozyme chimera | Authors: | Xu, F, Wu, H, Katritch, V, Han, G.W, Cherezov, V, Stevens, R, GPCR Network (GPCR) | Deposit date: | 2011-01-11 | Release date: | 2011-03-09 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structure of an agonist-bound human A2A adenosine receptor. Science, 332, 2011
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2EXU
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![BU of 2exu by Molmil](/molmil-images/mine/2exu) | Crystal Structure of Saccharomyces cerevisiae transcription elongation factors Spt4-Spt5NGN domain | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ETHANOL, Transcription initiation protein SPT4/SPT5, ... | Authors: | Xu, F, Guo, M, Fang, P, Teng, M, Niu, L. | Deposit date: | 2005-11-08 | Release date: | 2006-11-08 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Crystal Structure of Saccharomyces cerevisiae transcription elongation factors Spt4-Spt5NGN domain To be published
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2FRZ
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2GR6
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7DRQ
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![BU of 7drq by Molmil](/molmil-images/mine/7drq) | Crystal structure of polysaccharide lyase Uly1 | Descriptor: | CALCIUM ION, Uly1 | Authors: | Chen, X.L, Cao, H.Y, Xu, F, Dong, F. | Deposit date: | 2020-12-29 | Release date: | 2021-03-31 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Mechanistic Insights into Substrate Recognition and Catalysis of a New Ulvan Lyase of Polysaccharide Lyase Family 24. Appl.Environ.Microbiol., 87, 2021
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7CZH
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![BU of 7czh by Molmil](/molmil-images/mine/7czh) | PL24 ulvan lyase-Uly1 | Descriptor: | CALCIUM ION, GLYCEROL, Uly1 | Authors: | Zhang, Y.Z, Chen, X.L, Dong, F, Xu, F. | Deposit date: | 2020-09-08 | Release date: | 2021-04-07 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | Mechanistic Insights into Substrate Recognition and Catalysis of a New Ulvan Lyase of Polysaccharide Lyase Family 24. Appl.Environ.Microbiol., 87, 2021
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7SUS
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![BU of 7sus by Molmil](/molmil-images/mine/7sus) | Crystal structure of Apelin receptor in complex with small molecule | Descriptor: | (1R,2S)-N-[4-(2,6-dimethoxyphenyl)-5-(6-methylpyridin-2-yl)-1,2,4-triazol-3-yl]-1-(5-methylpyrimidin-2-yl)-1-oxidanyl-propane-2-sulfonamide, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Apelin receptor, ... | Authors: | Xu, F, Yue, Y, Liu, L.E, Han, G.W, Hanson, M. | Deposit date: | 2021-11-18 | Release date: | 2022-07-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insight into apelin receptor-G protein stoichiometry. Nat.Struct.Mol.Biol., 29, 2022
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4EJR
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![BU of 4ejr by Molmil](/molmil-images/mine/4ejr) | Crystal structure of major capsid protein S domain from rabbit hemorrhagic disease virus | Descriptor: | Major capsid protein VP60 | Authors: | Xu, F, Ma, J, Zhang, K, Wang, X, Sun, F. | Deposit date: | 2012-04-07 | Release date: | 2013-01-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. Plos Pathog., 9, 2013
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5GKQ
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![BU of 5gkq by Molmil](/molmil-images/mine/5gkq) | Structure of PL6 family alginate lyase AlyGC mutant-R241A | Descriptor: | AlyGC mutant - R241A, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | Authors: | Zhang, Y.Z, Wang, P, Xu, F. | Deposit date: | 2016-07-05 | Release date: | 2017-02-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.565 Å) | Cite: | Novel Molecular Insights into the Catalytic Mechanism of Marine Bacterial Alginate Lyase AlyGC from Polysaccharide Lyase Family 6 J. Biol. Chem., 292, 2017
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5GKD
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![BU of 5gkd by Molmil](/molmil-images/mine/5gkd) | Structure of PL6 family alginate lyase AlyGC | Descriptor: | AlyGC, CALCIUM ION, CARBONATE ION, ... | Authors: | Zhang, Y.Z, Wang, P, Xu, F. | Deposit date: | 2016-07-04 | Release date: | 2017-02-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | Novel Molecular Insights into the Catalytic Mechanism of Marine Bacterial Alginate Lyase AlyGC from Polysaccharide Lyase Family 6 J. Biol. Chem., 292, 2017
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8JHB
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![BU of 8jhb by Molmil](/molmil-images/mine/8jhb) | FZD6 Gs complex | Descriptor: | Frizzled-6, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, F, Zhang, Z. | Deposit date: | 2023-05-23 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways. Cell Discov, 10, 2024
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8JHI
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![BU of 8jhi by Molmil](/molmil-images/mine/8jhi) | FZD3-Gs complex | Descriptor: | Frizzled-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, F, Zhang, Z. | Deposit date: | 2023-05-23 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways. Cell Discov, 10, 2024
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8JH7
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![BU of 8jh7 by Molmil](/molmil-images/mine/8jh7) | FZD6 in inactive state | Descriptor: | Frizzled-6,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ... | Authors: | Xu, F, Zhang, Z. | Deposit date: | 2023-05-22 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways. Cell Discov, 10, 2024
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8JHC
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![BU of 8jhc by Molmil](/molmil-images/mine/8jhc) | FZD3 in inactive state | Descriptor: | Frizzled-3,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ... | Authors: | Xu, F, Zhang, Z. | Deposit date: | 2023-05-23 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways. Cell Discov, 10, 2024
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7C8G
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![BU of 7c8g by Molmil](/molmil-images/mine/7c8g) | Structure of alginate lyase AlyC3 | Descriptor: | Alginate lyase AlyC3, GLYCEROL, SUCCINIC ACID | Authors: | Zhang, Y.Z, Xu, F, Chen, X.L, Wang, P. | Deposit date: | 2020-05-30 | Release date: | 2020-10-07 | Last modified: | 2020-12-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the arctic. J.Biol.Chem., 295, 2020
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7C8F
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![BU of 7c8f by Molmil](/molmil-images/mine/7c8f) | Structure of alginate lyase AlyC3 in complex with dimannuronate(2M) | Descriptor: | H127A/Y244A mutant of alginate lyase AlyC3 in complex with dimannuronate, MALONATE ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | Authors: | Zhang, Y.Z, Xu, F, Chen, X.L, Wang, P. | Deposit date: | 2020-05-30 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.461 Å) | Cite: | Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the arctic. J.Biol.Chem., 295, 2020
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2GQX
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![BU of 2gqx by Molmil](/molmil-images/mine/2gqx) | Crystal structure of cytochrome p450cam mutant (f87w/y96f/l244a/v247l/c334a) with pentachlorobenzene | Descriptor: | 1,2,3,4,5-PENTACHLOROBENZENE, Cytochrome P450-cam, POTASSIUM ION, ... | Authors: | Rao, Z, Wong, L.L, Xu, F, Bell, S.G. | Deposit date: | 2006-04-22 | Release date: | 2007-04-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-activity correlations in pentachlorobenzene oxidation by engineered cytochrome P450cam Protein Eng.Des.Sel., 20, 2007
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7VNQ
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![BU of 7vnq by Molmil](/molmil-images/mine/7vnq) | Structure of human KCNQ4-ML213 complex in nanodisc | Descriptor: | (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid, Calmodulin-3, POTASSIUM ION, ... | Authors: | Xu, F, Zheng, Y. | Deposit date: | 2021-10-11 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel. Neuron, 110, 2022
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7VNR
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![BU of 7vnr by Molmil](/molmil-images/mine/7vnr) | Structure of human KCNQ4-ML213 complex in digitonin | Descriptor: | (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid, Calmodulin-3, POTASSIUM ION, ... | Authors: | Xu, F, Zheng, Y. | Deposit date: | 2021-10-11 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel. Neuron, 110, 2022
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7VNP
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![BU of 7vnp by Molmil](/molmil-images/mine/7vnp) | Structure of human KCNQ4-ML213 complex with PIP2 | Descriptor: | (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid, Calmodulin-3, POTASSIUM ION, ... | Authors: | Xu, F, Zheng, Y. | Deposit date: | 2021-10-11 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel. Neuron, 110, 2022
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7W0N
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![BU of 7w0n by Molmil](/molmil-images/mine/7w0n) | Cryo-EM structure of a dimeric GPCR-Gi complex with peptide | Descriptor: | Apelin receptor early endogenous ligand, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, F, Yue, Y, Wu, L.J, Liu, L.E, Hanson, M. | Deposit date: | 2021-11-18 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (4.21 Å) | Cite: | Structural insight into apelin receptor-G protein stoichiometry. Nat.Struct.Mol.Biol., 29, 2022
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7W0O
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![BU of 7w0o by Molmil](/molmil-images/mine/7w0o) | Cryo-EM structure of a monomeric GPCR-Gi complex with peptide | Descriptor: | Apelin receptor early endogenous ligand, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, F, Yue, Y, Liu, L.E, Wu, L.J, Hanson, M. | Deposit date: | 2021-11-18 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Structural insight into apelin receptor-G protein stoichiometry. Nat.Struct.Mol.Biol., 29, 2022
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7W0M
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![BU of 7w0m by Molmil](/molmil-images/mine/7w0m) | Cryo-EM structure of a monomeric GPCR-Gi complex with small molecule | Descriptor: | (1R,2S)-N-[4-(2,6-dimethoxyphenyl)-5-(6-methylpyridin-2-yl)-1,2,4-triazol-3-yl]-1-(5-methylpyrimidin-2-yl)-1-oxidanyl-propane-2-sulfonamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, F, Yue, Y, Liu, L.E, Wu, L.J, Hanson, M. | Deposit date: | 2021-11-18 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Structural insight into apelin receptor-G protein stoichiometry. Nat.Struct.Mol.Biol., 29, 2022
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7W0P
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![BU of 7w0p by Molmil](/molmil-images/mine/7w0p) | Cryo-EM structure of a GPCR-Gi complex with peptide | Descriptor: | Apelin receptor early endogenous ligand, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, F, Yue, Y, Liu, L.E, Wu, L.J, Hanson, M. | Deposit date: | 2021-11-18 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structural insight into apelin receptor-G protein stoichiometry. Nat.Struct.Mol.Biol., 29, 2022
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