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7CJY
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BU of 7cjy by Molmil
Drimenol synthase from Persicaria hydropiper
Descriptor: (-)-drimenol synthase
Authors:Xiao, W, Zhou, H, Zhou, M.T, Liu, L, Xiang, Z.
Deposit date:2020-07-14
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Biochemical Studies of Drimenol Synthase from Persicaria hydropiper
To Be Published
6DKD
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BU of 6dkd by Molmil
Yeast Ddi2 Cyanamide Hydratase
Descriptor: DNA damage-inducible protein, SULFATE ION, ZINC ION
Authors:Moore, S.A, Xiao, W, Li, J.
Deposit date:2018-05-29
Release date:2019-05-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Ddi2, a highly inducible detoxifying metalloenzyme fromSaccharomyces cerevisiae.
J.Biol.Chem., 294, 2019
6DKC
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BU of 6dkc by Molmil
Yeast Ddi2 Cyanamide Hydratase, T157V mutant, apo structure
Descriptor: DNA damage-inducible protein, SULFATE ION, ZINC ION
Authors:Moore, S.A, Xiao, W, Li, J.
Deposit date:2018-05-29
Release date:2019-05-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of Ddi2, a highly inducible detoxifying metalloenzyme fromSaccharomyces cerevisiae.
J.Biol.Chem., 294, 2019
6DKA
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BU of 6dka by Molmil
Yeast Ddi2 Cyanamide Hydratase
Descriptor: CYANAMIDE, DNA damage-inducible protein, SULFATE ION, ...
Authors:Moore, S.A, Xiao, W, Li, J.
Deposit date:2018-05-29
Release date:2019-05-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structure of Ddi2, a highly inducible detoxifying metalloenzyme fromSaccharomyces cerevisiae.
J.Biol.Chem., 294, 2019
6DK9
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BU of 6dk9 by Molmil
Yeast Ddi2 Cyanamide Hydratase
Descriptor: DNA damage-inducible protein, SULFATE ION, ZINC ION
Authors:Moore, S.A, Xiao, W, Li, J.
Deposit date:2018-05-29
Release date:2019-05-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Ddi2, a highly inducible detoxifying metalloenzyme fromSaccharomyces cerevisiae.
J.Biol.Chem., 294, 2019
1J74
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BU of 1j74 by Molmil
Crystal Structure of Mms2
Descriptor: MMS2
Authors:Moraes, T.F, Edwards, R.A, McKenna, S, Pastushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
Deposit date:2001-05-15
Release date:2001-08-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
1J7D
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BU of 1j7d by Molmil
Crystal Structure of hMms2-hUbc13
Descriptor: MMS2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA
Authors:Moraes, T.F, Edwards, R.A, McKenna, S, Pashushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
Deposit date:2001-05-16
Release date:2001-08-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
1ZGU
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BU of 1zgu by Molmil
Solution structure of the human Mms2-Ubiquitin complex
Descriptor: Ubiquitin, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Lewis, M.J, Saltibus, L.F, Hau, D.D, Xiao, W, Spyracopoulos, L.
Deposit date:2005-04-22
Release date:2006-04-04
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2.
J.Biomol.Nmr, 34, 2006
2JMD
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BU of 2jmd by Molmil
Solution Structure of the Ring Domain of Human TRAF6
Descriptor: TNF receptor-associated factor 6, ZINC ION
Authors:Mercier, P, Lewis, M.J, Hau, D.D, Saltibus, L.F, Xiao, W, Spyracopoulos, L.
Deposit date:2006-11-02
Release date:2007-04-10
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Structure, interactions, and dynamics of the RING domain from human TRAF6
Protein Sci., 16, 2007
2HLW
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BU of 2hlw by Molmil
Solution Structure of the Human Ubiquitin-conjugating Enzyme Variant Uev1a
Descriptor: Ubiquitin-conjugating enzyme E2 variant 1
Authors:Hau, D.D, Lewis, M.J, Saltibus, L.F, Pastushok, L, Xiao, W, Spyracopoulos, L.
Deposit date:2006-07-10
Release date:2006-09-05
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structure and interactions of the ubiquitin-conjugating enzyme variant human uev1a: implications for enzymatic synthesis of polyubiquitin chains(,).
Biochemistry, 45, 2006
6LK0
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BU of 6lk0 by Molmil
Crystal structure of human wild type TRIP13
Descriptor: Pachytene checkpoint protein 2 homolog
Authors:Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J.
Deposit date:2019-12-17
Release date:2020-01-22
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
6K98
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BU of 6k98 by Molmil
Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family
Descriptor: GH12 beta-1, 4-endoglucanase
Authors:Hong, Y, Tao, T, Pengjun, S, Jiaming, C, Xiaoyu, W, Chen, H, yingguo, B, Bin, Y.
Deposit date:2019-06-14
Release date:2020-06-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.032 Å)
Cite:Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family
To Be Published
6K9D
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BU of 6k9d by Molmil
glycoside hydrolase family 12 (GH12) englucanase
Descriptor: GH12 beta-1, 4-endoglucanase
Authors:Hong, Y, Tao, T, Pengjun, S, Jiaming, C, Xiaoyu, W, Chen, H, Yingguo, B, Bin, Y.
Deposit date:2019-06-14
Release date:2020-06-17
Method:X-RAY DIFFRACTION (1.505 Å)
Cite:Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family
To Be Published
6WCZ
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BU of 6wcz by Molmil
CryoEM structure of full-length ZIKV NS5-hSTAT2 complex
Descriptor: Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION
Authors:Boxiao, W, Stephanie, T, Kang, Z, Maria, T.S, Jian, F, Jiuwei, L, Linfeng, G, Wendan, R, Yanxiang, C, Ethan, C.V, HeaJin, H, Matthew, J.E, Sean, E.O, Adolfo, G.S, Hong, Z, Rong, H, Jikui, S.
Deposit date:2020-03-31
Release date:2020-07-08
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis for STAT2 suppression by flavivirus NS5.
Nat.Struct.Mol.Biol., 27, 2020
7XF3
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BU of 7xf3 by Molmil
The structure of HLA-B*1501/BM58-66AF9
Descriptor: 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen
Authors:Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L.
Deposit date:2022-03-31
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape.
J Immunol., 210, 2023
4NRG
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BU of 4nrg by Molmil
Crystal Structure of a human Mms2/Ubc13 D118G mutant
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2013-11-26
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
8E90
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BU of 8e90 by Molmil
Inhibition of Human Menin by SNDX-5613
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, ...
Authors:McKeever, B.M, KULKARNI, S, McGeehan, G.M.
Deposit date:2022-08-26
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:MEN1 mutations mediate clinical resistance to menin inhibition.
Nature, 615, 2023
6AEJ
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BU of 6aej by Molmil
Crystal structure of human FTO in complex with small-molecule inhibitors
Descriptor: (E)-3-[3-nitro-4,5-bis(oxidanyl)phenyl]-2-(1,3-oxazinan-3-ylcarbonyl)prop-2-enenitrile, Alpha-ketoglutarate-dependent dioxygenase FTO,Alpha-ketoglutarate-dependent dioxygenase FTO, ZINC ION
Authors:Wang, Y, Cao, R, Peng, S, Zhang, W, Huang, N.
Deposit date:2018-08-05
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1.
Sci Transl Med, 11, 2019
6AK4
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BU of 6ak4 by Molmil
Crystal structure of human FTO in complex with small-molecule inhibitors
Descriptor: (~{E})-2-cyano-~{N},~{N}-diethyl-3-[3-nitro-4,5-bis(oxidanyl)phenyl]prop-2-enamide, Alpha-ketoglutarate-dependent dioxygenase FTO,Alpha-ketoglutarate-dependent dioxygenase FTO, ZINC ION
Authors:Wang, Y, Cao, R, Peng, S, Zhang, W, Huang, N.
Deposit date:2018-08-30
Release date:2019-07-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1.
Sci Transl Med, 11, 2019
8TWC
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BU of 8twc by Molmil
Acinetobacter phage AP205 T=3 VLP
Descriptor: Coat protein
Authors:Meng, R, Xing, Z, Zhang, J.
Deposit date:2023-08-20
Release date:2024-03-06
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024
8TVA
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BU of 8tva by Molmil
Outer Mat-T4P complex
Descriptor: Fimbrial protein, Maturation protein
Authors:Meng, R, Xing, Z, Thongchol, J, Zhang, J.
Deposit date:2023-08-17
Release date:2024-03-06
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (8.55 Å)
Cite:Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024
8TOC
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BU of 8toc by Molmil
Acinetobacter phage AP205
Descriptor: Coat protein, Maturation protein, RNA (4269-MER)
Authors:Meng, R, Xing, Z, Chang, J, Zhang, J.
Deposit date:2023-08-03
Release date:2024-03-06
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024
8TOB
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BU of 8tob by Molmil
Acinetobacter GP16 Type IV pilus
Descriptor: Fimbrial protein
Authors:Meng, R, Xing, Z, Zhang, J.
Deposit date:2023-08-03
Release date:2024-03-06
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024
8TV9
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BU of 8tv9 by Molmil
Inner Mat-T4P complex
Descriptor: Fimbrial protein, Maturation protein
Authors:Meng, R, Xing, Z, Thongchol, J, Zhang, J.
Deposit date:2023-08-17
Release date:2024-03-06
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (8.15 Å)
Cite:Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024
8TW2
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BU of 8tw2 by Molmil
Acinetobacter phage AP205 T=4 VLP
Descriptor: Coat protein
Authors:Meng, R, Xing, Z, Zhang, J.
Deposit date:2023-08-19
Release date:2024-03-06
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024

 

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