4MWY
| Shanghai N9-laninamivir | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ... | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | 登録日 | 2013-09-25 | 公開日 | 2013-11-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses Cell Res., 23, 2013
|
|
4NHG
| Crystal Structure of 2G12 IgG Dimer | 分子名称: | 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein | 著者 | Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J. | 登録日 | 2013-11-05 | 公開日 | 2014-02-26 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (8.001 Å) | 主引用文献 | Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. Cell Rep, 5, 2013
|
|
4NHH
| Structure of 2G12 IgG Dimer | 分子名称: | 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein | 著者 | Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J. | 登録日 | 2013-11-05 | 公開日 | 2014-02-26 | 実験手法 | X-RAY DIFFRACTION (6.5 Å) | 主引用文献 | Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. Cell Rep, 5, 2013
|
|
5Y10
| SFTSV Gn head domain | 分子名称: | Membrane glycoprotein polyprotein, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F. | 登録日 | 2017-07-19 | 公開日 | 2017-09-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5Y0Y
| RVFV GN-AU | 分子名称: | GOLD ION, NSmGnGc | 著者 | Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F. | 登録日 | 2017-07-19 | 公開日 | 2017-09-13 | 最終更新日 | 2017-09-20 | 実験手法 | X-RAY DIFFRACTION (3.398 Å) | 主引用文献 | Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5Y11
| SFTSV GN with neutralizing antibody MAb4-5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAb 4-5 heavy chain, MAb 4-5 light chain, ... | 著者 | Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F. | 登録日 | 2017-07-19 | 公開日 | 2017-09-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5Y0W
| The structure of RVFV Gn head domain | 分子名称: | NSmGnGc | 著者 | Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F. | 登録日 | 2017-07-19 | 公開日 | 2017-09-13 | 最終更新日 | 2017-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5V8W
| |
6LUP
| Crystal structure of shark MHC CLASS I for 2.3 angstrom | 分子名称: | Beta-2-microglobulin, MHC class I protein, PHE-ALA-ASN-PHE-PHE-ILE-ARG-GLY-LEU | 著者 | Wu, Y, Xia, C. | 登録日 | 2020-01-30 | 公開日 | 2021-04-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | The Structure of a Peptide-Loaded Shark MHC Class I Molecule Reveals Features of the Binding between beta 2 -Microglobulin and H Chain Conserved in Evolution. J Immunol., 2021
|
|
7V51
| BVMO_negative mutant D432V | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative flavin-binding monooxygenase | 著者 | Wu, Y, Yu, H.-L. | 登録日 | 2021-08-16 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Precise regulation of the substrate selectivity of Baeyer-Villiger monooxygenase to minimize overoxidation of prazole sulfoxides. CHINESE J CATAL, 51, 2023
|
|
7F0I
| phosphodiesterase-9A in complex with inhibitor 4b | 分子名称: | 1-cyclopentyl-6-[[(2R)-1-(6-fluoranyl-2-azaspiro[3.3]heptan-2-yl)-1-oxidanylidene-propan-2-yl]amino]-5H-pyrazolo[3,4-d]pyrimidin-4-one, Isoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | 著者 | Wu, Y, Huang, Y.Y, Luo, H.B. | 登録日 | 2021-06-04 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.70000887 Å) | 主引用文献 | Discovery of Potent Phosphodiesterase-9 Inhibitors for the Treatment of Hepatic Fibrosis J.Med.Chem., 64, 2021
|
|
7V4X
| |
7V50
| |
7VHR
| Apostichopus japonicus ferritin | 分子名称: | Ferritin, MAGNESIUM ION | 著者 | Wu, Y, Su, X.R, Ming, T.H. | 登録日 | 2021-09-22 | 公開日 | 2022-03-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.756 Å) | 主引用文献 | Crystallographic characterization of a marine invertebrate ferritin from the sea cucumber Apostichopus japonicus. Febs Open Bio, 12, 2022
|
|
7Y74
| |
8UPS
| Structure of SARS-Cov2 3CLPro in complex with Compound 5 | 分子名称: | (1R,2S,5S)-N-{(2S,3R)-4-amino-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}-3-[N-(tert-butylcarbamoyl)-3-methyl-L-valyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5, PHOSPHATE ION | 著者 | Wu, Y, Qiang, D, Zhuang, N, Krishnamurthy, H, Klein, D.J. | 登録日 | 2023-10-23 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. J.Med.Chem., 67, 2024
|
|
8BOB
| |
5JQ9
| Yersinia pestis DHPS with pterine-sulfa conjugate Compound 16 | 分子名称: | 1,2-ETHANEDIOL, 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide, Dihydropteroate synthase | 著者 | Wu, Y, White, S.W. | 登録日 | 2016-05-04 | 公開日 | 2016-08-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. Bioorg.Med.Chem.Lett., 26, 2016
|
|
2FPL
| RadA recombinase in complex with AMP-PNP and low concentration of K+ | 分子名称: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Wu, Y, Qian, X, He, Y, Moya, I.A, Luo, Y. | 登録日 | 2006-01-16 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of Methanococcus Voltae Rada in Complex with Adp: hydrolysis-induced conformational change Biochemistry, 44, 2005
|
|
2FPK
| RadA recombinase in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA repair and recombination protein radA, MAGNESIUM ION, ... | 著者 | Wu, Y, Qian, X, He, Y, Moya, I.A, Luo, Y. | 登録日 | 2006-01-16 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Methanococcus Voltae Rada in Complex with Adp: hydrolysis-induced conformational change Biochemistry, 44, 2005
|
|
2FPM
| RadA recombinase in complex with AMP-PNP and high concentration of K+ | 分子名称: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Wu, Y, Qian, X, He, Y, Moya, I.A, Luo, Y. | 登録日 | 2006-01-16 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Methanoccocus Voltae Rada in Complex with Adp: hydrolysis-induced conformational change Biochemistry, 44, 2005
|
|
2GDJ
| Delta-62 RADA recombinase in complex with AMP-PNP and magnesium | 分子名称: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Wu, Y, Qian, X, He, Y, Luo, Y. | 登録日 | 2006-03-16 | 公開日 | 2006-05-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Rad51/RadA N-Terminal Domain Activates Nucleoprotein Filament ATPase Activity. Structure, 14, 2006
|
|
5LE2
| Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_15_D12_15_D12 | 分子名称: | ACETATE ION, DDD_D12_15_D12_15_D12, THIOCYANATE ION | 著者 | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | 登録日 | 2016-06-29 | 公開日 | 2017-08-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Rigidly connected multispecific artificial binders with adjustable geometries. Sci Rep, 7, 2017
|
|
5LEC
| Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_12_D12_12_D12 | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DDD_D12_12_D12_12_D12 | 著者 | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | 登録日 | 2016-06-29 | 公開日 | 2017-08-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | 主引用文献 | Rigidly connected multispecific artificial binders with adjustable geometries. Sci Rep, 7, 2017
|
|
5LEL
| Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_10_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein | 分子名称: | DD_Off7_10_3G124, Green fluorescent protein, Maltose-binding periplasmic protein | 著者 | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | 登録日 | 2016-06-30 | 公開日 | 2017-11-15 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Rigidly connected multispecific artificial binders with adjustable geometries. Sci Rep, 7, 2017
|
|