5LE8
 
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_15_D12 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DD_D12_15_D12, GLYCEROL, ... | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-29 | | Release date: | 2017-08-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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5LE7
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_13_D12 | | Descriptor: | DD_D12_13_D12, SULFATE ION | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-29 | | Release date: | 2017-08-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.104 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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5LW2
 | | Crystal structure of DARPin 5m3_D12 | | Descriptor: | ACETATE ION, DARPin_5m3_D12 | | Authors: | Batyuk, A, Wu, Y, Plueckthun, A. | | Deposit date: | 2016-09-15 | | Release date: | 2017-09-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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5LE3
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_09_D12 | | Descriptor: | DD_D12_09_D12 | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-29 | | Release date: | 2017-08-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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5LEB
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_06_D12_06_D12 | | Descriptor: | DDD_D12_06_D12_06_D12 | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-29 | | Release date: | 2017-08-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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5LE4
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_11_D12 | | Descriptor: | DD_D12_11_D12 | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-29 | | Release date: | 2017-08-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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5LEA
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_12_3G124 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DD_Off7_12_3G124 | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-29 | | Release date: | 2017-08-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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5LED
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_12_D12_12_D12 | | Descriptor: | DDD_D12_12_D12_12_D12 | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-29 | | Release date: | 2017-08-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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5LEM
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_11_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein | | Descriptor: | DD_Off7_11_3G124, Green fluorescent protein, Maltose-binding periplasmic protein | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-30 | | Release date: | 2017-08-02 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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5LE6
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_09_D12 | | Descriptor: | DD_D12_09_D12, GLYCEROL, SULFATE ION | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-29 | | Release date: | 2017-08-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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2FPL
 | | RadA recombinase in complex with AMP-PNP and low concentration of K+ | | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Wu, Y, Qian, X, He, Y, Moya, I.A, Luo, Y. | | Deposit date: | 2006-01-16 | | Release date: | 2006-01-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Methanococcus Voltae Rada in Complex with Adp: hydrolysis-induced conformational change
Biochemistry, 44, 2005
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2FPK
 | | RadA recombinase in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA repair and recombination protein radA, MAGNESIUM ION, ... | | Authors: | Wu, Y, Qian, X, He, Y, Moya, I.A, Luo, Y. | | Deposit date: | 2006-01-16 | | Release date: | 2006-01-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of Methanococcus Voltae Rada in Complex with Adp: hydrolysis-induced conformational change
Biochemistry, 44, 2005
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2FPM
 | | RadA recombinase in complex with AMP-PNP and high concentration of K+ | | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Wu, Y, Qian, X, He, Y, Moya, I.A, Luo, Y. | | Deposit date: | 2006-01-16 | | Release date: | 2006-01-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Methanoccocus Voltae Rada in Complex with Adp: hydrolysis-induced conformational change
Biochemistry, 44, 2005
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2GDJ
 | | Delta-62 RADA recombinase in complex with AMP-PNP and magnesium | | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Wu, Y, Qian, X, He, Y, Luo, Y. | | Deposit date: | 2006-03-16 | | Release date: | 2006-05-16 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Rad51/RadA N-Terminal Domain Activates Nucleoprotein Filament ATPase Activity.
Structure, 14, 2006
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5ITA
 | | Crystal Structure of BRAF Kinase Domain Bound to AZ-VEM | | Descriptor: | N-{2-cyano-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide, Serine/threonine-protein kinase B-raf | | Authors: | Wu, Y, Gavathiotis, E. | | Deposit date: | 2016-03-16 | | Release date: | 2016-08-10 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | An integrated model of RAF inhibitor action predicts inhibitor activity against oncogenic BRAF signaling
Cancer Cell, 30, 2016
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5JQ9
 | | Yersinia pestis DHPS with pterine-sulfa conjugate Compound 16 | | Descriptor: | 1,2-ETHANEDIOL, 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide, Dihydropteroate synthase | | Authors: | Wu, Y, White, S.W. | | Deposit date: | 2016-05-04 | | Release date: | 2016-08-10 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.101 Å) | | Cite: | Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents.
Bioorg.Med.Chem.Lett., 26, 2016
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2MRI
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2MR3
 | | A subunit of 26S proteasome lid complex | | Descriptor: | 26S proteasome regulatory subunit RPN9 | | Authors: | Wu, Y, Hu, Y, Jin, C. | | Deposit date: | 2014-06-30 | | Release date: | 2015-02-04 | | Last modified: | 2017-04-12 | | Method: | SOLUTION NMR | | Cite: | Solution structure of yeast Rpn9: insights into proteasome lid assembly.
J. Biol. Chem., 290, 2015
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2MQW
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4Z8L
 | | Crystal structure of DCAF1/SIV-MND VPX/MND SAMHD1 NTD ternary complex | | Descriptor: | Protein VPRBP, SAM domain and HD domain-containing protein, Vpx protein, ... | | Authors: | Koharudin, L.M, Wu, Y, Calero, G, Ahn, J, Gronenborn, A.M. | | Deposit date: | 2015-04-09 | | Release date: | 2015-06-17 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile alpha Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
J.Biol.Chem., 290, 2015
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3TZF
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3TYZ
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3TZN
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3QZ7
 | | T-3 ternary complex of Dpo4 | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*GP*GP*G)-3', 5'-D(*TP*TP*AP*CP*GP*CP*CP*TP*CP*GP*AP*TP*CP*AP*GP*TP*GP*CP*C)-3', ... | | Authors: | Pata, J.D, Wu, Y, Wilson, R.C. | | Deposit date: | 2011-03-04 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.998 Å) | | Cite: | The y-family DNA polymerase dpo4 uses a template slippage mechanism to create single-base deletions.
J.Bacteriol., 193, 2011
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3QZ8
 | | TT-4 ternary complex of Dpo4 | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*AP*GP*G)-3', 5'-D(*TP*TP*AP*CP*GP*CP*CP*TP*TP*GP*AP*TP*CP*AP*GP*TP*GP*CP*C)-3', ... | | Authors: | Pata, J.D, Wu, Y, Wilson, R.C. | | Deposit date: | 2011-03-04 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.999 Å) | | Cite: | The y-family DNA polymerase dpo4 uses a template slippage mechanism to create single-base deletions.
J.Bacteriol., 193, 2011
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