3OW3
 
 | | Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors | | 分子名称: | (2R)-3-(1H-indol-3-yl)-1-{4-[(5S)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}-1-oxopropan-2-amine, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | | 著者 | Dizon, F, Wu, W, Vigers, G.P.A, Brandhuber, B.J. | | 登録日 | 2010-09-17 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
|
|
3OW4
 | | Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors | | 分子名称: | (2R)-3-(1H-indol-3-yl)-1-{4-[(5S)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}-1-oxopropan-2-amine, GSK 3 beta peptide, RAC-alpha serine/threonine-protein kinase | | 著者 | Dizon, F, Wu, W, Vigers, G.P.A, Brandhuber, B.J. | | 登録日 | 2010-09-17 | | 公開日 | 2010-11-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
|
|
1N2D
 | | Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin | | 分子名称: | IQ2 AND IQ3 MOTIFS FROM MYO2P, A CLASS V MYOSIN, Myosin Light Chain | | 著者 | Terrak, M, Wu, G, Stafford, W.F, Lu, R.C, Dominguez, R. | | 登録日 | 2002-10-22 | | 公開日 | 2003-11-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the light chain-binding domain of myosin V.
Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
3LD1
 | | Crystal Structure of IBV Nsp2a | | 分子名称: | Replicase polyprotein 1a | | 著者 | Xu, Y, Cong, L, Wei, L, Fu, J, Chen, C, Yang, A, Tang, H, Bartlam, M, Rao, Z. | | 登録日 | 2010-01-12 | | 公開日 | 2011-05-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | | 主引用文献 | IBV nsp2 is an endosome-associated protein and viral pathogenicity factor
To be Published
|
|
7V97
 | | Arsenic-bound p53 DNA-binding domain mutant V272M | | 分子名称: | ARSENIC, Cellular tumor antigen p53, ZINC ION | | 著者 | Lu, M, Xing, Y.F, Wang, Z.Y, Ni, Y, Song, H.X. | | 登録日 | 2021-08-24 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties.
Sci Transl Med, 15, 2023
|
|
3OQU
 | | Crystal structure of native abscisic acid receptor PYL9 with ABA | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL9 | | 著者 | Zhang, X, Zhang, Q, Chen, Z. | | 登録日 | 2010-09-04 | | 公開日 | 2011-09-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural Insights into the Abscisic Acid Stereospecificity by the ABA Receptors PYR/PYL/RCAR
Plos One, 8, 2013
|
|
5WRV
 | | Complex structure of human SRP72/SRP68 | | 分子名称: | ACETATE ION, GLYCEROL, SODIUM ION, ... | | 著者 | Gao, Y, Chen, Z. | | 登録日 | 2016-12-04 | | 公開日 | 2017-06-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation
J Mol Cell Biol, 9, 2017
|
|
6IN8
 | | Crystal structure of MucB | | 分子名称: | Sigma factor AlgU regulatory protein MucB | | 著者 | Li, S, Zhang, Q, Bartlam, M. | | 登録日 | 2018-10-24 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa.
Febs J., 286, 2019
|
|
6IN9
 | |
6IN7
 | |
6JDS
 | |
6JDU
 | | Crystal structure of PRRSV nsp10 (helicase) | | 分子名称: | CALCIUM ION, PP1b, ZINC ION | | 著者 | Tang, C, Chen, Z. | | 登録日 | 2019-02-02 | | 公開日 | 2020-02-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Helicase of Type 2 Porcine Reproductive and Respiratory Syndrome Virus Strain HV Reveals a Unique Structure.
Viruses, 12, 2020
|
|
6JDR
 | |
5WRW
 | | Structure of human apo-SRP72 | | 分子名称: | SULFATE ION, Signal recognition particle subunit SRP72 | | 著者 | Gao, Y, Chen, Z. | | 登録日 | 2016-12-04 | | 公開日 | 2017-06-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation
J Mol Cell Biol, 9, 2017
|
|
2N8A
 | | 1H, 13C and 15N chemical shift assignments and solution structure for PARP-1 F1F2 domains in complex with a DNA single-strand break | | 分子名称: | DNA (45-MER), Poly [ADP-ribose] polymerase 1, ZINC ION | | 著者 | Neuhaus, D, Eustermann, S, Yang, J, Wu, W. | | 登録日 | 2015-10-08 | | 公開日 | 2015-12-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.
Mol.Cell, 60, 2015
|
|
4O7X
 | |
4PT1
 | |
4QKF
 | |
4QKB
 | | Crystal structure of seleno-methionine labelled human ALKBH7 in complex with alpha-ketoglutarate and Mn(II) | | 分子名称: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial, ... | | 著者 | Wang, G, He, Q, Chen, Z. | | 登録日 | 2014-06-05 | | 公開日 | 2014-08-20 | | 最終更新日 | 2015-10-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolism
J.Biol.Chem., 289, 2014
|
|
4QKD
 | |
4RAZ
 | |
4RAY
 | |
4RB3
 | |
4RB0
 | |
4RB2
 | |
