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4QKD

Crystal structure of human ALKBH7 in complex with alpha-ketoglutarate and Mn(II)

Summary for 4QKD
Entry DOI10.2210/pdb4qkd/pdb
Related4QKB 4QKF
DescriptorAlpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial, MANGANESE (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total)
Functional Keywordsalkbh7, dioxygenase, metal-binding, oxidoreductase, programmed necrosis, fat metabolism
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion matrix : Q9BT30
Total number of polymer chains3
Total formula weight68597.63
Authors
Wang, G.,Chen, Z. (deposition date: 2014-06-06, release date: 2014-08-20, Last modification date: 2023-12-06)
Primary citationWang, G.,He, Q.,Feng, C.,Liu, Y.,Deng, Z.,Qi, X.,Wu, W.,Mei, P.,Chen, Z.
The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolism
J.Biol.Chem., 289:27924-27936, 2014
Cited by
PubMed: 25122757
DOI: 10.1074/jbc.M114.590505
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.35 Å)
Structure validation

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