1Z0B
| Crystal Structure of A. fulgidus Lon proteolytic domain E506A mutant | Descriptor: | CALCIUM ION, Putative protease La homolog type | Authors: | Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A. | Deposit date: | 2005-03-01 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases J.Mol.Biol., 351, 2005
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5N0I
| Crystal structure of NDM-1 in complex with beta-mercaptoethanol - new refinement | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Raczynska, J.E, Shabalin, I.G, Jaskolski, M, Minor, W, Wlodawer, A, King, D.T, Strynadka, N.C.J. | Deposit date: | 2017-02-03 | Release date: | 2017-04-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | A close look onto structural models and primary ligands of metallo-beta-lactamases. Drug Resist. Updat., 40, 2018
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1FMU
| STRUCTURE OF NATIVE PROTEINASE A IN P3221 SPACE GROUP. | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, SACCHAROPEPSIN, ... | Authors: | Gustchina, A, Li, M, Phylip, L.H, Lees, W.E, Kay, J, Wlodawer, A. | Deposit date: | 2000-08-18 | Release date: | 2002-07-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An unusual orientation for Tyr75 in the active site of the aspartic proteinase from Saccharomyces cerevisiae. Biochem.Biophys.Res.Commun., 295, 2002
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3D9A
| High Resolution Crystal Structure Structure of HyHel10 Fab Complexed to Hen Egg Lysozyme | Descriptor: | Heavy Chain of HyHel10 Antibody Fragment (Fab), Light Chain of HyHel10 Antibody Fragment (Fab), Lysozyme C | Authors: | DeSantis, M.E, Li, M, Shanmuganathan, A, Acchione, M, Walter, R, Wlodawer, A, Smith-Gill, S. | Deposit date: | 2008-05-27 | Release date: | 2008-06-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies. Mol.Immunol., 47, 2009
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5O2E
| Crystal structure of NDM-1 in complex with hydrolyzed cefuroxime - new refinement | Descriptor: | (2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Metallo-beta-lactamase type 2, SULFATE ION, ... | Authors: | Raczynska, J.E, Shabalin, I.G, Jaskolski, M, Minor, W, Wlodawer, A. | Deposit date: | 2017-05-20 | Release date: | 2018-12-26 | Last modified: | 2023-02-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | A close look onto structural models and primary ligands of metallo-beta-lactamases. Drug Resist. Updat., 40, 2018
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5O9J
| Crystal structure of transcription factor IIB Mja mini-intein | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AMMONIUM ION, ... | Authors: | Mikula, K.M, Iwai, H, Zhou, D, Wlodawer, A. | Deposit date: | 2017-06-19 | Release date: | 2017-11-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the Persistence of Homing Endonucleases in Transcription Factor IIB Inteins. J. Mol. Biol., 429, 2017
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5O9I
| Crystal structure of transcription factor IIB Mvu mini-intein | Descriptor: | Transcription initiation factor IIB,Transcription initiation factor IIB | Authors: | Mikula, K.M, Iwai, H, Li, M, Wlodawer, A. | Deposit date: | 2017-06-19 | Release date: | 2017-11-01 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for the Persistence of Homing Endonucleases in Transcription Factor IIB Inteins. J. Mol. Biol., 429, 2017
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1KP5
| Cyclic Green Fluorescent Protein | Descriptor: | Green Fluorescent Protein, SULFATE ION | Authors: | Hofmann, A, Iwai, H, Plueckthun, A, Wlodawer, A. | Deposit date: | 2001-12-28 | Release date: | 2002-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of cyclized green fluorescent protein. Acta Crystallogr.,Sect.D, 58, 2002
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5O2F
| Crystal structure of NDM-1 in complex with hydrolyzed ampicillin - new refinement | Descriptor: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Raczynska, J.E, Shabalin, I.G, Jaskolski, M, Minor, W, Wlodawer, A. | Deposit date: | 2017-05-20 | Release date: | 2018-12-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | A close look onto structural models and primary ligands of metallo-beta-lactamases. Drug Resist. Updat., 40, 2018
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3FNU
| Crystal structure of KNI-10006 bound histo-aspartic protease (HAP) from Plasmodium falciparum | Descriptor: | (4R)-3-[(2S,3S)-3-{[(2,6-dimethylphenoxy)acetyl]amino}-2-hydroxy-4-phenylbutanoyl]-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, HAP protein | Authors: | Bhaumik, P, Gustchina, A, Wlodawer, A. | Deposit date: | 2008-12-26 | Release date: | 2009-05-12 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of the histo-aspartic protease (HAP) from Plasmodium falciparum. J.Mol.Biol., 388, 2009
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3FNS
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3LIZ
| crystal structure of bla g 2 complexed with Fab 4C3 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C3 monoclonal antibody Heavy Chain, ... | Authors: | Li, M, Gustchina, A, Glesner, J, Wunschmann, S, Pomes, A, Wlodawer, A. | Deposit date: | 2010-01-25 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding. Plos One, 6, 2011
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3FNT
| Crystal structure of pepstatin A bound histo-aspartic protease (HAP) from Plasmodium falciparum | Descriptor: | 1,2-ETHANEDIOL, HAP protein, Inhibitor, ... | Authors: | Bhaumik, P, Gustchina, A, Wlodawer, A. | Deposit date: | 2008-12-26 | Release date: | 2009-05-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structures of the histo-aspartic protease (HAP) from plasmodium falciparum. J.Mol.Biol., 388, 2009
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1Z0V
| Crystal Structure of A. fulgidus Lon proteolytic domain | Descriptor: | Putative protease La homolog type | Authors: | Dauter, Z, Botos, I, LaRonde-LeBlanc, N, Wlodawer, A. | Deposit date: | 2005-03-02 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Pathological crystallography: case studies of several unusual macromolecular crystals. Acta Crystallogr.,Sect.D, 61, 2005
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1Z0T
| Crystal Structure of A. fulgidus Lon proteolytic domain | Descriptor: | Putative protease La homolog type | Authors: | Dauter, Z, Botos, I, LaRonde-LeBlanc, N, Wlodawer, A. | Deposit date: | 2005-03-02 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Pathological crystallography: case studies of several unusual macromolecular crystals. Acta Crystallogr.,Sect.D, 61, 2005
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3GEF
| Crystal structure of the R482W mutant of lamin A/C | Descriptor: | Lamin-A/C | Authors: | Magracheva, E, Kozlov, S, Stuart, C, Wlodawer, A, Zdanov, A. | Deposit date: | 2009-02-25 | Release date: | 2009-08-04 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the lamin A/C R482W mutant responsible for dominant familial partial lipodystrophy (FPLD). Acta Crystallogr.,Sect.F, 65, 2009
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3OG4
| The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P21212 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 28 receptor, alpha (Interferon, ... | Authors: | Miknis, Z.J, Magracheva, E, Lei, W, Zdanov, A, Kotenko, S.V, Wlodawer, A. | Deposit date: | 2010-08-16 | Release date: | 2010-10-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1. J.Mol.Biol., 404, 2010
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3OG6
| The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P212121 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Interleukin 28 receptor, ... | Authors: | Miknis, Z.J, Magracheva, E, Lei, W, Zdanov, A, Kotenko, S.V, Wlodawer, A. | Deposit date: | 2010-08-16 | Release date: | 2010-10-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1. J.Mol.Biol., 404, 2010
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1HG1
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3QS1
| Crystal structure of KNI-10006 complex of Plasmepsin I (PMI) from Plasmodium falciparum | Descriptor: | (4R)-3-[(2S,3S)-3-{[(2,6-dimethylphenoxy)acetyl]amino}-2-hydroxy-4-phenylbutanoyl]-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, GLYCEROL, Plasmepsin-1 | Authors: | Bhaumik, P, Gustchina, A, Wlodawer, A. | Deposit date: | 2011-02-19 | Release date: | 2011-05-11 | Last modified: | 2012-12-12 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum. J.Struct.Biol., 175, 2011
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3QRV
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3QVC
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1HFW
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1HG0
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3QVI
| Crystal structure of KNI-10395 bound histo-aspartic protease (HAP) from Plasmodium falciparum | Descriptor: | (4R)-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-3-[(2S,3S)-2-hydroxy-3-{[S-methyl-N-(phenylacetyl)-L-cysteinyl]amino}-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ... | Authors: | Bhaumik, P, Gustchina, A, Wlodawer, A. | Deposit date: | 2011-02-25 | Release date: | 2011-10-12 | Last modified: | 2013-09-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into the activation and inhibition of histo-aspartic protease from Plasmodium falciparum. Biochemistry, 50, 2011
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