3QVC

Crystal structure of histo-aspartic protease (HAP) zymogen from Plasmodium falciparum

Summary for 3QVC

Entry DOI	10.2210/pdb3qvc/pdb
Related	3QVI
Descriptor	Histo-aspartic protease, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	histo-aspartic protease, hap, plasmepsin, aspartic protease, malaria, zymogen, hydrolase
Biological source	Plasmodium falciparum
Total number of polymer chains	1
Total formula weight	52065.31
Authors	Bhaumik, P.,Gustchina, A.,Wlodawer, A. (deposition date: 2011-02-25, release date: 2011-10-12, Last modification date: 2011-11-30)
Primary citation	Bhaumik, P.,Xiao, H.,Hidaka, K.,Gustchina, A.,Kiso, Y.,Yada, R.Y.,Wlodawer, A. Structural insights into the activation and inhibition of histo-aspartic protease from Plasmodium falciparum. Biochemistry, 50:8862-8879, 2011 Cited by PubMed: 21928835 DOI: 10.1021/bi201118z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation