Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8SP1
DownloadVisualize
BU of 8sp1 by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGIAAGTGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2023-05-01
Release date:2023-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8SMJ
DownloadVisualize
BU of 8smj by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAATGGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2023-04-26
Release date:2023-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8SMH
DownloadVisualize
BU of 8smh by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAAGTGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2023-04-26
Release date:2023-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8T9U
DownloadVisualize
BU of 8t9u by Molmil
Human PU.1 ETS-domain (165-270) in complex with d(AATAAGCGIAAGTGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2023-06-26
Release date:2023-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
2LWG
DownloadVisualize
BU of 2lwg by Molmil
NMR Structure of the Self-Complementary 10 mer DNA Oligonucleotide 5'-GGATATATCC-3'.
Descriptor: DNA (5'-D(*GP*GP*AP*TP*AP*TP*AP*TP*CP*C)-3')
Authors:Rettig, M, Germann, M.W, Wilson, W, Wang, S.
Deposit date:2012-07-31
Release date:2013-01-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Molecular basis for sequence-dependent induced DNA bending.
Chembiochem, 14, 2013
2LWH
DownloadVisualize
BU of 2lwh by Molmil
NMR Structure of the Self-Complementary 10 mer DNA Duplex 5'-GGATATATCC-3' in Complex with Netropsin
Descriptor: DNA (5'-D(*GP*GP*AP*TP*AP*TP*AP*TP*CP*C)-3'), NETROPSIN
Authors:Rettig, M, Germann, M.W, Wilson, W, Wang, S.
Deposit date:2012-07-31
Release date:2013-01-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Molecular basis for sequence-dependent induced DNA bending.
Chembiochem, 14, 2013
7KWK
DownloadVisualize
BU of 7kwk by Molmil
DNA-DB1879 complex: The DNA sequence 5'-CGCGAATTCGCG-3' presents a binding site for the heterocyclic small molecule (DB1879).
Descriptor: 2-[5-(4-carbamimidoylphenyl)thiophen-2-yl]-1H-indole-6-carboximidamide, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Ogbonna, E, Fang, Z, Wilson, D.W.
Deposit date:2020-12-01
Release date:2021-12-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines.
Bioorg.Med.Chem., 68, 2022
2FJV
DownloadVisualize
BU of 2fjv by Molmil
RT29 Bound to D(CTTAATTCGAATTAAG) in complex with MMLV RT Catalytic Fragment
Descriptor: 2-(4-(4-CARBAMIMIDOYLPHENOXY)PHENYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXIMIDAMIDE, 5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', ...
Authors:Goodwin, K.D, Georgiadis, M.M.
Deposit date:2006-01-03
Release date:2006-06-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128, 2006
2FJX
DownloadVisualize
BU of 2fjx by Molmil
RT29 bound to D(CTTGAATGCATTCAAG) in complex with MMLV RT catalytic fragment
Descriptor: 2-(4-(4-CARBAMIMIDOYLPHENOXY)PHENYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXIMIDAMIDE, 5'-D(*CP*TP*TP*GP*AP*AP*TP*G)-3', 5'-D(P*CP*AP*TP*TP*CP*AP*AP*G)-3', ...
Authors:Goodwin, K.D, Georgiadis, M.M.
Deposit date:2006-01-03
Release date:2006-06-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128, 2006
2FJW
DownloadVisualize
BU of 2fjw by Molmil
d(CTTGAATGCATTCAAG) in complex with MMLV RT catalytic fragment
Descriptor: 5'-D(*CP*TP*TP*GP*AP*AP*TP*G)-3', 5'-D(P*CP*AP*TP*TP*CP*AP*AP*G)-3', Reverse transcriptase
Authors:Goodwin, K.D, Georgiadis, M.M.
Deposit date:2006-01-03
Release date:2006-06-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128, 2006
2GYX
DownloadVisualize
BU of 2gyx by Molmil
Crystal structure of DB884- D(CGCGAATTCGCG)2 complex at 1.86 A resolution.
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, N,N'-(1H-PYRROLE-2,5-DIYLDI-4,1-PHENYLENE)DIBENZENECARBOXIMIDAMIDE
Authors:Lee, M.P.H, Neidle, S.
Deposit date:2006-05-10
Release date:2007-05-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Induced fit conformational changes of a "reversed amidine" heterocycle: optimized interactions in a DNA minor groove complex.
J.Am.Chem.Soc., 129, 2007
3U0U
DownloadVisualize
BU of 3u0u by Molmil
Crystal structure of the DB1883-D(CGCGAATTCGCG)2 complex at 1.24 A resolution
Descriptor: 2-(4'-carbamimidoylbiphenyl-4-yl)-1H-indole-6-carboximidamide, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION
Authors:Wei, D.G, Neidle, S.
Deposit date:2011-09-29
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3U2N
DownloadVisualize
BU of 3u2n by Molmil
Crystal structure of DNA(CGCGAATTCGCG)2 at 1.25 angstroms
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION
Authors:Wei, D.G, Neidle, S.
Deposit date:2011-10-04
Release date:2013-04-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3U08
DownloadVisualize
BU of 3u08 by Molmil
Crystal structure of DB1963-D(CGCGAATTCGCG)2 complex at 1.25 A resolution
Descriptor: 4'-(5-carbamimidoyl-1H-benzimidazol-2-yl)biphenyl-4-carboxamide, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION
Authors:Wei, D.G, Neidle, S.
Deposit date:2011-09-28
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3U05
DownloadVisualize
BU of 3u05 by Molmil
Crystal structure of DB1804-D(CGCGAATTCGCG)2 complex
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 6-(1,4,5,6-tetrahydropyrimidin-2-yl)-2-[4'-(1,4,5,6-tetrahydropyrimidin-2-yl)biphenyl-4-yl]-1H-indole, MAGNESIUM ION
Authors:Wei, D.G, Neidle, S.
Deposit date:2011-09-28
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3FSI
DownloadVisualize
BU of 3fsi by Molmil
Crystal structure of a trypanocidal 4,4'-Bis(imidazolinylamino)diphenylamine bound to DNA
Descriptor: 5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', ACETATE ION, ...
Authors:Glass, L.S, Georgiadis, M.M, Goodwin, K.D.
Deposit date:2009-01-09
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA.
Biochemistry, 48, 2009
6ASF
DownloadVisualize
BU of 6asf by Molmil
NMR and Restrained Molecular Dynamics Determination of the Structure of an Aza-Benzimidazole Derivative Complex with the DNA Minor Groove of an -AAGATA- Sequence
Descriptor: DNA (5'-D(*CP*CP*AP*AP*GP*AP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*TP*CP*TP*TP*GP*G)-3')
Authors:Harika, N.K, Germann, M.W, Boykin, D.W.
Deposit date:2017-08-24
Release date:2018-01-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:First Structure of a Designed Minor Groove Binding Heterocyclic Cation that Specifically Recognizes Mixed DNA Base Pair Sequences.
Chemistry, 23, 2017
8E5Y
DownloadVisualize
BU of 8e5y by Molmil
Human PU.1 ETS-Domain Bound to d(AATAAGCGGAAGTGGG) Acetate Free at pH 5.4
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2022-08-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8E3K
DownloadVisualize
BU of 8e3k by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2022-08-17
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8E3R
DownloadVisualize
BU of 8e3r by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2022-08-17
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EBH
DownloadVisualize
BU of 8ebh by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAATGGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2022-08-31
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EKJ
DownloadVisualize
BU of 8ekj by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAATGGAAGTGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*TP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2022-09-21
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EE9
DownloadVisualize
BU of 8ee9 by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAATGGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2022-09-06
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EJ6
DownloadVisualize
BU of 8ej6 by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAATGGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2022-09-16
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EK3
DownloadVisualize
BU of 8ek3 by Molmil
Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAATGGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2022-09-19
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023

219869

數據於2024-05-15公開中

PDB statisticsPDBj update infoContact PDBjnumon