5U68
 
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8GYD
 | | Structure of Schistosoma japonicum Glutathione S-transferase bound with the ligand complex of 16 | | 分子名称: | (2R)-2-[[2-(5-chloranylthiophen-2-yl)-4-oxidanylidene-6-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]quinazolin-3-yl]methyl]-3-(4-chlorophenyl)propanoic acid, ETHANOL, Glutathione S-transferase class-mu 26 kDa isozyme | | 著者 | Wen, X, Jin, R, Hu, H, Zhu, J, Song, W, Lu, X. | | 登録日 | 2022-09-22 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1 H )-one Focused DNA-Encoded Library.
J.Med.Chem., 66, 2023
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8EAY
 | | HMPV F complex with 4I3 Fab | | 分子名称: | 4I3 heavy chain protein, 4I3 light chain protein, Fusion glycoprotein F0 | | 著者 | Wen, X, Jardetzky, T.S. | | 登録日 | 2022-08-30 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
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8E2U
 | | HMPV F monomer bound to RSV-199 Fab | | 分子名称: | Fusion glycoprotein F0, RSV-199 heavy chain, RSV-199 light chain | | 著者 | Wen, X, Jardetzky, T.S. | | 登録日 | 2022-08-16 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
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8DZW
 | | RSV F trimer bound to RSV-199 Fab | | 分子名称: | RSV fusion protein, RSV-199 Heavy chain protein, RSV-199 Light chain protein | | 著者 | Wen, X, Jardetzky, T.S. | | 登録日 | 2022-08-08 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | | 主引用文献 | Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
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8EBP
 | | HMPV F dimer bound to RSV-199 Fab | | 分子名称: | Fusion glycoprotein F0, RSV-199 heavy chain protein, RSV-199 light chain protein | | 著者 | Wen, X, Jardetzky, T.S. | | 登録日 | 2022-08-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
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4DAG
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8JLZ
 | | ST1936-5HT6R complex | | 分子名称: | 2-(5-chloranyl-2-methyl-1~{H}-indol-3-yl)-N,N-dimethyl-ethanamine, 5-hydroxytryptamine receptor 6, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Wen, X, Sun, J. | | 登録日 | 2023-06-04 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structural insight into the selective agonist ST1936 binding of serotonin receptor 5-HT6.
Biochem.Biophys.Res.Commun., 671, 2023
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1L0L
 | | structure of bovine mitochondrial cytochrome bc1 complex with a bound fungicide famoxadone | | 分子名称: | Cytochrome B, Cytochrome c1, heme protein, ... | | 著者 | Gao, X, Wen, X, Yu, C.A, Esser, L, Tsao, S, Quinn, B, Zhang, L, Yu, L, Xia, D. | | 登録日 | 2002-02-11 | | 公開日 | 2003-04-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Famoxadone: The Role of Aromatic-Aromatic Interaction in Inhibition
Biochemistry, 41, 2003
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1L0N
 | | native structure of bovine mitochondrial cytochrome bc1 complex | | 分子名称: | Cytochrome B, Cytochrome c1, heme protein, ... | | 著者 | Gao, X, Wen, X, Yu, C.A, Esser, L, Tsao, S, Quinn, B, Zhang, L, Yu, L, Xia, D. | | 登録日 | 2002-02-11 | | 公開日 | 2003-04-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Famoxadone: The Role of Aromatic-Aromatic Interaction in Inhibition
Biochemistry, 41, 2003
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4ZDS
 | | Crystal Structure of core DNA binding domain of Arabidopsis Thaliana Transcription Factor Ethylene-Insensitive 3 | | 分子名称: | Protein ETHYLENE INSENSITIVE 3 | | 著者 | Song, J, Zhu, C, Zhang, X, Wen, X, Liu, L, Peng, J, Guo, H, Yi, C. | | 登録日 | 2015-04-18 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Biochemical and Structural Insights into the Mechanism of DNA Recognition by Arabidopsis ETHYLENE INSENSITIVE3.
Plos One, 10, 2015
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1ZTM
 | | Structure of the Uncleaved Paramyxovirus (hPIV3) Fusion Protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein | | 著者 | Yin, H.S, Paterson, R.G, Wen, X, Lamb, R.A, Jardetzky, T.S. | | 登録日 | 2005-05-27 | | 公開日 | 2005-07-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein
Proc.Natl.Acad.Sci.USA, 102, 2005
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2B9B
 | | Structure of the Parainfluenza Virus 5 F Protein in its Metastable, Pre-fusion Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 | | 著者 | Yin, H.-S, Wen, X, Paterson, R.G, Lamb, R.A, Jardetzky, T.S. | | 登録日 | 2005-10-11 | | 公開日 | 2006-01-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation
Nature, 439, 2006
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1NU1
 | | Crystal Structure of Mitochondrial Cytochrome bc1 Complexed with 2-nonyl-4-hydroxyquinoline N-oxide (NQNO) | | 分子名称: | 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE, Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D. | | 登録日 | 2003-01-30 | | 公開日 | 2003-10-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site
Biochemistry, 42, 2003
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1NTZ
 | | Crystal Structure of Mitochondrial Cytochrome bc1 Complex Bound with Ubiquinone | | 分子名称: | Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D. | | 登録日 | 2003-01-30 | | 公開日 | 2003-10-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site
Biochemistry, 42, 2003
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1NTK
 | | Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1 | | 分子名称: | Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D. | | 登録日 | 2003-01-30 | | 公開日 | 2003-10-07 | | 最終更新日 | 2016-03-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site
Biochemistry, 42, 2003
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1NTM
 | | Crystal Structure of Mitochondrial Cytochrome bc1 Complex at 2.4 Angstrom | | 分子名称: | Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C, Xia, D. | | 登録日 | 2003-01-30 | | 公開日 | 2003-10-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site
Biochemistry, 42, 2003
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3MAW
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7D77
 | | Cryo-EM structure of the cortisol-bound adhesion receptor GPR97-Go complex | | 分子名称: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Adhesion G protein-coupled receptor G3; GPR97, CHOLESTEROL, ... | | 著者 | Ping, Y, Mao, C, Xiao, P, Zhao, R, Jiang, Y, Yang, Z, An, W, Shen, D, Yang, F, Zhang, H, Qu, C, Shen, Q, Tian, C, Li, Z, Li, S, Wang, G, Tao, X, Wen, X, Zhong, Y, Yang, J, Yi, F, Yu, X, Xu, E, Zhang, Y, Sun, J. | | 登録日 | 2020-10-03 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structures of the glucocorticoid-bound adhesion receptor GPR97-G o complex.
Nature, 589, 2021
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7D76
 | | Cryo-EM structure of the beclomethasone-bound adhesion receptor GPR97-Go complex | | 分子名称: | (8~{S},9~{R},10~{S},11~{S},13~{S},14~{S},16~{S},17~{R})-9-chloranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-17-(2-oxidanylethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, Adhesion G protein-coupled receptor G3; GPR97, CHOLESTEROL, ... | | 著者 | Ping, Y, Mao, C, Xiao, P, Zhao, R, Jiang, Y, Yang, Z, An, W, Shen, D, Yang, F, Zhang, H, Qu, C, Shen, Q, Tian, C, Li, Z, Li, S, Wang, G, Tao, X, Wen, X, Zhong, Y, Yang, J, Yi, F, Yu, X, Xu, E, Zhang, Y, Sun, J. | | 登録日 | 2020-10-03 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structures of the glucocorticoid-bound adhesion receptor GPR97-G o complex.
Nature, 589, 2021
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2QN1
 | | Glycogen Phosphorylase b in complex with asiatic acid | | 分子名称: | Glycogen phosphorylase, muscle form, asiatic acid | | 著者 | Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G. | | 登録日 | 2007-07-17 | | 公開日 | 2008-06-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies
J.Med.Chem., 51, 2008
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2QN2
 | | Glycogen Phosphorylase b in complex with Maslinic Acid | | 分子名称: | Glycogen phosphorylase, muscle form, maslinic acid | | 著者 | Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G. | | 登録日 | 2007-07-17 | | 公開日 | 2008-06-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | | 主引用文献 | Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies
J.Med.Chem., 51, 2008
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8AJP
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6S3D
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4X8S
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