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6XFI
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BU of 6xfi by Molmil
Crystal Structures of beta-1,4-N-Acetylglucosaminyltransferase 2 (POMGNT2): Structural Basis for Inherited Muscular Dystrophies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, ...
Authors:Halmo, S.M, Yeh, J, Wells, L, Moremen, K.W, Lanzilotta, W.N.
Deposit date:2020-06-15
Release date:2021-04-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of beta-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies.
Acta Crystallogr D Struct Biol, 77, 2021
6XI2
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BU of 6xi2 by Molmil
Apo form of POMGNT2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-GLY-ALA-GLY-ALA-ALA-ALA-ALA-ALA-ALA, ...
Authors:Halmo, S.M, Yeh, J, Wells, L, Moremen, K.W, Lanzilotta, W.N.
Deposit date:2020-06-19
Release date:2021-04-21
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Crystal structures of beta-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies.
Acta Crystallogr D Struct Biol, 77, 2021
5V7J
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BU of 5v7j by Molmil
Crystal Structure at 3.7 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer with Four Glycans (N197, N276, N362, and N462) removed in Complex with Neutralizing Antibodies 3H+109L and 35O22.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 35O22 Fab heavy chain, ...
Authors:Stewart-Jones, G.B.E, Zhou, T, Kwong, P.D.
Deposit date:2017-03-20
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.907 Å)
Cite:Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.
Cell Rep, 19, 2017
3D34
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BU of 3d34 by Molmil
Structure of the F-spondin domain of mindin
Descriptor: CALCIUM ION, NICKEL (II) ION, Spondin-2
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2008-05-09
Release date:2009-02-17
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule.
Embo J., 28, 2009
6ORN
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BU of 6orn by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074
Descriptor: 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
Deposit date:2019-04-30
Release date:2019-06-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6ORO
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BU of 6oro by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ...
Authors:Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
Deposit date:2019-04-30
Release date:2019-06-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6ORQ
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BU of 6orq by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ...
Authors:Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
Deposit date:2019-04-30
Release date:2019-06-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6ORP
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BU of 6orp by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ...
Authors:Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
Deposit date:2019-04-30
Release date:2019-06-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
8FR7
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BU of 8fr7 by Molmil
A hinge glycan regulates spike bending and impacts coronavirus infectivity
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Pintilie, G, Wilson, E, Chmielewski, D, Schmid, M.F, Jin, J, Chen, M, Singharoy, A, Chiu, W.
Deposit date:2023-01-06
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:A hinge glycan regulates spike bending and impacts coronavirus infectivity
To Be Published
4MPS
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BU of 4mps by Molmil
Crystal structure of rat Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1), Northeast Structural Genomics Consortium Target RnR367A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactoside alpha-2,6-sialyltransferase 1
Authors:Forouhar, F, Meng, L, Milaninia, S, Seetharaman, J, Su, M, Kornhaber, G, Montelione, G.T, Hunt, J.F, Moremen, K.W, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-09-13
Release date:2013-09-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Enzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT alpha 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION.
J.Biol.Chem., 288, 2013
7SBI
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BU of 7sbi by Molmil
Tandem diubiquitin-like domain from chicken 2'-5'-oligoadenylate synthetase-like protein
Descriptor: 2'-5' oligoadenylate synthase
Authors:Freitas, B.T, Pegan, S.D.
Deposit date:2021-09-24
Release date:2022-01-12
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The Structure and Immune Regulatory Implications of the Ubiquitin-Like Tandem Domain Within an Avian 2'-5' Oligoadenylate Synthetase-Like Protein
Front Immunol, 12, 2022
6MW5
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BU of 6mw5 by Molmil
UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Platinum
Descriptor: 1,2-ETHANEDIOL, PLATINUM (II) ION, UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase, ...
Authors:Kim, H.W, Wood, Z.A, West, C.M.
Deposit date:2018-10-29
Release date:2019-10-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii .
J.Biol.Chem., 295, 2020
6MW8
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BU of 6mw8 by Molmil
UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Manganese
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ...
Authors:Kim, H.W, Wood, Z.A, West, C.M.
Deposit date:2018-10-29
Release date:2019-10-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.756 Å)
Cite:A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii .
J.Biol.Chem., 295, 2020
3UP1
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BU of 3up1 by Molmil
Crystal structure of the unliganded human interleukin-7 receptor extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:McElroy, C.A, Holland, P.J, Walsh, S.T.R.
Deposit date:2011-11-17
Release date:2012-02-08
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural reorganization of the interleukin-7 signaling complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GLL
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BU of 4gll by Molmil
Crystal structure of human UDP-xylose synthase.
Descriptor: GUANIDINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Wood, Z.A, Polizzi, S.J.
Deposit date:2012-08-14
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human UDP-alpha-d-xylose Synthase and Escherichia coli ArnA Conserve a Conformational Shunt That Controls Whether Xylose or 4-Keto-Xylose Is Produced.
Biochemistry, 51, 2012
5D8J
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BU of 5d8j by Molmil
Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes.
Descriptor: Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ...
Authors:Doyle, C, Birrane, G.
Deposit date:2015-08-17
Release date:2016-01-13
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
5C0N
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BU of 5c0n by Molmil
Development of a monoclonal antibody targeting secreted aP2 to treat diabetes and fatty liver disease
Descriptor: Fab CA33 Heavy chain, Fab CA33 light chain, Fatty acid-binding protein, ...
Authors:Doyle, C.
Deposit date:2015-06-12
Release date:2015-06-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015

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