4JHR
 
 | | An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs | | Descriptor: | G-protein-signaling modulator 2 | | Authors: | Pan, Z, Zhu, J, Shang, Y, Wei, Z, Jia, M, Xia, C, Wen, W, Wang, W, Zhang, M. | | Deposit date: | 2013-03-05 | | Release date: | 2013-06-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs
Structure, 21, 2013
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4U7U
 | | Crystal structure of RNA-guided immune Cascade complex from E.coli | | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | | Authors: | Zhao, H, Sheng, G, Wang, J, Wang, M, Bunkoczi, G, Gong, W, Wei, Z, Wang, Y. | | Deposit date: | 2014-07-31 | | Release date: | 2014-08-27 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.003 Å) | | Cite: | Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
Nature, 515, 2014
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6D26
 | | Crystal structure of the prostaglandin D2 receptor CRTH2 with fevipiprant | | Descriptor: | OLEIC ACID, Prostaglandin D2 receptor 2, Endolysin chimera, ... | | Authors: | Wang, L, Yao, D, Deepak, K, Liu, H, Gong, W, Fan, H, Wei, Z, Zhang, C. | | Deposit date: | 2018-04-13 | | Release date: | 2018-10-03 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.798 Å) | | Cite: | Structures of the Human PGD2Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition.
Mol. Cell, 72, 2018
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6D27
 | | Crystal structure of the prostaglandin D2 receptor CRTH2 with CAY10471 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, OLEIC ACID, ... | | Authors: | Wang, L, Yao, D, Deepak, K, Liu, H, Gong, W, Fan, H, Wei, Z, Zhang, C. | | Deposit date: | 2018-04-13 | | Release date: | 2018-10-03 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.738 Å) | | Cite: | Structures of the Human PGD2Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition.
Mol. Cell, 72, 2018
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6C1R
 | | Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist avacopan | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MALONATE ION, OLEIC ACID, ... | | Authors: | Liu, H, Wang, L, Wei, Z, Zhang, C. | | Deposit date: | 2018-01-05 | | Release date: | 2018-05-30 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
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6C1Q
 | | Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist NDT9513727 | | Descriptor: | 1-(1,3-benzodioxol-5-yl)-~{N}-(1,3-benzodioxol-5-ylmethyl)-~{N}-[(3-butyl-2,5-diphenyl-imidazol-4-yl)methyl]methanamine, PMX53, Soluble cytochrome b562, ... | | Authors: | Liu, H, Wang, L, Wei, Z, Zhang, C. | | Deposit date: | 2018-01-05 | | Release date: | 2018-05-30 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
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3TFM
 | | Myosin X PH1N-PH2-PH1C tandem | | Descriptor: | Myosin X, PHOSPHATE ION | | Authors: | Yu, J, Lu, Q, Yan, J, Wei, Z, Zhang, M. | | Deposit date: | 2011-08-16 | | Release date: | 2011-12-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor
MOLECULAR BIOLOGY OF THE CELL, 22, 2011
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3G5B
 | | The structure of UNC5b cytoplasmic domain | | Descriptor: | Netrin receptor UNC5B, PHOSPHATE ION | | Authors: | Wang, R, Wei, Z, Zhang, M. | | Deposit date: | 2009-02-04 | | Release date: | 2009-04-07 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor
Mol.Cell, 33, 2009
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3H8D
 | | Crystal structure of Myosin VI in complex with Dab2 peptide | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, Disabled homolog 2, ... | | Authors: | Yu, C, Feng, W, Wei, Z, Zhang, M. | | Deposit date: | 2009-04-29 | | Release date: | 2009-09-29 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Myosin VI undergoes cargo-mediated dimerization
Cell(Cambridge,Mass.), 138, 2009
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2IS9
 | | Structure of yeast DCN-1 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Defective in cullin neddylation protein 1, ... | | Authors: | Yang, X, Zhou, J, Sun, L, Wei, Z, Gao, J, Gong, W, Xu, R.M, Rao, Z, Liu, Y. | | Deposit date: | 2006-10-16 | | Release date: | 2007-06-26 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural basis for the function of DCN-1 in protein Neddylation.
J.Biol.Chem., 282, 2007
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2QT5
 | | Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide | | Descriptor: | (ASN)(ASN)(LEU)(GLN)(ASP)(GLY)(THR)(GLU)(VAL), 1,2-ETHANEDIOL, ACETIC ACID, ... | | Authors: | Long, J, Wei, Z, Feng, W, Zhao, Y, Zhang, M. | | Deposit date: | 2007-08-01 | | Release date: | 2008-06-03 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1.
J.Mol.Biol., 375, 2008
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2RIV
 | | Crystal structure of the reactive loop cleaved human Thyroxine Binding Globulin | | Descriptor: | GLYCEROL, SULFATE ION, Thyroxine-binding globulin | | Authors: | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | | Deposit date: | 2007-10-12 | | Release date: | 2008-10-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
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2RIW
 | | The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin | | Authors: | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | | Deposit date: | 2007-10-12 | | Release date: | 2008-10-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
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2VDY
 | | Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol | | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | | Authors: | Zhou, A, Wei, Z, Read, R.J. | | Deposit date: | 2007-10-13 | | Release date: | 2008-05-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.
J.Mol.Biol., 380, 2008
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2VDX
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2WY1
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2WXW
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2WXX
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2WY0
 | | Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122 | | Descriptor: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | | Authors: | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | | Deposit date: | 2009-11-11 | | Release date: | 2010-10-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
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2WXZ
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3RO3
 | | crystal structure of LGN/mInscuteable complex | | Descriptor: | CHLORIDE ION, ETHANOL, G-protein-signaling modulator 2, ... | | Authors: | Zhu, J, Wen, W, Shang, Y, Wei, Z, Pan, Z, Wang, W, Zhang, M. | | Deposit date: | 2011-04-25 | | Release date: | 2012-03-07 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
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3RO2
 | | Structures of the LGN/NuMA complex | | Descriptor: | G-protein-signaling modulator 2, GLYCEROL, peptide of Nuclear mitotic apparatus protein 1 | | Authors: | Shang, Y, Wei, Z. | | Deposit date: | 2011-04-25 | | Release date: | 2012-03-07 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
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3CF4
 | | Structure of the CODH component of the M. barkeri ACDS complex | | Descriptor: | ACETIC ACID, Acetyl-CoA decarboxylase/synthase alpha subunit, Acetyl-CoA decarboxylase/synthase epsilon subunit, ... | | Authors: | Gong, W, Hao, B, Wei, Z, Ferguson Jr, D.J, Tallant, T, Krzycki, J.A, Chan, M.K. | | Deposit date: | 2008-03-01 | | Release date: | 2008-07-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the alpha2 epsilon2 Ni-dependent CO dehydrogenase component of the Methanosarcina barkeri acetyl-CoA decarboxylase/synthase complex
Proc.Natl.Acad.Sci.USA, 105, 2008
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2I6K
 | | Crystal structure of human type I IPP isomerase complexed with a substrate analog | | Descriptor: | ACETIC ACID, AMINOETHANOLPYROPHOSPHATE, Isopentenyl-diphosphate delta-isomerase 1, ... | | Authors: | Zhang, C, Wei, Z, Gong, W. | | Deposit date: | 2006-08-29 | | Release date: | 2007-06-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of human IPP isomerase: new insights into the catalytic mechanism
J.Mol.Biol., 366, 2007
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2FQD
 | | Crystal Structures of E. coli Laccase CueO under different copper binding situations | | Descriptor: | Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ... | | Authors: | Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W. | | Deposit date: | 2006-01-18 | | Release date: | 2007-01-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of E. coli laccase CueO at different copper concentrations.
Biochem.Biophys.Res.Commun., 354, 2007
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