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6L9O
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BU of 6l9o by Molmil
Crystal structure of FABP7 apo
Descriptor: Fatty acid-binding protein, brain
Authors:Wei, P.C, Yin, L.
Deposit date:2019-11-10
Release date:2020-11-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystal structure of FABP7 apo
To Be Published
5FM9
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BU of 5fm9 by Molmil
human Notch 1, EGF 4-7
Descriptor: CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
Authors:Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C.
Deposit date:2015-11-02
Release date:2016-04-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
5FMA
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BU of 5fma by Molmil
human Notch 1, EGF 4-7
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C.
Deposit date:2015-11-02
Release date:2016-04-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
6BCA
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BU of 6bca by Molmil
A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, A-kinase anchor protein 13, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
6BCB
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BU of 6bcb by Molmil
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
5Z9S
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BU of 5z9s by Molmil
Functional and Structural Characterization of a beta-Glucosidase Involved in Saponin Metabolism from Intestinal Bacteria
Descriptor: Glycosyl hydrolase family 3 protein, beta-D-glucopyranose
Authors:Yan, S, Wei, P.C, Li, J.R.
Deposit date:2018-02-05
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional and structural characterization of a beta-glucosidase involved in saponin metabolism from intestinal bacteria.
Biochem. Biophys. Res. Commun., 496, 2018
3KZ1
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BU of 3kz1 by Molmil
Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 11, ...
Authors:Chen, Z, Sternweis, P.C, Sprang, S.R.
Deposit date:2009-12-07
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
J.Biol.Chem., 285, 2010
1SHZ
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BU of 1shz by Molmil
Crystal Structure of the p115RhoGEF rgRGS Domain in A Complex with Galpha(13):Galpha(i1) Chimera
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine Nucleotide-Binding Protein Galpha(13):Galpha(i1) Chimera, MAGNESIUM ION, ...
Authors:Chen, Z, Singer, W.D, Sternweis, P.C, Sprang, S.R.
Deposit date:2004-02-26
Release date:2005-01-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.
Nat.Struct.Mol.Biol., 12, 2005
6BC0
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BU of 6bc0 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 28, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
6BC1
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BU of 6bc1 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated Rac1 Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
3ODX
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BU of 3odx by Molmil
Crystal Structure of an N-terminally Truncated Linker-DH/PH Domains of p115-RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-08-12
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODO
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BU of 3odo by Molmil
Crystal Structure of the DH/PH Domains of p115-RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODW
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BU of 3odw by Molmil
Crystal Structure of the Linker-DH/PH domains of p115-RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3P6A
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BU of 3p6a by Molmil
Crystal Structure of the DH/PH domains of p115-RhoGEF (R399E mutant)
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-10-11
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
5YLF
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BU of 5ylf by Molmil
MCR-1 complex with D-glucose
Descriptor: Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION, beta-D-glucopyranose
Authors:Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L.
Deposit date:2017-10-17
Release date:2017-11-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5XS3
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BU of 5xs3 by Molmil
Crystal structure of HLA Class I antigen
Descriptor: Heavy Chain, Light Chain, P
Authors:Wei, P.C, Yang, Y, Liu, Z.X, Luo, Z.Q, Tu, W.Y, Han, J.Y, Deng, Y.H, Yin, L.
Deposit date:2017-06-12
Release date:2017-09-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Characterization of Autoantigen Presentation by HLA-C*06:02 in Psoriasis
J. Invest. Dermatol., 137, 2017
5YLC
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BU of 5ylc by Molmil
Crystal Structure of MCR-1 Catalytic Domain
Descriptor: Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
Authors:Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L.
Deposit date:2017-10-17
Release date:2017-11-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5YLE
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BU of 5yle by Molmil
MCR-1 complex with ethanolamine (ETA)
Descriptor: ETHANOLAMINE, Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
Authors:Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L.
Deposit date:2017-10-17
Release date:2017-11-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
8IVL
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BU of 8ivl by Molmil
FABP7 complexed with Cholesterol
Descriptor: CHOLESTEROL, Fatty acid-binding protein, brain
Authors:Wei, P.C, Zhao, K, Yin, L.
Deposit date:2023-03-28
Release date:2024-02-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
J.Cell Biol., 223, 2024
8IVF
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BU of 8ivf by Molmil
FABP7 complexed with 25-HC
Descriptor: 25-HYDROXYCHOLESTEROL, Fatty acid-binding protein, brain
Authors:Wei, P.C, Zhao, K, Yin, L.
Deposit date:2023-03-27
Release date:2024-02-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
J.Cell Biol., 223, 2024
6L9K
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BU of 6l9k by Molmil
H2-Ld a1a2 complexed with A5 peptide
Descriptor: H2-Ld a1a2, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE
Authors:Wei, P.C, Yin, L.
Deposit date:2019-11-10
Release date:2020-11-18
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
6L9N
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BU of 6l9n by Molmil
H2-Ld complexed with A5 peptide
Descriptor: MHC, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE, b2m
Authors:Wei, P.C, Yin, L.
Deposit date:2019-11-10
Release date:2020-11-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
6L9L
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BU of 6l9l by Molmil
1D4 TCR recognition of H2-Ld a1a2 A5 Peptide Complexes
Descriptor: H2-Ld a1a2, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE, T Cell Receptor
Authors:Wei, P.C, Yin, L.
Deposit date:2019-11-10
Release date:2020-11-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
6L9M
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BU of 6l9m by Molmil
H2-Ld complexed with AH1 peptide
Descriptor: H2-Ld, SER-PRO-SER-TYR-VAL-TYR-HIS-GLN-PHE, b2m
Authors:Wei, P.C, Yin, L.
Deposit date:2019-11-10
Release date:2020-11-18
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
8U77
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BU of 8u77 by Molmil
Crystal structure of Taf14 in complex with Yng1
Descriptor: Protein YNG1, Transcription initiation factor TFIID subunit 14
Authors:Nguyen, M.C, Wei, P.C, Zhang, G.Y, Kutateladze, T.G.
Deposit date:2023-09-14
Release date:2024-08-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Molecular insight into interactions between the Taf14, Yng1 and Sas3 subunits of the NuA3 complex.
Nat Commun, 15, 2024

 

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