2P6V
 
 | | Structure of TAFH domain of the human TAF4 subunit of TFIID | | Descriptor: | SULFATE ION, Transcription initiation factor TFIID subunit 4 | | Authors: | Wang, X, Truckses, D.M, Takada, S, Matsumura, T, Tanese, N, Jacobson, R.H. | | Deposit date: | 2007-03-19 | | Release date: | 2007-05-15 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conserved region I of human coactivator TAF4 binds to a short hydrophobic motif present in transcriptional regulators.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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5DQR
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3VBR
 | | Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (room temperature) | | Descriptor: | Genome Polyprotein, capsid protein VP0, capsid protein VP1, ... | | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | Deposit date: | 2012-01-02 | | Release date: | 2012-02-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
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3VBF
 | | Crystal structure of formaldehyde treated human Enterovirus 71 (space group I23) | | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Genome Polyprotein, ... | | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | Deposit date: | 2012-01-02 | | Release date: | 2012-02-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
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3VBO
 | | Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (cryo at 100K) | | Descriptor: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | Deposit date: | 2012-01-02 | | Release date: | 2012-02-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
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5K0K
 | | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2434 | | Descriptor: | 15-{4-[(4-methylpiperazin-1-yl)methyl]phenyl}-4,5,6,7,9,10,11,12-octahydro-2,16-(azenometheno)pyrrolo[2,1-d][1,3,5,9]te traazacyclotetradecin-8(3H)-one, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Wang, X, Liu, J, Zhang, W, Stashko, M.A, Nichols, J, DeRyckere, D, Miley, M.J, Norris-Drouin, J, Chen, Z, Machius, M, Wood, E, Graham, D.K, Earp, H.S, Graham, K, Kireev, D, Frye, S.V. | | Deposit date: | 2016-05-17 | | Release date: | 2017-01-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.545 Å) | | Cite: | Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors.
ACS Med Chem Lett, 7, 2016
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6X12
 | | Inward-facing Apo-open state of the glutamate transporter homologue GltPh | | Descriptor: | Glutamate transporter homologue GltPh, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | Authors: | Wang, X, Boudker, O. | | Deposit date: | 2020-05-18 | | Release date: | 2020-11-18 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters.
Elife, 9, 2020
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3NFC
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1G2E
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1AQL
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1FXL
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1AKN
 | | STRUCTURE OF BILE-SALT ACTIVATED LIPASE | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BILE-SALT ACTIVATED LIPASE | | Authors: | Wang, X, Zhang, X. | | Deposit date: | 1997-05-23 | | Release date: | 1998-05-27 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of bovine bile salt activated lipase: insights into the bile salt activation mechanism.
Structure, 5, 1997
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3TKQ
 | | Crystal structure of full-length human peroxiredoxin 4 with mixed conformation | | Descriptor: | Peroxiredoxin-4 | | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | | Deposit date: | 2011-08-28 | | Release date: | 2011-10-05 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
Biochem.J., 2011
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3TKP
 | | Crystal structure of full-length human peroxiredoxin 4 in the reduced form | | Descriptor: | Peroxiredoxin-4 | | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | | Deposit date: | 2011-08-28 | | Release date: | 2011-10-05 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
Biochem.J., 2011
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3TKR
 | | Crystal structure of full-length human peroxiredoxin 4 with T118E mutation | | Descriptor: | Peroxiredoxin-4 | | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | | Deposit date: | 2011-08-28 | | Release date: | 2011-10-05 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
Biochem.J., 2011
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1DDJ
 | | CRYSTAL STRUCTURE OF HUMAN PLASMINOGEN CATALYTIC DOMAIN | | Descriptor: | PLASMINOGEN | | Authors: | Wang, X, Terzyan, S, Tang, J, Loy, J, Lin, X, Zhang, X. | | Deposit date: | 1999-11-10 | | Release date: | 2000-02-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Human plasminogen catalytic domain undergoes an unusual conformational change upon activation.
J.Mol.Biol., 295, 2000
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3TKS
 | | Crystal structure of full-length human peroxiredoxin 4 in three different redox states | | Descriptor: | PEROXIDE ION, Peroxiredoxin-4 | | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | | Deposit date: | 2011-08-28 | | Release date: | 2011-10-05 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
Biochem.J., 2011
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8YM2
 | | Crystal structure of AIDA-1 PTB domain in complex with SynGAP NPxF motif | | Descriptor: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B, Ras/Rap GTPase-activating protein SynGAP | | Authors: | Wang, X, Wang, Y, Cai, Q, Zhang, M. | | Deposit date: | 2024-03-08 | | Release date: | 2024-05-29 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.
J.Mol.Biol., 436, 2024
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7P3O
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7P3M
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7P3P
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1M8W
 | | CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-19 RNA | | Descriptor: | 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*GP*UP*CP*CP*AP*G)-3', 5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', ... | | Authors: | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | | Deposit date: | 2002-07-26 | | Release date: | 2002-09-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN
CELL(CAMBRIDGE,MASS.), 110, 2002
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3VBS
 | | Crystal structure of human Enterovirus 71 | | Descriptor: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | Deposit date: | 2012-01-02 | | Release date: | 2012-02-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
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3VBH
 | | Crystal structure of formaldehyde treated human enterovirus 71 (space group R32) | | Descriptor: | CHLORIDE ION, Genome Polyprotein, capsid protein VP1, ... | | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | Deposit date: | 2012-01-02 | | Release date: | 2012-02-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
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3VBU
 | | Crystal structure of empty human Enterovirus 71 particle | | Descriptor: | Genome Polyprotein, capsid protein VP0, capsid protein VP1, ... | | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | Deposit date: | 2012-01-02 | | Release date: | 2012-02-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
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