4RB0
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4RB2
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2XKB
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2XKA
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5GV2
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5ISY
| Crystal structure of Nudix family protein with NAD | Descriptor: | NADH pyrophosphatase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | Authors: | Zhang, D, Guan, Z, Zou, T, Yin, P. | Deposit date: | 2016-03-15 | Release date: | 2016-09-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.354 Å) | Cite: | Structural basis of prokaryotic NAD-RNA decapping by NudC Cell Res., 26, 2016
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3S5L
| Crystal structure of CD4 mutant bound to HLA-DR1 | Descriptor: | GLYCEROL, HA peptide, HLA class II histocompatibility antigen DR beta chain, ... | Authors: | Li, Y. | Deposit date: | 2011-05-23 | Release date: | 2011-09-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA, 108, 2011
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3S4S
| Crystal structure of CD4 mutant bound to HLA-DR1 | Descriptor: | GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | Li, Y. | Deposit date: | 2011-05-20 | Release date: | 2011-09-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA, 108, 2011
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5JRH
| Crystal structure of Salmonella enterica acetyl-CoA synthetase (Acs) in complex with cAMP and Coenzyme A | Descriptor: | (R,R)-2,3-BUTANEDIOL, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Acetyl-coenzyme A synthetase, ... | Authors: | Shen, L, Zhang, Y. | Deposit date: | 2016-05-06 | Release date: | 2016-12-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.644 Å) | Cite: | Cyclic AMP Inhibits the Activity and Promotes the Acetylation of Acetyl-CoA Synthetase through Competitive Binding to the ATP/AMP Pocket. J. Biol. Chem., 292, 2017
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2GIZ
| Structural and functional analysis of Natrin, a member of crisp-3 family blocks a variety of ion channels | Descriptor: | Natrin-1 | Authors: | Jiang, T, Wang, F, Li, H, Yin, C, Zhou, Y, Shu, Y, Qi, Z, Lin, Z. | Deposit date: | 2006-03-30 | Release date: | 2006-11-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural and functional analysis of natrin, a venom protein that targets various ion channels Biochem.Biophys.Res.Commun., 351, 2006
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2EAX
| Crystal structure of human PGRP-IBETAC in complex with glycosamyl muramyl pentapeptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-methyl 2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-beta-D-glucopyranoside, GLYCOSAMYL MURAMYL PENTAPEPTIDE, Peptidoglycan recognition protein-I-beta | Authors: | Cho, S. | Deposit date: | 2007-02-03 | Release date: | 2007-10-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins Proc.Natl.Acad.Sci.Usa, 104, 2007
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2EAV
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7YHK
| Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5 | Descriptor: | 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zheng, Q, Li, S, Li, T, Xue, W, Sun, H. | Deposit date: | 2022-07-13 | Release date: | 2022-08-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
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5IWW
| Crystal structure of RNA editing factor of designer PLS-type PPR/9R protein in complex with MORF9/RIP9 | Descriptor: | Multiple organellar RNA editing factor 9, chloroplastic, PLS9-PPR | Authors: | Yan, J, Zhang, Q, Guan, Z, Zou, T, Yin, P. | Deposit date: | 2016-03-23 | Release date: | 2017-03-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing Nat Plants, 3, 2017
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5IZW
| Crystal structure of RNA editing specific factor of designer PLS-type PPR-9R protein | Descriptor: | PLS9-PPR | Authors: | Yan, J, Zhang, Q, Guan, Z, Zou, T, Yin, P. | Deposit date: | 2016-03-26 | Release date: | 2017-03-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.738 Å) | Cite: | MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing Nat Plants, 3, 2017
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8H0Z
| Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-122 Conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | Authors: | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | Deposit date: | 2022-09-30 | Release date: | 2022-11-09 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023
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3R21
| Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (Part I) | Descriptor: | MAGNESIUM ION, N-(2-aminoethyl)-N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide, Serine/threonine-protein kinase 6 | Authors: | Zhang, L, Fan, J, Chong, J.-H, Cesena, A, Tam, B, Gilson, C, Boykin, C, Wang, D, Marcotte, D, Le Brazidec, J.-Y, Aivazian, D, Piao, J, Lundgren, K, Hong, K, Vu, K, Nguyen, K. | Deposit date: | 2011-03-11 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I). Bioorg.Med.Chem.Lett., 21, 2011
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4QR5
| Brd4 Bromodomain 1 complex with its novel inhibitors | Descriptor: | Bromodomain-containing protein 4, N-[3-(cyclopentylsulfamoyl)-5-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)phenyl]cyclopropanecarboxamide | Authors: | Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. | Deposit date: | 2014-06-30 | Release date: | 2015-07-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization J.Med.Chem., 58, 2015
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4QR3
| Brd4 Bromodomain 1 complex with its novel inhibitors | Descriptor: | Bromodomain-containing protein 4, N-cyclopentyl-3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzenesulfonamide | Authors: | Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. | Deposit date: | 2014-06-30 | Release date: | 2015-07-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.374 Å) | Cite: | Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization J.Med.Chem., 58, 2015
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4QR4
| Brd4 Bromodomain 1 complex with its novel inhibitors | Descriptor: | 2-chloro-N-cyclopentyl-5-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzenesulfonamide, Bromodomain-containing protein 4 | Authors: | Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. | Deposit date: | 2014-06-30 | Release date: | 2015-07-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization J.Med.Chem., 58, 2015
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3R22
| Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (Part I) | Descriptor: | N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide, Serine/threonine-protein kinase 6 | Authors: | Zhang, L, Fan, J, Chong, J.-H, Cesana, A, Tam, B, Gilson, C, Boykin, C, Wang, D, Marcotte, D, Le Brazidec, J.-Y, Aivazian, D, Piao, J, Lundgren, K, Hong, K, Vu, K, Nguyen, K. | Deposit date: | 2011-03-11 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I). Bioorg.Med.Chem.Lett., 21, 2011
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8JD9
| Cyro-EM structure of the Na+/H+ antipoter SOS1 from Arabidopsis thaliana,class1 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Sodium/hydrogen exchanger 7 | Authors: | Yang, G.H, Zhang, Y.M, Zhou, J.Q, Jia, Y.T, Xu, X, Fu, P, Wu, H.Y. | Deposit date: | 2023-05-13 | Release date: | 2023-11-08 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Structural basis for the activity regulation of Salt Overly Sensitive 1 in Arabidopsis salt tolerance. Nat.Plants, 9, 2023
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8JDA
| Cyro-EM structure of the Na+/H+ antipoter SOS1 from Arabidopsis thaliana,class2 | Descriptor: | Sodium/hydrogen exchanger 7 | Authors: | Yang, G.H, Zhang, Y.M, Zhou, J.Q, Jia, Y.T, Xu, X, Fu, P, Wu, H.Y. | Deposit date: | 2023-05-13 | Release date: | 2023-11-08 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Structural basis for the activity regulation of Salt Overly Sensitive 1 in Arabidopsis salt tolerance. Nat.Plants, 9, 2023
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6A50
| structure of benzoylformate decarboxylases in complex with cofactor TPP | Descriptor: | MAGNESIUM ION, THIAMINE DIPHOSPHATE, benzoylformate decarboxylases | Authors: | Guo, Y, Wang, S, Nie, Y, Li, S. | Deposit date: | 2018-06-21 | Release date: | 2019-02-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Synthetic Pathway for Acetyl-Coenzyme A Biosynthesis Nat Commun, 2019
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7QUO
| FimH lectin domain in complex with oligomannose-6 | Descriptor: | FimH, NICKEL (II) ION, SULFATE ION, ... | Authors: | Bouckaert, J, Bourenkov, G.P. | Deposit date: | 2022-01-18 | Release date: | 2023-02-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors J.Biol.Chem., 299, 2023
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