5JRH
Crystal structure of Salmonella enterica acetyl-CoA synthetase (Acs) in complex with cAMP and Coenzyme A
Summary for 5JRH
Entry DOI | 10.2210/pdb5jrh/pdb |
Descriptor | Acetyl-coenzyme A synthetase, COENZYME A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... (6 entities in total) |
Functional Keywords | acetyl-coenzyme a synthetase, camp, amp-forming, acetyl-coenzyme a, ligase |
Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
Total number of polymer chains | 2 |
Total formula weight | 149217.87 |
Authors | |
Primary citation | Han, X.,Shen, L.,Wang, Q.,Cen, X.,Wang, J.,Wu, M.,Li, P.,Zhao, W.,Zhang, Y.,Zhao, G. Cyclic AMP Inhibits the Activity and Promotes the Acetylation of Acetyl-CoA Synthetase through Competitive Binding to the ATP/AMP Pocket. J. Biol. Chem., 292:1374-1384, 2017 Cited by PubMed: 27974467DOI: 10.1074/jbc.M116.753640 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.644 Å) |
Structure validation
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