7M8J
 
 | | SARS-CoV-2 S-NTD + Fab CM25 | | Descriptor: | CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1 | | Authors: | Johnson, N.V, Mclellan, J.S. | | Deposit date: | 2021-03-29 | | Release date: | 2021-05-19 | | Last modified: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
Science, 372, 2021
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8FOW
 | | Ternary complex of CDK2 with small molecule ligands TW8672 and Dinaciclib | | Descriptor: | 1,2-ETHANEDIOL, 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-nitrobenzoic acid, 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium, ... | | Authors: | Schonbrunn, E, Sun, L. | | Deposit date: | 2023-01-03 | | Release date: | 2023-05-31 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.
Nat Commun, 14, 2023
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8FP5
 | | CDK2 liganded with ATP and Mg2+ | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cyclin-dependent kinase 2, ... | | Authors: | Schonbrunn, E, Sun, L. | | Deposit date: | 2023-01-04 | | Release date: | 2023-05-31 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.
Nat Commun, 14, 2023
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8FP0
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8H4I
 | | DHA-bound FFAR4 in complex with Gs | | Descriptor: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | He, Y, Yin, H. | | Deposit date: | 2022-10-10 | | Release date: | 2023-06-21 | | Last modified: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity.
Cell Res., 33, 2023
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8H4L
 | | DHA-bound FFAR4 in complex with Gq | | Descriptor: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | He, Y, Yin, H. | | Deposit date: | 2022-10-10 | | Release date: | 2023-06-21 | | Last modified: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity.
Cell Res., 33, 2023
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8H4K
 | | GW9508-bound FFAR4 in complex with Gq | | Descriptor: | 3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | He, Y, Yin, H. | | Deposit date: | 2022-10-10 | | Release date: | 2023-06-21 | | Last modified: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity.
Cell Res., 33, 2023
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6CGI
 | | Structure of Salmonella Effector SseK3 | | Descriptor: | Type III secretion system effector protein, URIDINE-5'-DIPHOSPHATE | | Authors: | Chung, I.Y.W, Cygler, M. | | Deposit date: | 2018-02-20 | | Release date: | 2018-02-28 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways.
Mol.Cell Proteomics, 18, 2019
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7ENO
 | | Mutant strain M3 of foot-and-mouth disease virus type O | | Descriptor: | VP1 of O type FMDV capsid, VP2 of O type FMDV capsid, VP3 of O type FMDV capsid, ... | | Authors: | Dong, H, Lu, Y. | | Deposit date: | 2021-04-18 | | Release date: | 2021-06-02 | | Last modified: | 2022-01-26 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity.
J.Virol., 95, 2021
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7ENP
 | | wild type of O type Foot-and-mouth disease virus | | Descriptor: | VP1 of O type FMDV capsid protein, VP2 of O type FMDV capsid protein, VP3 of O type FMDV capsid protein, ... | | Authors: | Dong, H, Lu, Y. | | Deposit date: | 2021-04-18 | | Release date: | 2021-06-02 | | Last modified: | 2022-01-26 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity.
J.Virol., 95, 2021
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8IFO
 | | Crystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter | | Descriptor: | DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3'), Estrogen-related receptor gamma, ... | | Authors: | Xu, T, Zhen, X, Liu, J. | | Deposit date: | 2023-02-19 | | Release date: | 2023-03-29 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | ERR gamma-DBD undergoes dimerization and conformational rearrangement upon binding to the downstream site of the DR1 element.
Biochem.Biophys.Res.Commun., 656, 2023
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8IYS
 | | TUG891-bound FFAR4 in complex with Gq | | Descriptor: | 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | He, Y, Yin, H. | | Deposit date: | 2023-04-06 | | Release date: | 2023-06-21 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity.
Cell Res., 33, 2023
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8KAE
 | | 16d-bound human SPNS2 | | Descriptor: | 3-[3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine, NbFab chain L, NbFab-H chain, ... | | Authors: | He, Y, Duan, Y. | | Deposit date: | 2023-08-03 | | Release date: | 2024-01-03 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Structural basis of Sphingosine-1-phosphate transport via human SPNS2.
Cell Res., 34, 2024
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7Y78
 | | Crystal structure of Cry78Aa | | Descriptor: | 1,2-ETHANEDIOL, AMMONIUM ION, Toxin | | Authors: | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | | Deposit date: | 2022-06-21 | | Release date: | 2022-08-31 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity.
Commun Biol, 5, 2022
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7Y79
 | | Crystal structure of Cry78Aa | | Descriptor: | Toxin | | Authors: | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | | Deposit date: | 2022-06-21 | | Release date: | 2022-08-31 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity.
Commun Biol, 5, 2022
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7XZ9
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7XZD
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7XZF
 | | Wild type of the N-terminal domain of fucoidan lyase FdlA | | Descriptor: | Fucoidan lyase, GLYCEROL, IMIDAZOLE, ... | | Authors: | Wang, J, Li, M, Pan, X. | | Deposit date: | 2022-06-02 | | Release date: | 2022-09-28 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
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7XZ8
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7XZB
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7XZA
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7XZE
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7XZ7
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7XZC
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7YBL
 | | SARS-CoV-2 B.1.620 variant spike (close state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, X, Fu, W. | | Deposit date: | 2022-06-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants.
Virol Sin, 37, 2022
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